References
- Korea Agro-Fisheries & Food Trade Corporation (2016) Customized survey on agricultural product market. Product: Ginseng), Country: Hong Kong. (http://www.kati.net/board/report)
- Chan, T. W., Cheng, S. W., Kwok, I. M., Lau, F. W. and Xu H. X. (2000) Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS. Anal. Chem. 72: 1281-1287. https://doi.org/10.1021/ac990819z
- Jia, L., Zhao, Y. and Liang, X. J. (2009) Current evaluation of the millennium phytomedicine- ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine. Curr. Med. Chem. 16: 2924-2942. https://doi.org/10.2174/092986709788803204
- Yan, J., Engle, V. F., He, Y., Jiao, Y. and Gu, W. (2009) Study designs of randomized controlled trials not based on Chinese medicine theory are improper. Chinese Medicine 4: 3. https://doi.org/10.1186/1749-8546-4-3
- Wang, L. C. and Lee, T. F. (2000) Effect of ginseng saponins on cold tolerance in young and elderly rats. Planta. Med. 66: 144-147. https://doi.org/10.1055/s-2000-11122
- Hsu, P. (1979) Why Chinese prefer American ginseng and how they use it. Proceeding of the first National Ginseng Conference. 104-106.
- Mora Marco, J. (1998) The Complete Ginseng Handbook: A Practical Guide for Energy, Health, and Longevity. Contemporary Books. 1st edition.
- Conkling, W. (1999) Secrets of Ginseng: Learn about Nature's Amazing Energy Herb!, St. Martin's Paperbacks, 1st edition.
- Lee, D. P. (2006) A study on the cooling effect claim & development procedure of American ginseng. J. Ginseng Res. 30: 158-164. https://doi.org/10.5142/JGR.2006.30.3.158
- Zhang, S. C. (1991) Chinese Ginseng. Shanghai Science & Education Press Co, Chinese. 373-384.
- Park, E. Y., Kim, M. H., Kim, E. H., Lee, E. K., Park, I. S., Yang, D. C. and Jun, H. S. (2014) Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters. Am. J. Chin. Med. 42: 173-187. https://doi.org/10.1142/S0192415X14500128
- Ang-Lee, M. K., Moss, J. and Yuan, C. S. (2001) Herbal medicines and perioperative care. JAMA 286: 208-216. https://doi.org/10.1001/jama.286.2.208
- Yun, T. K. (2001) Brief introduction of Panax ginseng C.A. Meyer. J. Korean Med. Sci. 16: Suppl: S3-5. https://doi.org/10.3346/jkms.2001.16.S.S3
- Yuan, C. S., Wei, G., Dey, L., Karrison, T., Nahlik, L., Maleckar, S., Kasza, K., Ang-Lee, M. and Moss, J. (2004) Brief communication: American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled Trial. Ann. Intern. Med. 141: 23-27. https://doi.org/10.7326/0003-4819-141-1-200407060-00011
- Yuan, C. S., Wang, C. Z., Wicks, S. M. and Qi, L. W. (2010) Chemical and pharmacological studies of saponins with a focus on American ginseng. J. Ginseng Res. 34: 160-167. https://doi.org/10.5142/jgr.2010.34.3.160
- Choi, J., Kim, T. H., Choi, T. Y. and Lee, M. S. (2013) Ginseng for health care: a systematic review of randomized controlled trials in Korean literature. PLoS One 8: e59978. https://doi.org/10.1371/journal.pone.0059978
- Lee, N. H. and Son, C. G. (2011) Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng. J. Acupunct. Meridian. Stud. 4: 85-97. https://doi.org/10.1016/S2005-2901(11)60013-7
- Kim, Y. S., Woo, J. Y., Han, C. K. and Chang, I. M. (2015) Safety analysis of Panax ginseng in randomized clinical trials: A Systematic Review. Medicines (Basel). 2: 106-126.
- Kim J. Y. (2009) Sasang constitutional medicine as a holistic tailored medicine. Evid. Based Complement Alternat. Med. 6: 11-19.
