Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Antifungal Effect of Sanguisorba officinalis L. fractions on Candida albicans

지유 분획의 Candida albicans에 대한 항균효과

  • Received : 2017.06.14
  • Accepted : 2017.06.21
  • Published : 2017.06.30
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Abstract

We have studied the antifungal effect of 19 medicinal plants with paper disc diffusion method against candida albicans. As a result, Sanguisorba officinalis L., Cinnamomum cassia, Rheum coreanum, Perilla frutescens and Eugenia caryophyllata have been found to be effective against C. albicans. Among these, Sanguisorba officinalis L. was most effective at 24 hours and 48 hours. Its clear zone diameter was 17 mm for 24 hours and 16 mm for 48 hours. The antifungal activity of the solvent fraction of Sanguisorba officinalis L. by n-hexane, chloroform, ethyl acetate and n-butanol was the best for the chloroform fraction of 28 mm for 24 hours and 18 mm for 48 hours. The MIC concentration of the chloroform fraction was $80{\mu}g/50{\mu}l$ at 24 hours and $240{\mu}g/50{\mu}l$ at 48 hours.

Keywords

References

  1. Lee, M. O., Oh, H. G., Park, S. H., Lee, H. A., Song, J. and Kim, O. (2010) Antioxidant Activities of Sanguisorba officinalis and Stichopus japonicus. Laboratory Animal Res., 26: 31-36. https://doi.org/10.5625/lar.2010.26.1.31
  2. An, R. B., Tian, Y. H., Oh, H. C., and Kim, Y. C. (2005) In vitro free radical scavenging and hepatoprotective compound from Sanguisorbae radix. Nat. Prod. Sci., 11: 119-122.
  3. Cai, Z., Li, W., Wang, H., Yan, W., Zhou, Y., Wang, G. and Wang, F. (2012) Anti-tumor and immunomodulating activities of a polysaccharide from the root of Sanguisorba officinalis L. Int. J. Biol. Macromol., 51: 484-488. https://doi.org/10.1016/j.ijbiomac.2012.05.029
  4. Shin, T. Y., Lee, K. B. and Kim, S. H. (2002) Anti-allergic effects of Sanguisorba officinalis on animal models of allergic reactions. Immunopharmacol. Immunotoxicol., 24: 455-468. https://doi.org/10.1081/IPH-120014729
  5. Choi, E. S., Kim, J. S., Kwon, K. H., Kim, H. S., Cho, N. P. and Cho, S. D. (2012) Methanol extract of Sanguisorba officinalis L. with cytotoxic activity against PC3 human prostate cancer cells. Mol. Med. Reports, 6: 670-674. https://doi.org/10.3892/mmr.2012.949
  6. Kokoska, L., Polesny, Z., Rada, V., Nepovim, A. and Vanek, T. (2002) Screening of some Siberian medicinal plants for antimicrobial activity. M. Ethnopharmacol. 82: 51-53. https://doi.org/10.1016/S0378-8741(02)00143-5
  7. Wang, Z., Loo, W. T., Wang, N., Chow, L. W., Wang, D., Han, F. and Chen, J. P. (2012) Effect of Sanguisorba officinalis L. on breast cancer growth and angiogenesis. Expert opinion on therapeutic targets, 16: S79-S89. https://doi.org/10.1517/14728222.2011.642371
  8. Mayer, F. L., Wilson, D. and Hube, B. (2013) Candida albicans pathogenicity mechanisms. Virulence, 4: 119-128. https://doi.org/10.4161/viru.22913
  9. Calderone, R. A. and Fonzi, W. A. (2001) Virulence factors of Candida albicans. Trends in Microbiol., 9: 327-335. https://doi.org/10.1016/S0966-842X(01)02094-7
  10. Nobile, C. J., Schneider, H. A., Nett, J. E., Sheppard, D. C., Filler, S. G., Andes, D. R. and Mitchell, A. P. (2008) Complementary adhesin function in C. albicans biofilm formation. Current Biol., 18: 1017-1024. https://doi.org/10.1016/j.cub.2008.06.034
  11. Al-Fattani, M. A. and Douglas, L. J. (2006) Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance. J. Medical Microbiol., 55: 999-1008. https://doi.org/10.1099/jmm.0.46569-0
  12. Blanco, M. T., Blanco, J., Sanchez-Benito, R., Perez-Giraldo, C., Moran, F. J., Hurtado, C. and Gomez-Garcia, A. C. (1997) Incubation temperatures affect adherence to plastic of Candida albicans by changing the cellular surface hydrophobicity. Microbios, 89: 23-28.
  13. Carson, C. F. and Riley, T. V. (1995) Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia. J. Applied Bacteriol., 78: 264-269. https://doi.org/10.1111/j.1365-2672.1995.tb05025.x
  14. Balouiri, M., Sadiki, M. and Ibnsouda, S. K. (2016) Methods for in vitro evaluating antimicrobial activity: A review. J. Pharm. Analysis, 6: 71-79. https://doi.org/10.1016/j.jpha.2015.11.005
