Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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A Fatal Case of Colchicine Poisoning

콜히친(Colchicine) 음독 후 사망한 환자 1례

  • Ko, Seung Hyun (Department of Emergency Medicine, Catholic University of Daegu School of Medicine) ;
  • Lee, Gun Woo (Department of Emergency Medicine, Catholic University of Daegu School of Medicine)
  • 고승현 (대구가톨릭대학교 의과대학 응급의학교실) ;
  • 이건우 (대구가톨릭대학교 의과대학 응급의학교실)
  • Received : 2017.06.07
  • Accepted : 2017.06.22
  • Published : 2017.06.30
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Abstract

Colchicine is a drug that has long been used to treat a variety of illnesses; however, it reportedly has adverse effects at apparent toxic doses as well as at lower and therapeutically recommended doses. The typical therapeutic dose of colchicine is up to 2.4 mg daily, although it is sometimes as high as 8-10 mg daily. Here, we describe a case in which the patient showed sudden deterioration and died because of unintentional colchicine poisoning with a relatively small dose. When a colchicine poisoned patient visits the hospital, the physician should identify the patient's colchicine poisoning dose and concomitant drugs. Moreover, the patients should be monitored intensively for 24 to 72 hours and managed with various supportive treatment methods early and actively.

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References

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