수종의 수산화칼슘 근관 첩약제와 레진계 근관 실러의 사용 후 통증 발생 빈도에 관한 연구

Comparison of the Frequency of Pain Occurrence by Using Different Calcium Hydroxide Pastes and Root Canal Sealers

  • 곽상원 (부산대학교 치의학전문대학원 치과보존학교실) ;
  • 김현철 (부산대학교 치의학전문대학원 치과보존학교실)
  • Kwak, Sang Won (Department of Conservative Dentistry, School of Dentistry, Pusan National University, Dental Research Institute) ;
  • Kim, Hyeon-Cheol (Department of Conservative Dentistry, School of Dentistry, Pusan National University, Dental Research Institute)
  • 투고 : 2018.02.12
  • 심사 : 2018.03.26
  • 발행 : 2018.05.01

초록

Objectives: This study aimed to compare the postoperative pain and clinical performance after applying three different intracanal medicaments and root canal sealers. Materials and Methods: Sixty-five patients requiring root canal treatment due to symptomatic apical periodontitis were included in this study. After a glide path preparation by using PathFile, each canal was shaped with ProTaper Next file system. After the canal cleaning and shaping procedure, the canal was dried and each intracanal medicaments were adjusted (Calcipex II, TRC-paste, Metapaste). At the next visit, the patients were requested to answer the absence of the pain after the procedure. Once the patients showed no symptom, the canal was obturated with each corresponded root canal sealers (AH plus, Radic-sealer, ADseal). The patients were recalled after 1 week, 1, 3, and 6 months to check the postoperative pain or unexpected clinical signs. One-way ANOVA and Duncan's post hoc comparison, and Chi-square test were used for statistical analysis to evaluate any differences among tested materials. Results: The average number of visits for intracanal medication was 2.69, 2.65, and 2.61 for Calcipex II, TRC-paste, and Metapaste. There were no statistically differences in post-obturation pain among three groups obturated with different root canal sealers (P > 0.05). Conclusions: Under the limitations of this study, three tested intracanal medicaments and epoxy resin root canal sealers showed clinically acceptable similar results.

