Investigative Magnetic Resonance Imaging

Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회)
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Functional Magnetic Resonance Imaging with Arterial Spin Labeling: Techniques and Potential Clinical and Research Applications

  • Kim, Ju Ho (Department of Radiology, Gyeongsang National University Hospital) ;
  • Choi, Dae Seob (Department of Radiology, Gyeongsang National University Hospital) ;
  • Park, Sung Eun (Department of Radiology, Gyeongsang National University Hospital) ;
  • Choi, Ho Cheol (Department of Radiology, Gyeongsang National University Hospital) ;
  • Kim, Seong Hu (Department of Radiology, Masan University)
  • Received : 2017.02.13
  • Accepted : 2017.04.17
  • Published : 2017.06.30
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Abstract

Purpose: To describe technical methods for functional magnetic resonance imaging (fMRI) study with arterial spin labeling (ASL) compared to blood oxygenation level-dependent (BOLD) technique and discuss the potential of ASL for research and clinical practice. Materials and Methods: Task-based (n = 1) and resting-state fMRI (rs-fMRI) (n = 20) were performed using ASL and BOLD techniques. Results of both techniques were compared. Results: For task-based fMRI with finger-tapping, the primary motor cortex of the contralateral frontal lobe and the ipsilateral cerebellum were activated by both BOLD and ASL fMRI. For rs-fMRI of sensorimotor network, functional connectivity showed similar results between BOLD and ASL. Conclusion: ASL technique has potential application in clinical and research fields because all brain perfusion imaging, CBF measurement, and rs-fMRI study can be performed in a single acquisition.

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References

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