Journal of Yeungnam Medical Science

영남대 의대 학술지 편집위원회 (Yeungnam University College of Medicine, Yeungnam University Institute Medical Science)
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Multifocal nodular lymphoid hyperplasia of the lung

  • Lee, Gil Tae (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences) ;
  • Kim, Eun Kyoung (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences) ;
  • Cho, Eirie (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences) ;
  • Lee, Seung-Sook (Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences) ;
  • Kim, Seo Yun (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences) ;
  • Kim, Cheol Hyeon (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences) ;
  • Kim, Hye-Ryoun (Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences)
  • 투고 : 2015.07.29
  • 심사 : 2015.09.23
  • 발행 : 2017.06.30
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초록

Nodular lymphoid hyperplasia (NLH) is a benign lymphoproliferative disease that can affect the lung. Because of its rarity, little is known about the etiology and natural history of NLH. Most cases are usually asymptomatic and found incidentally on imaging studies. Imaging finding of NLH has shown most commonly as a solitary lesion, although multifocal pulmonary nodules may be seen. Surgical resection has proved curative in the cases previously described. We report a rare case of NLH in a 55 year-old man who presented with bilateral multiple pulmonary nodules on chest radiography. Open biopsy was performed from the upper and lower lobe of the left lung. The lesions were pathologically diagnosed as pulmonary NLH. Multifocal residual nodules in both lungs remain stable without spontaneous regression during the 3 years of follow-up.

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참고문헌

  1. Kradin RL, Mark EJ. Benign lymphoid disorders of the lung, with a theory regarding their development. Hum Pathol 1983; 14:857-67. https://doi.org/10.1016/S0046-8177(83)80161-0
  2. Abbondanzo SL, Rush W, Bijwaard KE, Koss MN. Nodular lymphoid hyperplasia of the lung: a clinicopathologic study of 14 cases. Am J Surg Pathol 2000;24:587-97. https://doi.org/10.1097/00000478-200004000-00015
  3. Saltzstein SL. Pulmonary malignant lymphomas and pseudolymphomas: classification, therapy, and prognosis. Cancer 1963;16:928-55. https://doi.org/10.1002/1097-0142(196307)16:7<928::AID-CNCR2820160709>3.0.CO;2-H
  4. Nicholson AG. Pulmonary lymphoproliferative disorders. Curr Diagn Pathol 2000;6:130-9. https://doi.org/10.1054/cdip.2000.0027
  5. Koss MN. Pulmonary lymphoid disorders. Semin Diagn Pathol 1995;12:158-71.
  6. Li G, Hansmann ML, Zwingers T, Lennert K. Primary lymphomas of the lung: morphological, immunohistochemical and clinical features. Histopathology 1990;16:519-31. https://doi.org/10.1111/j.1365-2559.1990.tb01157.x
  7. Guinee DG Jr. Update on nonneoplastic pulmonary lymphopro liferative disorders and related entities. Arch Pathol Lab Med 2010;134:691-701.
  8. Howling SJ, Hansell DM, Wells AU, Nicholson AG, Flint JD, Müller NL. Follicular bronchiolitis: thin-section CT and histologic findings. Radiology 1999;212:637-42. https://doi.org/10.1148/radiology.212.3.r99se04637
  9. Ryu JH, Myers JL, Swensen SJ. Bronchiolar disorders. Am J Respir Crit Care Med 2003;168:1277-92. https://doi.org/10.1164/rccm.200301-053SO