  15. Lee, J. J., Choi, H. S., Lee, J. H., Jung, C. J. and Lee, M. Y. (2005) The effects of ethylacetate fraction of Sanguisorba officinalis L. on experimentally-induced acute gastritis and peptic ulcers in rats. J. Kor. Society of Food Sci. Nutri., 34: 1545-1552. https://doi.org/10.3746/jkfn.2005.34.10.1545
  16. Shin, J., Kim, J. S., Kwon, K. H., Nam, J. S., Jung, J. Y., Cho, N. P. and Cho, S. D. (2012) Apoptotic effect of hot water extract of Sanguisorba officinalis L. in human oral cancer cells. Oncology Letters, 4: 489-494. https://doi.org/10.3892/ol.2012.748
  17. Zhu, X., Wang, K., Zhang, K., Huang, B., Zhang, J., Zhang, Y. and Zhou, F. (2013) Ziyuglycoside II inhibits the growth of human breast carcinoma MDA-MB-435 cells via cell cycle arrest and induction of apoptosis through the mitochondria dependent pathway. Int. J. Molecular Sci., 14: 18041-18055. https://doi.org/10.3390/ijms140918041
  18. Zhu, A. K., Zhou, H., Xia, J. Z., Jin, H. C., Wang, K., Yan, J. and Shan, T. (2013) Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/ Bcl-2 expression and activating caspase-3 pathway. Brazilian J. Med. Biol. Res., 46: 670-675. https://doi.org/10.1590/1414-431X20133050
  19. Li, W. Y., Chan, S. W., Guo, D. J. and Yu, P. H. F. (2007) Correlation between antioxidative power and anticancer activity in herbs from traditional Chinese medicine formulae with anticancer therapeutic effect. Pharm. Biol., 45: 541-546. https://doi.org/10.1080/13880200701498879
  20. Gan, R. Y., Xu, X. R., Song, F. L., Kuang, L. and Li, H. B. (2010) Antioxidant activity and total phenolic content of medicinal plants associated with prevention and treatment of cardiovascular and cerebrovascular diseases. J. Medi. Plants Res., 4: 2438-2444.
  21. Cho, J. Y., Yoo, E. S., Cha, B. C., Park, H. J., Rhee, M. H. and Han, Y. N. (2006) The inhibitory effect of triterpenoid glycosides originating from Sanguisorba officinalis on tissue factor activity and the production of TNF-${\alpha}$. Planta Medica, 72: 1279-1284. https://doi.org/10.1055/s-2006-947257
  22. Kim, S. R., Won, J. H. and Kim, M. R. (2011) Antimicrobial Activity against Food Hazardous Microorganisms and Antimutagenicity against Salmonella serotype Typhimurium TA100 of an Ethanol Extract from Sanguisorba officinalis L. Kor. J. Food Cookery Sci., 27: 17-26. https://doi.org/10.9724/kfcs.2011.27.4.017
  23. Janovska, D., Kubikova, K. and Kokoska, L. (2003) Screening for antimicrobial activity of some medicinal plants species of traditional Chinese medicine. Czech J. Food Sci., 21: 107-110.
  24. Chin, H. S., Pack, K. J., Pack, S. H. and Kim, J. K. (2009) The effects of herbal extract mixture on anti-obesity. J. Kor. Soci. Food Sci. Nutri., 38: 32-38. https://doi.org/10.3746/jkfn.2009.38.1.032
  25. Cha, J. Y., Ha, S. E., Sim, S. M., Park, J. K., Chung, Y. O., Kim, H. J. and Park, N. B. (2008) Antimicrobial effects of ethanol extracts of Korea endemic herb plants. J. Life Sci., 18: 228-233. https://doi.org/10.5352/JLS.2008.18.2.228
  26. Shishodia, S., Majumdar, S., Banerjee, S. and Aggarwal, B. B. (2003). Ursolic acid inhibits nuclear factor-${\kappa}B$ activation induced by carcinogenic agents through suppression of I${\kappa}B$${\alpha}$ kinase and p65 phosphorylation. Cancer Res., 63: 4375-4383.
  27. Yuan, C. L., Li, Z. X. and Yang, P. Y. (2002) Extraction of Ursolic Acid from Sanguisorba officinalis L. Chine. J. Pharm., 33: 478-479.
  28. Pathak, A. K., Bhutani, M., Nair, A. S., Ahn, K. S., Chakraborty, A., Kadara, H. and Aggarwal, B. B. (2007) Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells. Mole. Cancer Res., 5: 943-955. https://doi.org/10.1158/1541-7786.MCR-06-0348
  29. Nguyen, M. H., Peacock, J. E., Morris, A. J., Tanner, D. C., Nguyen, M. L., Snydman, D. R. and Victor, L. Y. (1996) The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. American J. Medi., 100: 617-623. https://doi.org/10.1016/S0002-9343(95)00010-0
  30. White, T. C. (1997) Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrobial. Agents Chem., 41: 1482-1487.