- Shim, E. B., Lee, S., Kim, J. Y. and Earm, Y. E. (2008) Physiome and Sasang constitutional medicine. J. Physiol. Sci. 58: 433-440. https://doi.org/10.2170/physiolsci.RV004208
- Nam, K. Y. (1996) Contemporary Korean Ginseng(chemical constituents and pharmacological activity). Korean Ginseng & Tobacco Research Institute. 158-199.
- Lee, F. C, Nam, K. Y. and Kim, S. K. (1983) An Introduction to Korean Ginseng (The Elixirof Life). Korean Ginseng & Tobacco Research Institute Daejon, Korea 17-24.
- Choi, D. J., Cho, K. H., Jung, W. S, Park, S. U., Han, C. H, and Lee, W. C. (2006) Clinical effects of Korean ginseng, Korean red ginseng, Chinese ginseng, and American ginseng on blood pressure in mild hypertensive Subjects. Journal of Oriental Medicine 27: 198-208.
- Lee, E. J., Koh, B. H., Nam, K. Y. and Song, I. B. (1998) Clinical study on effects of Korean red ginseng from Sasang constitution in healthy adults. Proceeding of 2nd Oriental Medicine Hospital Symposium 213-244.
- Lee, S. Y. and Hang, M. W. (2013) A case study of a soyangin patient with palpitation and epistaxis that occurred after taking Panax ginseng. J. Sasang Constitut. Med. 25: 406-413. https://doi.org/10.7730/JSCM.2013.25.4.406
- Choi, M. S, Jeong, J. C., Park, J. K., Ahn, H. Y. and Kim, D. I. (2009) A study on thermal effect and medication compliance of red ginseng extract. Journal of Korean Obstetrics and Gynecology 22: 223-235.
- Jin, E., Shi, Z. X., Ke, Y. N., Huang, L. H., Yan, X. P., Wei, Y. L., Liu, P., Lee, K. S., Nam, K. Y. and Kumagai, A. (1997) Effects of Korean red ginseng in the treatment of hyperlipidemic patients. Proc. of '97 Korea-Japan Ginseng Symp, Korea Ginseng & Tobacco Research Institute, Korea. 82-90.
- Jin, E. Y., Li., Y. J., Yang, L. X., Jin, M., Wei, Y. L. and Nam, K. Y. (2002) Effect of Korea red ginseng on the symptoms and hemodynamics in healthy elders. Proceedlings of the International Symposium on Ginseng. The Society of Ginseng. 27-34.
- Soldati, F. (1984) Toxicological studies on ginseng. Proc. of the 4th Int'l Ginseng Symp. 119-126.
- Carabin, I. G., Burdock, G. A. and Chatzidakis, C. (2000) Safety assessment of Panax ginseng. Int. J. Toxicol. 19: 293-301. https://doi.org/10.1080/10915810050202105
- Hess, J. R., Parent, R. A., Stevens, K. R., Cox, G. E. and Becci, P. J. (1983) Effects of subchronic feeding of ginseng extract G115 in beagle dogs. Food Chem. Toxicol. 21: 95-97. https://doi.org/10.1016/0278-6915(83)90275-2
- Park, S. J., Lee, J. R., Jo, M. J., Park, S. M., Ku, S. K. and Kim, S. C. (2013) Protective effects of Korean red ginseng extract on cadmium-induced hepatic toxicity in rats. J. Ginseng Res. 37: 37-44. https://doi.org/10.5142/jgr.2013.37.37
- Liu, J. P., Lu, D., Nicholson, R. C., Li, P. Y. and Wang, F. (2011) Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: a 26-week intramuscular repeated administration study in Beagle dogs. Food Chem. Toxicol. 49: 1718-1727. https://doi.org/10.1016/j.fct.2011.04.017
- Liu, J. P., Lu, D., Nicholson, R. C., Zhao, W. J., Li, P. Y. and Wang, F. (2012) Toxicity of a novel anti-tumor agent 20(S)- ginsenoside Rg3: a 26-week intramuscular repeated administration study in rats. Food Chem. Toxicol. 50: 3388-3396. https://doi.org/10.1016/j.fct.2012.07.004
- Lu, D., Liu, J., Zhao, W. and Li, P. (2012) Chronic toxicity of ginsenoside Re on Sprague-Dawley rats. J. Ethnopharmacol. 144: 656-663. https://doi.org/10.1016/j.jep.2012.10.007
- Program, N. T. (2011) Toxicology and carcinogenesis studies of ginseng (CAS No. 50647-08-0) in F344/N rats and B6C3F1 mice (gavage studies). Natl. Toxicol. Program Tech. 1-149.
