DOI QR코드

DOI QR Code

비대성 흉터를 최소화하는 생체적합성 재료설계와 미니돼지에 대한 치료 효과

Biocompatible Material Design Minimizing Hypertrophic Injury and Treatment Effects using a Mini-pig

  • 투고 : 2017.11.18
  • 심사 : 2017.11.26
  • 발행 : 2017.12.31

초록

Recently, biomedical-grade texture material gauze has often been used to treat wounds. At this time, it is difficult to remove scratches and pushed gauze; if you remove it with force, the tissue may separate and bleeding may occur again. In this study, we studied a method to apply medical-grade silicone material. Similar to the research result that hypertrophic wounds reduce the thickness of scar marks. Through mini-pig experiments, we evaluated the effects on scar treatment. The test results showed that the silicone cover layer applied to the wound site had a sealing effect on the wound area, skin temperature, and histopathological examination. In conclusion, gel treatment utilizing a biocompatible substance had the effect of minimizing hypertrophic scars.

키워드

참고문헌

  1. Kim, D. K., "Structure and Characteristic of Chitosan/Bombyx mori Silk Fibroin Blend Filems," Polymer Korea, Vol. 29, No. 4, pp. 408-412, 2007.
  2. Lee, M. H. and Lee, D. H., "Biological Safety Evaluation of Polyketones as Biomaterials," Polymer, Vol. 40, No. 2, 2016.
  3. Wang, K. A., Wu, G. S., Sun, Y. and Xia, Z. F., "Advances in the research of prevention and treatment of postburn contractures of hand," Chinese journal of burns, Vol. 33, No. 1, pp. 58-61, 2017.
  4. Phan, H. and Harger, B., "Case Report: Pediatric Scar Management After Open-heart Surgery," International journal of pharmaceutical compounding, Vol. 20, No. 4, pp. 277-280, 2016.
  5. Kant, S. B. and Ferdinandus, P. I., "A new treatment for reliable functional and esthetic outcome after local facial flap reconstruction: a transparent polycarbonate facial mask with silicone sheeting," European Journal of Plastic Surgery, Vol. 40, No. 5, pp. 407-416, 2017. https://doi.org/10.1007/s00238-017-1306-y
  6. Gold, M. H. and Andriessen, A., "Hypochlorous acid gel technology-Its impact on postprocedure treatment and scar prevention," Journal of Cosmetic Dermatology, Vol. 16, No. 2, pp. 162-167, 2017. https://doi.org/10.1111/jocd.12330
  7. Fang, Q. Q. and Chen, C. Y., "The effectiveness of topical anti-scarring agents and a novel combined process on cutaneous scar management," Current Pharmaceutical Design, Vol. 23, No. 15, pp. 2268-2275, 2017.
  8. Park, D. H. and Park, S. U., "Usefullness of Mask Pack Sheets Including Marine Materials: Skin Regeneration Effect," Journal of Fish Aquat Sci, Vol. 45, No. 2, pp. 167-172, 2012.
  9. Kang, H. G. and Lee, S. K., "Hematological Evaluation for Quality Control of Minipig as a Non-rodent Laboratory Animal," Jorunal of Biomedical Research, Vol. 11, No. 1, pp. 19-26, 2010.
  10. Kim, O. H., "Development of a Magnetic Seal and the Leak Test," Journal of the Korean Society of Manufacturing Process Engineers, Vol. 10, No. 2, pp. 79-83, 2011.
  11. Kim, S. Y. and Han, M. S., "The Inspection of Press Forming Product at Automobile through Application of Reverse Engineering System," Journal of the Korean Society of Manufacturing Process Engineers, Vol. 4, No. 2, pp. 179-183, 2005.
  12. Hwang, P. J. and Kwak, J. H., "Clinical Features of Acute Noroviral Gastroenteritis in Children : Comparison with Rotaviral Gastroenteritis," Journal of PEDIATRICSE, Vol. 52, No. 4, pp. 453-457, 2009.