Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Prevalence of dog erythrocyte antigen (DEA) 1 among Jindo dogs

진돗개에서 개적혈구항원(dog erythrocyte antigen) 1 혈액형 조사

  • Lee, Jeong-Chi (Department of Clinical Pathology, Gwangju Health University)
  • 이정치 (광주보건대학교 임상병리과)
  • Received : 2018.12.02
  • Accepted : 2018.12.24
  • Published : 2018.12.30
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Abstract

This study was conducted to investigate the prevalence of dog erythrocyte antigen (DEA) 1 with DEA 1.1 and DEA 1.2 on 122 Jindo dogs (29 males, 93 females) from 2014 to 2015 using a monoclonal antibody card kit (blood typing card kit, Korea Animal Blood Bank Inc., South Korea). Among the tested dogs, 14.8% (18/122) were positive for the DEA 1.1 antigen and 85.2% (104/122) were positive for the DEA 1.2 antigen. The prevalence of positive types for the DEA 1.2 antigen was significantly higher than the DEA 1.1 antigen (P<0.01). The prevalence of positive types for the DEA 1.1 antigen was higher in white-haired Jindo dogs than yellow-haired dogs (P<0.05). However, there was no gender difference in the prevalence of the DEA 1.1 antigen (P=0.665). The incidence of sensitization after the first transfusion without blood group test was 12.6% and the incidence of acute hemolytic transfusion reaction after the second transfusion in the same immunized dogs was 1.6%. Therefore, the blood group test for the DEA 1 antigen should be performed for Jindo dogs to ensure safe and effective transfusion therapy and further studies remain to be conducted for other DEAs among Jindo dogs.

Keywords

Table 1. Prevalence of Dog erythrocyte antigen DEA 1.1 and DEA 1.2 by gender, color and area among Jindo dogs using blood typing card

GCOSBX_2018_v41n4_271_t0001.png 이미지

Table 2. The probability of sensitization risk after first transfusion and the probability of an acute hemolytic reaction after second transfusion without untyped blood and cross matching test among Jindo dogs

GCOSBX_2018_v41n4_271_t0002.png 이미지

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