- Chang, Y. S., Lee, J. Y. and Kim, C. W. (1978) The effect of ginsenoside triol on the postoperative recovery in gynecological patients. Obstetrics & Gynecology Science 21: 253-257.
- Kaneko, H. (1979) Clinical effects of Korean red ginseng powder: double blind clinical trial. Linshiou & Kenkyu 56: 188-195.
- Kaneko, H., Matsuhara, H. and Uchida, M. (1983) Effects of Korean red ginseng powder on the treatment of cerebellar arteriosclerotic patients. Linshiou & Kenkyu 60: 170-176.
- Yamamoto, M, Uemura, Y. and Uemiya, M. (1983) Cinical effects of Korean red ginseng capsule on the treatment of diabetic patients. Kisho & Linshiou 17: 169-177.
- Yoshita, Y., Kamiyama, T. and Izumi, R. (1982) Cinical effects of Korean Red Ginseng capsule on the treatment of diabetic patients. Kisho & Linshiou 16: 302-308.
- Imamura, Y. and Kuwashima, K. (1988) The effects of red ginseng on blood pressure and the quality of life in essential hypertensives. The 5th Int'l Ginseng Symp, Korea Ginseng & Tobacco Research Institute, Korea. 87-91.
- Han, K. H., Choe, S. C., Kim, H. S., Sohn, D. W., Nam, K. Y., Oh, B. H., Lee, M. M., Park, Y. B., Choi, Y. S. and Seo, J. D. (1998) Effect of red ginseng on blood pressure in patients with essential hypertension and white coat hypertension. Am. J. Chin. Med. 26: 199-209. https://doi.org/10.1142/S0192415X98000257
- Yamamoto, M. (1990) Effect of Korean red ginseng on blood pressure (multicentric study). The Ginseng Review 9: 15-20.
- Siegel, R. K. (1979) Ginseng abuse syndrome. Problems with the panacea. JAMA 241: 1614-1615. https://doi.org/10.1001/jama.1979.03290410046024
- Nam, K. Y., Yang, B. W., Shin, W. S. and Park, J. D. (2017) Toward a more complete understanding of the effects of Korean ginseng (Panax ginseng) on blood pressure. Kor. J. Pharmacogn. 48: 97-107.
- Gillis, C. N.(1997) Panax ginseng Pharmacology: A nitric oxide link? Biochemical Pharmacology 54: 1-8. https://doi.org/10.1016/S0006-2952(97)00193-7
- Nam, K. Y. and Park, J. D.(2000). Usage and dosage of ginseng radix( Panax ginseng C. A. Meyer) Based upon traditional and recent scientific clinical applications. Journal of Ginseng Research 26: 99-105.
- Scaglione, F., Cattaneo, G., Alessandria, M. and Cogo, R. (1996) Efficacy and safety of the standarized ginseng extract G115 for potentiating vaccination against common cold and /or influenza syndrome. Drugs Exptl. Clin. Res. 22: 65-72.
- Coon, J. T. and Ernst, E. (2002) Panax ginseng: a systematic review of adverse effects and drug interactions. Drug Saf. 25: 323-344. https://doi.org/10.2165/00002018-200225050-00003
- Ernst, E. (2010) Panax ginseng: an overview of the clinical evidence. Journal of Ginseng Research 34: 259-263. https://doi.org/10.5142/jgr.2010.34.4.259
- Paik, D. J. and Lee, C. H. (2015) Review of cases of patient risk associated with ginseng abuse and misuse. J. Ginseng Res. 39: 89-93. https://doi.org/10.1016/j.jgr.2014.11.005
- Xiang, Y. Z., Shang, H. C., Gao, X. M. and Zhang, B. L. (2008) A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials. Phytother. Res. 22: 851-858. https://doi.org/10.1002/ptr.2384
- Associated Ginseng Growers of Brith Columbia (1988), Assessment of the market potential for ginseng cultivated in B.C. 12-17
- American Botanical Council (ABC) (2003) The ABC clinical guide to herbs ( Ginseng, American): 203-209.
