Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
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Proton therapy: Literature review of clinical effectiveness as an advanced convergent cancer therapy

양성자 치료: 융복합 첨단 암 치료로서의 임상적 유효성에 대한 문헌 고찰

  • Park, Hyojung (Department of Radiation Oncology, Dankook University Hospital)
  • 박효정 (단국대학교 의과대학 부속 병원 방사선종양학과)
  • Received : 2018.08.17
  • Accepted : 2018.10.20
  • Published : 2018.10.28
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Abstract

This study was conducted to evaluate the clinical effectiveness of proton therapy as an advanced convergent cancer therapy. Clinical data of proton therapy were analyzed. As proton enters patient's body, it releases low dose of energy and shows an increasing energy deposition as it reaches certain point unlike x-ray. It may therefore reduce the radiation dose to the normal tissues in front and beyond the lesion and minimize the radiation damage. Proton therapy is expected to improve clinical outcomes and reduce treatment related toxicities. It is used in various cancers. Further studies are necessary.

본 연구는 융복합 첨단 암 치료 방법인 양성자 치료의 특징 및 임상적 유효성에 대해 알아보고자 하였다. 양성자 치료의 임상 자료를 분석하였다. 양성자는 기존 X선과 달리 몸을 통과할 때 적은 에너지를 방출하면서 물체에 에너지를 전달하다 일정 지점에 접근하면서 에너지 축적이 증가하면서 최대 에너지를 전달한다. 이러한 물리적 특징으로 인해 병변 앞쪽과 뒤쪽의 정상 조직에 조사되는 방사선량을 줄이고 이로 인해 발생할 수 있는 방사선 손상을 최소화할 수 있다. 양성자 치료로 임상 결과의 향상과 치료 관련 부작용의 감소를 기대할 수 있다. 현재 양성자 치료는 다양한 암에서 사용되고 있으며 임상 결과를 축적해 가고 있다. 향후 기술 및 관련 학문의 추가 연구가 필요하다.

Keywords

References

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