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신경 손상 후 환측의 동작분석을 통한 충격파가 신경재생에 미치는 영향

Impact of Shock Wave on Nerve Regeneration in Motion Analysis of Affected Side after Nerve Injury

  • 투고 : 2018.12.13
  • 심사 : 2019.02.26
  • 발행 : 2019.03.31

초록

본 연구는 체외 충격파 치료를 이용하여 신경 손상 흰쥐의 신경재생에 미치는 영향을 알아보았다. 본 연구에서는 체중이 230~280g고 생후 6주의 Sprague-Dawley계 수컷 흰쥐 30마리를 사용하였다. 무작위 추출방법을 이용하여 좌골신경 손상 후 체외 충격파 치료를 받는 실험군(n=15)과 좌골신경 손상 후 체외 충격파 치료를 받지 않는 대조군(n=15)으로 나누어 실험을 실시하였다. 본 연구에서 체외충격파 치료를 적용하기 위해서 체외 충격파 치료기(OPTIMUS, SALUS TALENT 3, Korea)를 이용하였으며 낮은 출력(low intensity)을 이용하여 오른쪽 후지의 좌골신경 압좌 부위에 적용하였다. 본 연구에서는 다트피쉬 소프트웨어를 이용하여 환측 후지의 입각기 시간과 보폭거리를 측정하였다. 환측 후지의 입각기 시간과 보폭거리의 그룹 간 변화량 비교에서 체외 충격파 치료를 적용한 실험군과 체외 충격파 치료를 적용하지 않은 대조군 사이에는 통계학적으로 유의한 차이가 있었다. 결론적으로 체외 충격파 치료는 신경재생에 긍정적인 영향을 미친다.

This study investigated the effect of extracorporeal shock wave therapy on nerve regeneration in nerve injured rats. In this study, we used 30 male Sprague-Dawley rats weighing 230-280g and 6 weeks old. Study groups were divided into two groups using a random sampling method: experimental group (n=15) treated with extracorporeal shock wave after sciatic nerve injury and control group (n=15) treated without extracorporeal shock wave after sciatic nerve injury. In this study, extracorporeal shock wave therapy equipment (OPTIMUS, SALUS TALENT 3, Korea) was used to apply extracorporeal shock wave therapy and applied to the sciatic nerve crush area of the right hind limb using low intensity. We measured the stance time and stride distance of the affected side using dartfish software. There was a statistically significant difference in the change of stance time and stride distance of the affected side between the experimental group using extracorporeal shock wave therapy and the control group without extracorporeal shock wave treatment. In conclusion, extracorporeal shock wave therapy has a positive effect on nerve regeneration.

키워드

참고문헌

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