- Province of British Columbia, Ministry of Agricultural and Fisheries(1990), American Ginseng Culture in the Arid Climates of B.C.: 1.
- Qi, L. W., Wang, C. Z. and Yuan, C. S. (2011) Ginsenosides from American ginseng: chemical and pharmacological diversity. Phytochemistry 72: 689-699. https://doi.org/10.1016/j.phytochem.2011.02.012
- Chen, C. F., Chiou, W. F. and Zhang, J. T. (2008) Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium. Acta Pharmacol. Sin. 29: 1103-1108. https://doi.org/10.1111/j.1745-7254.2008.00868.x
- Sievenpiper, J. L., Arnason, J. T., Leiter, L. A. and Vuksan, V. (2003) Variable effects of American ginseng: a batch of American ginseng (Panax quinquefolius L.) with a depressed ginsenoside profile does not affect postprandial glycemia. Eur. J. Clin. Nutr. 57: 243-248. https://doi.org/10.1038/sj.ejcn.1601550
- Wan, J. Z. and Luo, S. W. (1998) The differences of Panax ginseng and Panax quinquefolium in chemical components, pharmacological actions and clinical application. Chin. Herb Med. 29: 57-58.
- Luo, J. Z. and Luo, L. (2009) Ginseng on hyperglycemia: effects and mechanisms. Evid. Based Complement Alternat. Med. 6: 423-427. https://doi.org/10.1093/ecam/nem178
- De Souza, L. R., Jenkins, A. L., Sievenpiper, J. L., Jovanovski, E., Rahelic, D. and Vuksan, V. (2011) Korean red ginseng (Panax ginseng C. A. Meyer) root fractions: differential effects on postprandial glycemia in healthy individuals. J. Ethnopharmacol. 137: 245-250. https://doi.org/10.1016/j.jep.2011.05.015
- Stavro, P. M., W. M. and Vuksan, V. (2004) Korean red ginseng lowers blood pressure in individuals with hypertension. Am. J. Hypertens. 17: S33.
- Lu, J. M., Yao, Q. and Chen, C. (2009) Ginseng compounds: an update on their molecular mechanisms and medical applications. Curr. Vasc. Pharmacol. 293-302.
- Shibata, S. (2001) Chemistry and cancer preventing activities of ginseng saponins and some related triterpenoid compounds. J. Korean Med. Sci. 16: Suppl: S28-S37. https://doi.org/10.3346/jkms.2001.16.S.S28
- Chu, S. F. and Zhang, J. T. (2009) New achievements in ginseng research and its future prospects. Chin. J. Integr. Med. 15: 403-408. https://doi.org/10.1007/s11655-009-0403-6
- Chen, Y., Zhao, Z., Chen, H., Yi, T., Qin, M. and Liang, Z. (2015) Chemical differentiation and quality evaluation of commercial Asian and American ginsengs based on a UHPLC-QTOF/MS/MS metabolomics approach. Phytochem. Anal. 26: 145-160. https://doi.org/10.1002/pca.2546
- Cha, T. W., Kim, M., Kim, M., Chae, J. S. and Lee, J. H. (2016) Blood pressure-lowering effect of Korean red ginseng associated with decreased circulating Lp-PLA activity and lysophosphatidylcholines and increased dihydrobiopterin level in prehypertensive subjects. Hypertens. Res. 39: 449-456. https://doi.org/10.1038/hr.2016.7
- Stavro, P. M., Woo, M., Heim, T. F., Leiter, L. A. and Vuksan, V. (2005) North American ginseng exerts a neutral effect on blood pressure in individuals with hypertension. Hypertension 46: 406-411. https://doi.org/10.1161/01.HYP.0000173424.77483.1e
- Stavro, P. M. (2006) Long-term intake of North American ginseng has no effect on 24-hour blood pressure and renal function. Hypertension 47.
- Kwan, C. Y. (1998) Differential vascular effects of Panax ginseng and Panax quinquefolius extract. Proceedings of the 1st European Ginseng Congress, Marburg, Germany 45-53.
