Abstract
Purpose : We identified correlation between macular thickness and RNFL (retina nerve fiber layer) measured by OCT and axial length in Korean children divided as three groups according to refractive errors. Methods : In total, 134 eyes of 67 Korean children who experienced no eye disease and ophthalmology surgery were involved in this study and then divided as three groups such as hyperopic, emmetropic and myopic groups. Macular thickness and RNFL thickness were measured with Cirrus HD-OCT, and axial length was done with IOL Master.Macular thickness and RNFL thickness were measured by Cirrus HD-OCT, and axial length using IOL Master. Correlation between axial length and retinal thickness in three groups according to refractive errors was investigated. Results : The type of refractive error measured by axial length was myopic, emmetropic and hyperopic groups in order, showing significant difference (p<0.05). The center thickness of macular was myopic, emmetropic and hyperopic groups in order, showing significant difference(p<0.05). The thicknesses of superior, nasal and inferior regions in peripheral macula were the thinnest in myopic group (p<0.05). It was shown that positive correlation was found between the center thickness of macula and axial length (r=0.283, p<0.05), while negative correlation was found between the peripheral thickness of RNFL and axial length. The temporal thickness of RNFL represented the thickest in myopic group, showing positive correlation with axial length(r=0.39, p<0.05). The superior, nasal and inferior thickness of RNFL represented negative correlation with axial length, showing statistically significant in the nasal thickness of RNFL(r=-0.23, p<0.05). Conclusion : Through this study, we identified correlation between macular thickness, the thickness of RNFL and axial length using OCT in Korean children, and also found the differences in three refractive error groups.
목적 : 굴절이상별 세 그룹으로 분류한 우리나라 아동들의 안축장과 빛간섭단층촬영(OCT)로 측정한 황반두께, 망막신경섬유층두께 사이의 상관성을 알아보고자 하였다. 방법 : 안질환이 없고 안과관련 수술 경험이 없는 아동 67명(134안)을 대상으로 원시, 정시, 근시 그룹으로 분류하였다. 황반부와 망막신경섬유층두께는 Cirrus HD-OCT를 이용하여 측정하였고, 안축장은 IOL Master를 이용하여 측정하였다. 결과 : 안축장은 근시, 정시, 원시그룹 순서로 길게 측정되었다(p<0.05). 중심부황반의 두께는 근시, 정시, 원시그룹 순서로 두껍게 측정되었다(p<0.05). 주변부황반부는위쪽, 코쪽, 아래쪽부분에서 근시그룹이 가장 얇았다(p<0.05).황반의 중심부 두께는 안축장과 양의 상관관계가 있었다(r=0.283, p<0.05). 주변부 황반의 두께는 모두 안축장과 음의 상관관계를 보였다. 귀쪽망막신경섬유층두께(Temporal RNFL Thickness)는 근시그룹이 가장 두꺼운 결과를 보였고,안축장과통계적으로 유의한 양의상관성이 나타났다(r=0.39, p<0.05). 위쪽과 코쪽, 아래쪽의 망막신경섬유층 두께는 안축장과 모두 음의 상관성을 나타냈다. 코쪽 부분의 두께는 통계적으로 유의하게 나타났다(r=-0.23, p<0.05). 결론 : 본 연구를 통해 우리나라 소아들의 OCT로 측정한 망막의 황반부의 두께, 망막신경섬유층의 두께와 안축장은 근시의 정도가 높을수록 안축장의 길이가 더 길게 측정되었으며, 굴절이상별 세 그룹에서 나타나는 차이점을 확인하였다.