Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Technology Trends and Patenting Prospects of Medicinal Plants in Korea

한국 약용작물의 기술 동향 및 특허 전망

  • Choi, Ji Weon (National Institute of Horticultural and Herbal Science, RDA) ;
  • Kim, Su Yeon (The Foundation of Agricultural Technology Commercialization and Transfer) ;
  • Yu, Go Eun (National Institute of Agricultural Sciences, RDA) ;
  • Kim, Chang Kug (National Institute of Agricultural Sciences, RDA)
  • 최지원 (농촌진흥청 국립원예특작과학원) ;
  • 김수연 (농업기술실용화재단) ;
  • 유고은 (농촌진흥청 국립농업과학원) ;
  • 김창국 (농촌진흥청 국립농업과학원)
  • Received : 2019.01.30
  • Accepted : 2019.03.27
  • Published : 2019.04.30
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Abstract

Background: Medicinal plants are widely used in Asia. They have proven to be an invaluable asset in modern drug discovery and their demand has been steadily increasing across various industries. Methods and Results: Using 4,867 valid patents related to 12 oriental medicinal plants of 10 country groups, the growth and development potential of patents was evaluated. The cites per patent (CPP) and patent family size (PFS) indices were used to evaluate the market capability and technological level of the collected patents. Meanwhile, the patent impact index (PII) and technology strength (TS) were used to compare the technological competitiveness of patents among various technology types and markets. Both CPP and PFS indices showed that magnolia-vine and balloon flower have numerous core or original patents. Furthermore, an increase in both PII and TS indices was observed. A newly designed intellectual property multi-layer (IPM) model predicted that the medicine, genome and cosmetic categories have a high possibility of patent application growth. Conclusions: The IPM model can be used to provide the scope of particular technology fields for patent development. In addition, this study can assist patents to advance in the international market and guide the development of a national industrial strategy.

Keywords

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Fig. 1. Landscape of technologies related to two medicinal plants based on the IPP model of magnolia-vine (A) and balloon flower (B).

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Fig. 2. IPE model landscape of the potential for technology development based on magnolia-vine (A) and balloon flower (B).

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Fig. 3. The graph shows the distribution of technologicallevels and market power based on the CPP and PFSindices for the 12 medicinal plants.

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Fig. 4. Radar chart of the relative Likert scale [0 (lowest) to 5 (highest)] with three technical factors (i.e., blank technology, entry barrier, and future growth).

Table 1. Classification of effective patents between 12 medicinal plants and 10 country groups.

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Table 2. Classification of the number of patents, patent impact index (PII), and technology strength (TS) index in two intervals for the 12medicinal plants.

