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The Korean Ceramic Society (한국세라믹학회)
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Synthesis and Functionalization of Upconversion Nanoparticles for Bioimaging

바이오 이미징을 위한 업컨버전 나노입자(upconversion nanoparticles)의 합성 및 특성화

  • Cho, Hye In (Department of Materials Science and Engineering, Korea University) ;
  • Lee, Jae-Seung (Department of Materials Science and Engineering, Korea University)
  • 조혜인 (고려대학교 신소재공학부) ;
  • 이재승 (고려대학교 신소재공학부)
  • Received : 2018.08.08
  • Accepted : 2018.08.23
  • Published : 2018.09.30
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Abstract

The increasing importance of biomedical imaging technology has led to the development of a variety of luminescent materials, including molecular fluorophores, fluorescent proteins, and quantum dots. Owing to their inherent disadvantages, such as insufficient chemical stability and limited biocompatability, their utilization has been limited with imaging only under highly optimized and controlled conditions. Recently, a new class of luminescent nanoparticles, upconversion nanoparticles (UCNPs), have been emerging as a practically useful nanoprobe for various bioimaging applications. The detailed synthesis, functionalization, properties and in-vitro / in-vivo applications of the UCNPs are introduced and discussed in this Review.

Keywords

References

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