- Kwan, C. Y. (1999) The Yin and Yang of vascular effects of ginseng: New evidence for and old concept. Abstracts of International '99 Ginseng conference. 1999 Jul 9-11, Hong Kong 45(A29).
- Kwan, C. Y. and Kwan, T. K. (2000) Effects of Panax notoginseng saponins on vascular endothelial cells in vitro. Acta Pharmacol. Sin. 21: 1101-1105.
- Kang, M., Yoshimatsu, H., Oohara, A., Kurokawa, M., Ogawa, R. and Sakata, T. (1995) Ginsenoside Rg1 modulates ingestive behavior and thermal response induced by interleukin-1 beta in rats. Physiol. Behav. 57: 393-396. https://doi.org/10.1016/0031-9384(94)00231-S
- Sengupta, S., Toh, S. A., Sellers, L. A., Skepper, J. N., Koolwijk, P., Leung, H. W., Yeung, H. W., Wong, R. N., Sasisekharan, R. and Fan, T. P. (2004) Modulating angiogenesis: the yin and the yang in ginseng. Circulation 110: 1219-1225. https://doi.org/10.1161/01.CIR.0000140676.88412.CF
- Ahn, H. Y., Hong, S. Y., Kim, J. Y. and Kwon, O. (2013) Panax ginseng extract rich in ginsenoside protopanaxatriol offers combinatorial effects in nitric oxide production via multiple signaling pathways. Springerplus 2: 96. https://doi.org/10.1186/2193-1801-2-96
- Hong, B. N., Do, M. H., Her, Y. R., Lee, Y. R. and Kang, T. H. (2015) The effects of Panax ginseng and Panax quinquefolius on thermoregulation in animal models. Evid. Based Complement Alternat. Med.: 748041.
- Cho, H. T., Kim, J. H., Lee, J. H. and Kim, Y. J. (2017) Effects of Panax ginseng extracts prepared at different steaming times on thermogenesis in rats. Journal of Ginseng Research 41: 347-352. https://doi.org/10.1016/j.jgr.2016.07.001
- Nabata H., Sato, H. and Takagi, K. (1973) Pharmacological studies of netural saponins (GNS) of Panax ginseng root. Japan J. Pharmacol. 23: 29-41. https://doi.org/10.1254/jjp.23.29
- Yuan, W. X., Wu, X. J., Yang, F. X., Shang, X. H. and Zhang, L. L. (1989) Effects of ginseng root saponins on brain monoamines and serum corticosterone in heat-stressed mice. Zhongguo Yao Li Xue Bao 10: 492-496.
- Bhargava, H. N. and Ramarao, P. (1991) The effect of Panax ginseng on the development of tolerance to the pharmacological actions of morphine in the rat. Gen. Pharmacol. 22: 521-525. https://doi.org/10.1016/0306-3623(91)90017-Z
- Xiao, H., Tan, C., Yang, G. and Dou, D. (2017) The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism rats. J. Ginseng Res. 41: 556-565. https://doi.org/10.1016/j.jgr.2016.11.005
- Cheng, X. J., Yin. C. J., Qui J. and Zou, S. Q. (1986) Comparison of action of Panax ginsenoside and Quinoquenoside on antiwarm stress in mice. J. of Shenyang College of Pharmacy 3: 170-172.
- Hong, H. D., Kim, Y. C., Choi, S. Y., Rho, J., Lee, Y. C. and Seo, J. Y. (2006) Effects of Korean ginseng (Panax ginseng, C. A. Meyer) extracts on rat exposed to heat environment. Journal of Ginseng Research 30: 119-205.
- Kim, D. H., Lee, S. R. and Kim, S. H. (1995) Effect of body & head of Korean red ginseng and western ginseng on body temperature, pulse rate, and the hematological changes in rat treated with heat & cold stimuli. J. of Oriental Medical Pathology 10: 197-215.