키워드

과제정보

연구 과제 주관 기관 : Pusan National University

참고문헌

  1. Marsh SJ, Largent MD. A bacteriological study of the pulp canals of infected primary molars. J Dent Child 1967; 34(6): 460-70.
  2. Blome B, Braun A, Sobarzo V, Jepsen S. Molecular identification and quantification of bacteria from endodontic infections using real-time polymerase chain reaction. Oral Microbiol Immunol 2008; 23(5): 384-90. https://doi.org/10.1111/j.1399-302X.2008.00440.x
  3. Manzur A, Gonz?lez AM, Pozos A, Silva-Herzog D, Friedman S. Bacterial quantification in teeth with apical periodontitis related to instrumentation and different intracanal medications: a randomized clinical trial. J Endod 2007; 33(2): 114-8. https://doi.org/10.1016/j.joen.2006.11.003
  4. Siqueira JF Jr, Rocas IN. Optimising single-visit disinfection with supplementary approaches: a quest for predictability. Aust Endod J 2011; 37(3): 92?8. https://doi.org/10.1111/j.1747-4477.2011.00334.x
  5. Orucoglu H, Cobankara FK. Effect of unintentionally extruded calcium hydroxide paste including barium sulfate as a radiopaquing agent in treatment of teeth with periapical lesions: Report of a case. J Endod 2008; 34(7): 888-91. https://doi.org/10.1016/j.joen.2008.04.012
  6. Vernieks AA, Messer LB. Calcium hydroxide induced healing of periapical lesions: A study of 78 non-vital teeth. J Br Endod Soc 1978; 11(2): 61-9. https://doi.org/10.1111/j.1365-2591.1978.tb00663.x
  7. Schilder H. Filling root canals in three dimensions. Dent Clin North Am 1967; 723?44.
  8. Gatewood RS. Endodontic materials. Dent Clin North Am 2007; 51(3): 695?712. https://doi.org/10.1016/j.cden.2007.04.005
  9. Ardila CN, Wu MK, Wesselink PR. Percentage of filled canal area in mandibular molars after conventional root-canal instrumentation and after a noninstrumentation technique (NIT). Int Endod J 2003; 36(9): 591?8. https://doi.org/10.1046/j.1365-2591.2003.00689.x
  10. Jacob GM, Kumar A, Varughese JM, Varghese NO, Harikrishna Varma PR, Komath M. Periapical tissue reaction to calcium phosphate root canal sealer in porcine model. Indian J Dent Res 2014; 25(1): 22-7. https://doi.org/10.4103/0970-9290.131049
  11. Nair PN. Pathogenesis of apical periodontitis and the causes of endodontic failures. Crit Rev Oral Biol Med. 2004; 15(6): 348-81. https://doi.org/10.1177/154411130401500604
  12. Oliet S. Single-visit endodontics: a clinical study. J Endod 1983; 9(4): 147-52. https://doi.org/10.1016/S0099-2399(83)80036-3
  13. Baraba A, Zeljezic D, Kopjar N, Mladinic M, Anic I, Miletic I. Evaluation of cytotoxic and genotoxic effects of two resin-based root-canal sealers and their components on human leucocytes in vitro. Int Endod J 2011; 44(7): 652?61. https://doi.org/10.1111/j.1365-2591.2011.01869.x
  14. Mestieri LB, Gomes-Cornelio AL, Rodrigues EM, et al. Biocompatibility and bioactivity of calcium silicate-based endodontic sealers in human dental pulp cells. J Appl Oral Sci. 2015; 23(5): 467?71. https://doi.org/10.1590/1678-775720150170
  15. Chang MC, Lin LD, Chen YJ, et al. Comparative cytotoxicity of five root canal sealers on cultured human periodontal ligament fibroblasts. Int Endod J 2010; 43(3): 251?7. https://doi.org/10.1111/j.1365-2591.2009.01676.x
  16. Rodriguez-Lozano FJ, Garcia-Bernal D, Onate-Sanchez RE, Ortolani-Seltenerich PS, Forner L, Moraleda JM. Evaluation of cytocompatibility of calcium silicate-based endodontic sealers and their effects on the biological responses of mesenchymal dental stem cells. Int Endod J 2017; 50(1): 67-76. https://doi.org/10.1111/iej.12596
  17. https://www.dentsply.com/content/dam/dentsply/pim/manufacturer/Endodontics/Obturation/Sealers/AH_Plus___AH_Plus_Jet/AH-Plus-akx2gjascientific-en-1402. Accessed at 2018/1/22.
  18. Flores DS, Rached FJ Jr, Versiani MA, Guedes DF, Sousa-Neto MD, Pecora JD. Evaluation of physicochemical properties of four root canal sealers. Int Endod J 2011; 44(2): 126-35. https://doi.org/10.1111/j.1365-2591.2010.01815.x
  19. De Almeida WA, Leonardo MR, Tanomaru Filho M, Silva LA. Evaluation of apical sealing of three endodontic sealers. Int Endod J 2000; 33(1): 25-7. https://doi.org/10.1046/j.1365-2591.2000.00247.x
  20. Leonardo MR, Bezerra da Silva LA, Filho MT, Santana da Silva. Release of formaldehyde by 4 endodontic sealers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88(2): 221-5. https://doi.org/10.1016/S1079-2104(99)70119-8
  21. Brackett MG, Martin R, Sword J, et al. Comparison of seal after obturation techniques using a polydimethylsiloxane-based root canal sealer. J Endod 2006; 32(12): 1188-90. https://doi.org/10.1016/j.joen.2006.07.009
  22. DiRenzo A, Gresla T, Johnson BR, Rogers M, Tucker D, BeGole EA. Postoperative pain after 1- and 2-visit root canal therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93(5): 605-10. https://doi.org/10.1067/moe.2002.121900
  23. Serper A, Ucer O, Onur R, Etikan I. Comparative neurotoxic effects of root canal filling materials on rat sciatic nerve. J Endod 1998; 24(9): 592?4. https://doi.org/10.1016/S0099-2399(98)80116-7
  24. Ahlgren FK, Johannessen AC, Hellem S. Displaced calcium hydroxide paste causing inferior alveolar nerve paraesthesia: report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003; 96(6): 734-7. https://doi.org/10.1016/j.tripleo.2003.08.018
  25. Byun SH, Kim SS, Chung HJ, et al. Surgical management of damaged inferior alveolar nerve caused by endodontic overfilling of calcium hydroxide paste. Int Endod J 2016; 49(11): 1020-9. https://doi.org/10.1111/iej.12560
  26. Brodin P. Neurotoxic and analgesic effects of root canal cements and pulp-protecting dental materials. Endod Dent Traumatol 1988; 4(1): 1-11. https://doi.org/10.1111/j.1600-9657.1988.tb00284.x
  27. Grossman L. Obturation of root canal. In: Grossman L, ed. Endodontic Practice. 10th ed. Philadelphia, PA: Lea and Febiger; 1982: 297.
  28. Huang FM, Chou MY, Chang YC. Induction of cyclooxygenase-2 mRNA and protein expression by epoxy resin and zinc oxide-eugenol based root canal sealers in human osteoblastic cells. Biomaterials 2003; 24(11): 1869-75. https://doi.org/10.1016/S0142-9612(02)00584-7
  29. Wolf M, Kupper K, Reimann S, Bourauel C, Frentzen M. 3D analyses of interface voids in root canals filled with different sealer materials in combination with warm gutta-percha technique. Clin Oral Investig 2014; 18(1): 155-61. https://doi.org/10.1007/s00784-013-0970-y
  30. Tai KW, Huang FM, Chang YC. Cytotoxic evaluation of root canal filling materials on primary human oral fibroblast cultures and a permanent hamster cell line. J Endod 2001; 27(9): 571-3. https://doi.org/10.1097/00004770-200109000-00004
  31. Zhou HM, Shen Y, Zheng W, Li L, Zheng YF, Haapasalo M. Physical properties of 5 root canal sealers. J Endod 2013; 39(10): 1281-6. https://doi.org/10.1016/j.joen.2013.06.012
  32. Lee JK, Kwak SW, Ha JH, Lee W, Kim HC. Physicochemical Properties of Epoxy Resin-Based and Bioceramic-Based Root Canal Sealers. Bioinorg Chem Appl. 2017; Article ID 2582849:1-8.