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References

  1. Amaral LFG and Fierro IM. (2013). Profile of medicinal plants utilization through patent documents: The andiroba example. Revista Brasileira de Farmacognosia. 23:716-722. https://doi.org/10.1590/S0102-695X2013005000046
  2. Chen DZ, Lin WY and Huang MH. (2007). Using essential patent index and essential technological strength to evaluate industrial technological innovation competitiveness. Scientometrics. 71:101-116. https://doi.org/10.1007/s11192-007-1655-6
  3. Choi SC, Yoon JH, Kim KS, Lee JY and Kim CH. (2011). SAO network analysis of patents for technology trends identification: A case study of polymer electrolyte membrane technology in proton exchange membrane fuel cells. Scientometrics. 88:863-883. https://doi.org/10.1007/s11192-011-0420-z
  4. Choi SW, You YY and Na KS. (2014). Forecasting promising technology using analysis of patent information: Focused on next generation mobile communications. Journal of Central South University. 21:4303-4310. https://doi.org/10.1007/s11771-014-2429-y
  5. Endresen A and Janda LA. (2015). Five statistical models for likert-type experimental data on acceptability judgments. Equinoxonline. 3:217-250.
  6. Evans BJ. (2009). Seven pillars of a new evidentiary paradigm: The food, drug, and cosmetic act enters the genomic era. Notre Dame Low Review. 85:419-524.
  7. Fang R. (2003). Modern western medicine as standard for traditional chinese medicine: A critical appraisal. Journal of Law Medicine and Ethics. 31:213-221. https://doi.org/10.1111/j.1748-720X.2003.tb00082.x
  8. Felix R and Roy S. (2014). Impact of financial crisis in Asia. Procedia-Social and Behavioral Sciences. 133:336-345. https://doi.org/10.1016/j.sbspro.2014.04.199
  9. Food and Agriculture Organization(FAO). (2018). Global tea consumption and production driven by robust demand in China and India. Food and Agriculture Organization. Roma, Italy. http://www.fao.org/china/news/detail-events/en/c/1136478/(cited by 2019 May 17).
  10. Grimaldi M, Cricelli L, Di Giovanni M and Rogo F. (2015). The patent portfolio value analysis: A new framework to leverage patent information for strategic technology planning. Technological Forecasting and Social Change. 94:286-302. https://doi.org/10.1016/j.techfore.2014.10.013
  11. Han YJ. (2010). China's transition into innovation-driven economy: Focus on patent analysis of individual actors. International Area Studies Review. 14:349-372. https://doi.org/10.18327/jias.2010.04.14.1.349
  12. Harhoff D, Scherer FM and Vopel K. (2003). Citations, family size, opposition and the value of patent rights. Research Policy. 32:1343-1363. https://doi.org/10.1016/S0048-7333(02)00124-5
  13. Hicks D, Breitzman T, Olivastro D and Hamilton K. (2001). The changing composition of innovative activity in the US-a portrait based on patent analysis. Research Policy. 30:681-703. https://doi.org/10.1016/S0048-7333(00)00147-5
  14. Hsiao JIH. (2007). Patent protection for Chinese herbal medicine product invention in Taiwan. Journal of World Intellectual Property. 10:1-21. https://doi.org/10.1111/j.1422-2213.2007.00311.x
  15. Huang Z, Chen H, Yip A, Ng G, Guo F, Chen ZK and Roco MC. (2003). Longitudinal patent analysis for nanoscale science and engineering: Country, institution and technology field. Journal of Nanoparticle Research. 5:333-363. https://doi.org/10.1023/A:1025556800994
  16. Intellectual Property India(IPI). (2018). Intellectual Property India. http://ipindia.gov.in/ (cited by 2019 May 17).
  17. Iwase S, Yamaguchi T, Miyaji T, Terawaki K, Inui A and Uezono Y. (2012). The clinical use of Kampo medicines(traditional Japanese herbal treatments) for controlling cancer patients' symptoms in Japan: A national cross-sectional survey. BMC Complementary and Alternative Medicine. 12:222. https://doi.org/10.1186/1472-6882-12-222 (cited by 2019 May 24).
  18. Japan Patent Office(JPO). (2018). Japan Patent Office. https://www.jpo.go.jp/ (cited by 2019 May 17).
  19. Kahler M. (2013). Economic crisis and global governance: The stability of a globalized world. Procedia-Social and Behavioral Sciences. 77:55-64. https://doi.org/10.1016/j.sbspro.2013.03.062
  20. Kim D, Ahn M, Jung J, Kwon S, Park EJ, Koo KH and Woo JM. (2015). Perspectives on the market globalization of Korean herbal manufacturers: A company-based survey. Evidence-Based Complementary and Alternative Medicine. 2015:515328. http://dx.doi.org/10.1155/2015/515328 (cited by 2019 May 17).
  21. Kim NS, Choi DJ, Choi EJ, Lee JH, Park S, Lee YS, Lee JW, Lee DY, Kim GS and Lee SE. (2018). Screening and evaluation of the anti-allergic effect of Korean medicinal plant extracts. Korean Journal of Medicinal Crop Science. 26:42-54. https://doi.org/10.7783/KJMCS.2018.26.1.42
  22. Korea Institute of Patent Information(KIPI). (2005). Patent analysis methodology for creating technology roadmap. Korea Institute of Patent Information. Daejeon, Korea. p.1-254.
  23. Korean Intellectual Property Rights Information Service (KIPRIS). (2018). Korean Intellectual Property Rights Information Service. http://www.kipris.or.kr/ (cited by 2019 May 24).
  24. Korean Statistical Information Service(KOSIS). (2018). Korean Statistical Information Service. http://kosis.kr/ (cited by 2019 May 10).
