Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Resistance to fluoroquinolone of Staphylococcus pseudintermedius isolated from dogs and cats in Daegu

대구지역 개와 고양이에서 분리된 Staphylococcus pseudintermedius의 fluoroquinolone 내성

  • Cho, Jae-Keun (Kyung-Metropolitan Health & Enviornmental Research Institute) ;
  • Kim, Jeong-MI (Kyung-Metropolitan Health & Enviornmental Research Institute) ;
  • Kim, Hwan-Deuk (Kyung-Metropolitan Health & Enviornmental Research Institute) ;
  • Kim, Kyung-Hee (Kyung-Metropolitan Health & Enviornmental Research Institute) ;
  • Yang, Chang-Ryoul (Kyung-Metropolitan Health & Enviornmental Research Institute)
  • 조재근 (대구광역시보건환경연구원) ;
  • 김정미 (대구광역시보건환경연구원) ;
  • 김환득 (대구광역시보건환경연구원) ;
  • 김경희 (대구광역시보건환경연구원) ;
  • 양창렬 (대구광역시보건환경연구원)
  • Received : 2017.03.02
  • Accepted : 2017.03.21
  • Published : 2017.03.30
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Abstract

The purpose of this study was to investigated the fluoroquinolone (FQ) resistance and presence of gyrA and grlA gene in 87 Staphylococcus pseudintermedius isolates obtained from clinical samples of dogs and cats. Also, the profiles of FQ resistance compared with methicillin resistant S. pseudintermedius (MRSP) isolates. FQ resistance was observed for enrofloxacin (41.4%), ciprofloxacin (39.1%), norfloxacin (36.8%), ofloxacin and levofloxacin (32.2%, respectively), and moxifloxacin (31.0%). Thirty-eight (43.7%) of 87 S. pseudintermedius isolates were resistant to more than one FQ. Twenty-six (64.5%) of 38 FQ resistant isolates were resistant to all the six FQ tested. Of 38 FQ resistant isolates, gyrA gene was detected in all isolates but grlA gene was not found. Moreover, 19 MRSP isolates were resistant to enrofloxacin (63.2%), ciprofloxacin (57.9%), norfloxacin (52.6%), and ofloxacin, levofloxacin and moxifloxacin (47.4%, respectively). FQ resistance were highly prevalence in S. pseudintermedius isolates from dogs and cats. Our results emphasize the prudent use of antimicrobial agents to companion animals is necessary for prevent antimicrobial resistance.

Keywords

References

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