The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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The Effect of Laser Therapy for Diabetic Ulcer : Systematic Review

당뇨병성 궤양의 레이저치료에 대한 효과 : 체계적 문헌고찰

  • Kang, Ki-Wan (Department of Internal medicine, College of Korean medicine, Woosuk University) ;
  • Kang, Ja-Yeon (Department of Internal medicine, College of Korean medicine, Woosuk University) ;
  • Jeong, Min-Jeong (Department of Pediatrics, College of Korean medicine, Woosuk University) ;
  • Kim, Hong-Jun (Department of Prescription, College of Korean medicine, Woosuk University) ;
  • Seo, Hyung-Sik (Department of Ophthalmology, Otolaryngology and Dermatology, School of Korean Medicine, Pusan National University) ;
  • Jang, In-Soo (Department of Internal medicine, College of Korean medicine, Woosuk University)
  • 강기완 (우석대학교 한의과대학 한방내과학교실) ;
  • 강자연 (우석대학교 한의과대학 한방내과학교실) ;
  • 정민정 (우석대학교 한의과대학 소아과학교실) ;
  • 김홍준 (우석대학교 한의과대학 방제학교실) ;
  • 서형식 (부산대학교 한의과대학 한방안이비인후피부과학교실) ;
  • 장인수 (우석대학교 한의과대학 한방내과학교실)
  • Received : 2017.10.16
  • Accepted : 2017.11.15
  • Published : 2017.11.25
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Abstract

Objectives : The purpose of this study is to investigate the effect of laser therapy for diabetic ulcer by using methods of systematic review. Methods : In this review, PubMed, Cochrane library, Web of Science, CNKI, CiNii, J-STAGE, NDSL and OASIS were used as the search engines. The search period is from the start date of the search engine to October 3, 2016. Randomized controlled trials(RCTs) using laser therapy for diabetic ulcer were searched and extracted by two independent researchers. Risk of bias(RoB) of Cochrane was used to assess methodological quality of studies. Results : Finally, five RCTs were selected. The follow-up period ranged from 15 days to 20 weeks. InGaAlP laser, GaAlAs laser and light emitting diode(LED) were used to treat diabetic ulcer. The clinical trials used sham laser irradiation or standard treatment as control in comparison to laser therapy. The endpoints included ulcer size, rate of healing and time to healing with follow-up period. The RCTs demonstrated therapeutic outcomes with no adverse effect. Most items of RoB were unclear and methodological quality was low. Conclusions : Our analysis suggests that laser therapy has therapeutic effects for diabetic ulcer. However, more systematic and stringent clinical trials will be required.

Keywords

References

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