- Kim, K. J., Yoon, K. Y., Hong, H. D. and Lee, B. Y. (2015) Role of the red ginseng in defense against the environmental heat stress in Sprague Dawley rats. Molecules 20: 20240-20253. https://doi.org/10.3390/molecules201119692
- Cheng, X. J., Liu, Y. L., Deng, Y. S., Lin, G. F. and Luo, X. T. (1987) Effects of ginseng root saponins on central transmitters and plasma corticosterone in cold stress mice and rats. Zhongguo Yao Li Xue Bao 8: 486-489.
- Kaneko, H. and Nakanishi, K. (2004) Proof of the mysterious efficacy of ginseng: basic and clinical trials: clinical effects of medical ginseng, korean red ginseng: specifically, its antistress action for prevention of disease. J. Pharmacol. Sci. 95: 158-162. https://doi.org/10.1254/jphs.FMJ04001X5
- Kaneko, H. (1980) Studies on clinical effects of ginseng: 2nd report; effects of ginseng at acute massive dosage on circulatory function. Proceedings of the 3rd International Ginseng Symposium, Seoul, Korea. 193-196.
- Kaneko, H. Nakanishi, K. and Murakami, A. (1984) Vasodilator action of ginsenosides. Clinic and Study (Rinsho to Kenkyu) 61: 2657-2662.
- Yoshimatsu, H., Sakata, T., Machidori, H., Fujimoto, K., Yamatodani, A. and Wada, H. (1993) Ginsenoside Rg1 prevents histaminergic modulation of rat adaptive behavior from elevation of ambient temperature. Physiol. Behav. 53: 1-4. https://doi.org/10.1016/0031-9384(93)90002-W
- Wang, J. B., Jin, C., Xiao, X. H. and Zhao, Y. L.(2008). (2008) Review and thinking of study of nature of Chinese material medica. Chin. J. Tradit. Chin. Med. 7: 572-576.
- Kuang, H. and Cheng, W. (2009) Studies on the capability of properties and flavors of Chinese Medicine to be split and combined-A new assumption on the theory of properties and flavors of Chinese Medicine and the research method. World Sci. Technol./Moderniz Trad. Chin. Med. Mater. Med. 11: 768-771.
- Huang, L., Yu, R. Y., Wang, T. M., Chen, W., Peng, S. H. and Liu, H. N. (2011) Status and prospect on studies of four properties for traditional Chinese Materia Medica. Chin. J. Exp. Tradit. Med. Formulae 17: 270-274.
- Wu, Y. F. (1981) A case report of ginseng abuse induced side effects. Chin. J. Clin. 4: 21.
- Sudar, E., Velebit, J., Gluvic, Z., Zakula, Z., Lazic, E., Vuksanovic- Topic, L., Putnikovic, B., Neskovic, A. and Isenovic, E. R. (2008) Hypothetical mechanism of sodium pump regulation by estradiol under primary hypertension. J. Theor. Biol. 251: 584-592. https://doi.org/10.1016/j.jtbi.2007.12.023
- Su, X. and Sun, D. Z. (2015) Theoretical analysis of internal heat caused by taking ginseng. China J. Tradit. Chin. Med. Pharm. 2: 494-495.
- Xu, X. and Dou, D. (2016) The ginseng's fireness is associated with the lowering activity of liver Na(+)-K(+)- ATPase. J. Ethnopharmacol. 190: 241-250. https://doi.org/10.1016/j.jep.2016.06.024
- Zhang, X. R., Zhao, Y. L., Wang, J. B., Zhou, C. P., Liu, T. S., Zhao, H. P., Ren, Y. S., Yan, D. and Xiao, X. H. (2009) Differences between cold and hot natures of processed Radix ginseng rubra and Panax quinquefolius L. based upon mice temperature tropism. Zhonghua Yi Xue Za Zhi 89: 1994-1998.
- Xu, C., Xu, D. and Qu, Z. (2005) Advances in research of the mechanism of hypothyroidism on the method of warmly invigorating kidney yang. Chin. J. Information on Trad. Chin. Med. 12: 107-108.
- Jia, X. (2007) The study on the therapeutic mechanisms of the prescription warming the kidney and invigorating the spleen on rat's experimental hypothyroidism. Tianjin: Tianjin University of Traditional Chinese Medicine.
