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대구지역 유통 한약재의 유해금속 함량에 관한 연구

A Study on the Hazardous Metal Content of Herbal Medicines in the Daegu Area

  • 이진희 (대구광역시 보건환경연구원 약품화학과) ;
  • 김지연 (대구광역시 보건환경연구원 약품화학과) ;
  • 박상규 (대구광역시 보건환경연구원 약품화학과) ;
  • 이재호 (대구광역시 보건환경연구원 약품화학과) ;
  • 윤종호 (대구광역시 보건환경연구원 약품화학과) ;
  • 한기동 (영남대학교 생명응용과학대학 식품공학과)
  • Lee, Jin hee (Department of Pharmaceutical Chemicals, Daegu Metropolitan City Institute of Health & Environment) ;
  • Kim, Ji Yeon (Department of Pharmaceutical Chemicals, Daegu Metropolitan City Institute of Health & Environment) ;
  • Park, Sang Gyu (Department of Pharmaceutical Chemicals, Daegu Metropolitan City Institute of Health & Environment) ;
  • Lee, Jae Ho (Department of Pharmaceutical Chemicals, Daegu Metropolitan City Institute of Health & Environment) ;
  • Yoon, Jong Ho (Department of Pharmaceutical Chemicals, Daegu Metropolitan City Institute of Health & Environment) ;
  • Han, Gi Dong (Department of Food Science and Technology, College of Life Applied Science, Yeungnam University)
  • 투고 : 2017.04.25
  • 심사 : 2017.08.19
  • 발행 : 2017.08.28

초록

Objectives: The hazardous metals content of medicinal herbs distributed in the Daegu area was investigated, and the place of origin and the content of herbicides and medicinal components were studied. Methods: An analysis of hazardous metals content (10 types) was carried out on 164 samples of 99 types of herbal medicines. Among the total samples, 45 were domestic and 119 were imported. Hg was analyzed by the amalgamation method. Other hazardous metals content (nine types) was digested using the microwave method and measured by inductively coupled plasma optical emission spectrometry (ICP-OES). Results: The mean values of the hazardous metals content in the herbal medicines were Pb 1.0833 mg/kg, As 0.0136 mg/kg, Cd 0.0840 mg/kg, Cr 3.7120 mg/kg, Cu 4.2666 mg/kg, Mn 40.080 mg/kg, Ni 1.4330 mg/kg, Sb 0.1053 mg/kg, Al 202.64 mg/kg and Hg 0.0062 mg/kg. Three of the samples violated the Ministry of Food and Drug Safety (MFDS) regulatory guidance on cadmium (less than 0.3 mg/kg). The measured values of heavy metals (Pb, As, Cd, Hg) showed levels below the recommended levels for herbal medicines in MFDS regulatory guidance. In the comparison of domestic samples with imported herbal medicines, it was found that one domestic and two imported samples surpassed the maximum residue limits for cadmium. The median values of the hazardous metals detected in the three medicinal parts of the root, leaf (branch), and flower (seed and fruit) were as follows. Cr, Ni, Sb and Al were highly detected in roots, Pb, Cd, Mn, Hg in leafs (branch), and As, Cu in flowers (seed and fruit). Conclusion: There were various kinds of hazardous metals which were detected at high levels according to the place of origin of the medicinal herb and the parts the plant. For hazardous metals for which no acceptance criteria have been established, safety standards should be further studied and managed to ensure the safety of herbal medicines.

키워드

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