  25. Kumar S. (2005). Exploratory analysis of global cosmetic industry: Major players, technology and market trends. Technovation. 25:1263-1272. https://doi.org/10.1016/j.technovation.2004.07.003
  26. Lin AX, Chan G, Hu Y, Ouyang D, Ung COL, Shi L and Hu H. (2018). Internationalization of traditional Chinese medicine: Current international market, internationalization challenges and prospective suggestions. Chinese Medicine. 13:9. https://doi.org/10.1186/s13020-018-0167-z (cited by 2019 May 17).
  27. Lin BW, Chen CJ and Wu HL. (2006). Patent portfolio diversity, technology strategy, and firm value. IEEE Transactions on Engineering Management. 53:17-26. https://doi.org/10.1109/TEM.2005.861813
  28. Lu Y, Hernandez P, Abegunde D and Edejer T. (2011). The world medicines situation 2011. Medicine expenditures World Health Organization. https://www.who.int/medicines/areas/policy/world_medicines_situation/WMS_ch6_wPricing_v6.pdf (cited by 2019 May 10).
  29. Ministry of Law and Human Rights of Indonesia(MLHR). (2018). Directorate general of intellectual property(DGIP). http://www.dgip.go.id/ (cited by 2019 May 17).
  30. National Development and Reform Commission(NDRC). (2016). The 13th five-year plan for economic and social development of the people's republic of China. http://en.ndrc.gov.cn/newsrelease/201612/P020161207645765233498.pdf (cited by 2019 May 17).
  31. National Office of Intellectual Property of Vietnam(NOIP). (2018). National office of intellectual property. http://www.noip.gov.vn/ (cited by 2019 May 17).
  32. Pan SY, Chen SB, Dong HG, Yu ZL, Dong JC, Long ZX, Fong WF, Han YF and Ko KM. (2011). New perspectives on Chinese herbal medicine(Zhong-Yao) research and development. Evidence-Based Complementary and Alternative Medicine. 2011:403709. http://dx.doi.org/10.1093/ecam/neq056 (cited by 2019 May 24).
  33. Patent Cooperation Treaty(PCT). (2018). Patent cooperation treaty.http://www.wipson.com/ (cited by 2018 May 17).
  34. Sahoo N, Manchikanti P and Dey SH. (2011). Herbal drug patenting in India: IP potential. Journal of Ethnopharmacology. 137:289-297. https://doi.org/10.1016/j.jep.2011.05.022
  35. Sato-Masumoto N, Uchikura T, Sugiwaki H, Yoshimura M, Masada S, Atsumi T, Watanabe M, Tanaka N, Uchiyama N, Amakura Y and Hakamatsuka T. (2017). Survey on the original plant species of crude drugs distributed as Cynanchi Wilfordii radix and its related crude drugs in the Korean and Chinese markets. Biological and Pharmaceutical Bulletin. 40:1693-1699. https://doi.org/10.1248/bpb.b17-00226
  36. Seong BJ, Kim SI, Jee MG, Kim SD, Kwon AR, Kim HH, Won JY and Lee KS. (2018). Antioxidative activity and inhibition of angiotensin converting enzyme by Lycii fructus extracts prepared by adding white ginseng and red ginseng. Korean Journal of Medicinal Crop Science. 26:370-381. https://doi.org/10.7783/KJMCS.2018.26.5.370
  37. Serafini MR, Guimaraes AG, Quintans-Junior LJ, Nunes PS, Matos IG, Sravanan SS and de Souza AAA. (2014). Recent patents on medicinal plants/natural products as a therapeutic approach to wounds and burns healing. Recent Patents on Biotechnology. 8:231-239. https://doi.org/10.2174/187220830803150605164205
  38. Smith Richard D, Carlos C and Oh C. (2009). Trade, TRIPS, and pharmaceuticals. The Lancet. 373:684-691. https://doi.org/10.1016/S0140-6736(08)61779-1
  39. State Intellectual Property Office(SIPO). (2018). State intellectual property office. http://english.sipo.gov.cn/ (cited by 2018 May 17).
  40. Sullivan GM and Artino Jr AR. (2013). Analyzing and interpreting data from likert-type scales. Journal of Graduate Medical Education. 5:541-542. https://doi.org/10.4300/JGME-5-4-18
  41. Taiwan Intellectual Property Office(TIPO). (2018). Taiwan intellectual property office. https://www.tipo.gov.tw/ (cited by 2018 May 17).
  42. Timmermans S and Berg M. (2003). The practice of medical technology. Sociology of Health and Illness. 25:97-114. https://doi.org/10.1111/1467-9566.00342
  43. World Intellectual Property Organization(WIPO). (2018). World intellectual property organization. http://www.wipo.int/ (cited by 2018 May 17).
  44. Worldwide Intellectual Property Service(WIPS). (2018). Worldwide intellectual property service. http://www.wipson.com/ (cited by 2018 May 17).
  45. Wu H and Leung SO. (2017). Can likert scales be treated as interval scales?-a simulation study. Journal of Social Service Research. 43:527-532. https://doi.org/10.1080/01488376.2017.1329775
  46. Yoon JY, Ryu TK and Yoon JH. (2012). A study on patent indexes for characteristics analysis of IP portfolios. Journal of Information Management. 43:67-83. https://doi.org/10.1633/JIM.2012.43.2.067
  47. Yu N, Wei Yl, Zhu Y, Zhu N, Wang Yl, Zhang HP and Sun AD. (2018). Integrated approach for identifying and evaluating the quality of Marsdenia tenacissima in the medicine market. PLoS One. 13:e0195240. https://doi.org/10.1371/journal.pone.0195240 (cited by 2019 May 17).
  48. Yun IS, Kim SJ and Jeong ES. (2011). Evaluation of technology activity, innovation and productivity using Korean patent information. Journal of Information Management. 42:151-165. https://doi.org/10.1633/JIM.2011.42.2.151