- Choi, G. Y., Cho, J. H., Jang, J. B. and Lee K. S. (2003) A clinical study on the effect of ginseng to control superficial body temperature. Journal of Oriental Medical Thermology 2: 49-55.
- Kaneko, H. (1995) 紅蔘の 末梢循環 改善作用とその證明.藥用人蔘. '95(熊谷朗編), 共立出版. 112-113.
- Seo, J. C., Lee, K. L., Byun, J. S., Kim, M. S., Ha, I. D., Heo, Z. J. and Leem, K. H. (2003) Double-blind randomized controlled trials on superficial body temperature of Korean ginseng and American ginseng in Koreans and Chineses. Korean J. Herbology 18: 71-86.
- Seo, J. C., Han, S. W., Byun, J. S., An, H. D., Cho, G. H., Leem, K., Heo, Z. J., Yi, J. and Jin, M. (2005) The effects of ginseng and American Ginseng on general symptom in Koreans and Chineses- double-blind randomized controlled trials. J. Ginseng Res. 29: 27-36. https://doi.org/10.5142/JGR.2005.29.1.027
- Lee, J. H., Cho, J. A., Ki, C. Y., Son, Y. K., Park, J. H., Park, M. K. and Han, Y. N. (2003) The effects of ginseng on hemodynamics and body temperature in healthy young man, Proceedings of the Ginseng society Conference. The Korean Society of Ginseng 36-37.
- Seo, J. C., Lee, S. Y., Lee, K. M., Lee, S. C., Jeong, T. Y., An, H. D., Han S. W., Ha, I. D., Heo, Z. J., Lee, K. L. and Kim, M. S. (2004) double-blind randomized controlled trials on blood pressure and pulse rate of Korean Ginseng and American Ginseng in Koreans and Chineses. Korean J. Oriental Physiology & Pathology 18: 606-611.
- Choi, K. T., Choi, K. M., Sun, C., Zhou, Y., Kao, S. T., Binh, T. Q., Thuy T. H., Kwak, M. A., Kim, D. J., Byun, J. S., Hoang, V. A., Kim, Y. J., Min, J. W. and Yang, D. C (2014) The 11th International Symposium on Ginseng 429-444.
- Lee, C. R., Cho. K. H., Rhee, J. W., Na, B. J., Kim, T. H., Jung, W. S., Moon, S. K., Bae, H. S. and Kim, Y. S. (2005) The effect of Korean, Chinese and American Ginseng on blood pressure of hypertensive patients. J. Korean Oriental. Med. 26: 228-238.
- Kim, D. H., Jun, X., Zhang, L. X., Xu, Y. H., Kim, Y. C., Bang, K. H., Kim, J. U., Cha, S. W., Chang, I. B. and Li, L. (2015) Study on truth of fire-heat symptoms and adverse reation of Panax ginseng. Proceedings of the Medicinal Crop Society Conference. The Korean Society of Medicinal Crop. Science 201: 3-14.
- Lee, H. W., Lim, H. J., Jun, J. H., Choi, J. and Lee, M. S. (2017) Ginseng for treating hypertension: A systematic review and meta-analysis of double blind, randomized, placebo-controlled trials. Curr. Vasc. Pharmacol. 15: 549-556.
- Blumenthal, M., Hall, T., Rister, R. and Steinhoff, B. (1996) The German commission E Monographs. Klein, S, and Rister, R. eds, American Botanical Council, Austin, TX, U.S.A.
- World Health Organization (1999) WHO monographs on selected medicinal plants 1: 168-182.
- PPRC(Pharmacopoeia of the People' Republic of China). Vol.1: 8-9 and 131-132, Chinese medical science and technology press, 2015.
- National Toxicology Program (2011) Toxicology and carcinogenesis studies of ginseng (CAS No. 50647-08-0) in F344/N rats and B6C3F1 mice (gavage studies). Natl. Toxicol. Program Tech. Rep. Ser. 567: 1-149.
- Kim, S. H., Lee, S. R., Do, J. H., Lee, S. K. and Lee, K. S. (1995) Effects of Korean red ginseng and western ginseng on body temperature, pulse rate, clinical symptoms and the hematological changes in Human. Korean J. Ginseng Sci. 19: 1-16.