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Evaluated Absorbed Dose According to Prescribed Dose and Therapeutic Technique in Radiation Therapy

방사선치료 시 처방선량과 치료기법에 따른 흡수선량 평가

  • Lee, Deuk-hee (Department of Radiation Oncology, Busan Paik Hospital, Inje University) ;
  • Park, Eun-tae (Department of Radiation Oncology, Busan Paik Hospital, Inje University) ;
  • Kim, Jung-hoon (Department of Radiological Science, College of Health Sciences, Catholic University of Pusan) ;
  • Im, In-chul (Department of Radiological Science, Dongeui University)
  • 이득희 (인제대학교 부산백병원 방사선종양학과) ;
  • 박은태 (인제대학교 부산백병원 방사선종양학과) ;
  • 김정훈 (부산가톨릭대학교 방사선학과) ;
  • 임인철 (동의대학교 방사선학과)
  • Received : 2016.09.13
  • Accepted : 2016.10.30
  • Published : 2016.10.31

Abstract

In this study, evaluated absorbed dose of moving target using PLD according to prescribed dose and therapeutic technique. First, result of MCNPX when target was deviated from exposure field was reduced dose in proportion to distance. According to prescribed dose, absorbed dose of 3D CRT was better than IMRT in low dose and IMRT was more better in high dose. Absorbed dose of 3D CRT was highest according to therapeutic technique. Therefore, 3D CRT was technique of irradiated highest dose to moving target. But, considered protective effect of normal tissue and patient condition that therapeutic technique was selected to maximized treatment efficiency.

본 논문에서는 움직이는 타깃을 대상으로 처방선량과 치료기법에 따른 흡수선량을 유리선량계를 이용하여 평가하였다. 타깃의 움직임에 따라 조사야에서 벗어나는 정도에 따른 선량을 MCNPX를 이용하여 모의모사하였으며 그 결과 조사야에서 이격하는 거리에 비례하여 감소하는 것으로 나타났다. 처방선량에 따른 흡수선량의 결과는 3D CRT의 경우 저선량에서 IMRT보다 흡수선량이 높은 것으로 나타났으며, 대선량에서는 IMRT가 더 높은 비율을 보였다. 치료기법에 따른 결과는 3D CRT가 가장 우수한 것으로 나타났으며, IMRT의 sliding window방식이 가장 낮은 것으로 나타났다. 본 연구를 통하여 3D CRT가 움직이는 타깃에 가장 높은 선량을 조사할 수 있는 기법으로 평가되었다. 하지만 정상조직의 보호효과와 환자의 상태 등을 고려한 적절한 치료기법의 선택으로 치료효과를 높일 수 있는 노력이 필요할 것이다.

Keywords

References

  1. National Cancer Information Center(www.cancer.go.kr), 2015
  2. J. S. Lee, J. N. Kim, “Efficient Data Acquisition Technique for Clinical Application of Multileaf Collimator,” Jounal of The Korea Contents Association, Vol. 8, No. 11, pp. 182-188, 2008.
  3. B. S. Park, J. H. Ahn, D. Y. Kwon, J. M. Seo, K. W. Song, “The Effect of Photoneutron Dose in High Energy Radiotherapy,” The journal of the korean society for radiotherapeutic technology, Vol. 25, No. 1, pp. 9-14, 2013.
  4. G. Budgell, "Intensity modulated radiotherapy(IMRT) and introduction," Radiography, Vol. 8, No. 4, pp. 241-249, 2000 https://doi.org/10.1053/radi.2002.0390
  5. S. H. Benediet, R. M. Cardinale, Q. Wu. R. D. Zwicker, W. C. Broaddus, R. Mohan, “Intensity-modulated stereotatic radiosurgery using dynamic micro-multileaf collimation,” Int. J Radiat Oncol Biol Phys, Vol. 50, No. 3, pp. 751-758, 2001. https://doi.org/10.1016/S0360-3016(01)01487-0
  6. E. T. Park, D. H. Lee, S. S. Kang, “Evaluation of Photoneutron by Hypofractionated Radiotherapy,” The Journal of the Korea Contents Association, Vol. 15, No. 12, pp. 347-354, 2015.
  7. ICRU. Prescribing, recording and reporting photon beam therapy(supplement to ICRU report 50), report 62, 1999. Bethesda. USA
  8. P.J. Keall, G. S. Mageras, J. M. Balter, R. S. Emery, K. Forster, S. B. Jiang, J. M. Kapatoes, D. A. Low, M. J. Murphy, B. R. Murray, C. R. Ramsey, M. B. Van Herk, S. Sastry Vedam, J. W. Wong, E. Yorke, "The management of respiratory motion in radiation oncology report of AAPM Task Group 76," The International Jounal of Medical Physics and Practice, Vo. 33, No. 10, pp. 3874-3900, 2006.
  9. F. Li, J. Li, Y. Zhang, X. Min, D. Shang, T. Fan, T. Liu, Q. Shao, "Geometrical differences in gross target volumes between 3DCT and 4DCT imaging in radiotherapy for non-small-cell lung cancer," Jounal of Radiation Research, Vo. 54, No. 5, pp. 950-956, 2013. https://doi.org/10.1093/jrr/rrt017
  10. B. G. Choi, C. H. Choi, I. G. Yun, J. S. Yang, D. M. Lee, J. M. Park, “A study to 3D dose measurement and evaluation for Respiratory Motion in Lung Cancer Stereotactic Body Radiaotherapy Treatment,” Jounal of The Korea Contents Association, Vol. 26, No. 1, pp. 59-67, 2014.
  11. J. S. Kim, E. H. Shin, J. S. Shin, S. G. Ju, Y, Y, Han, H. C. park, D. H. Choi, “The Clinical Implementation of 2D Dose Distribution QA System for the Patient Specific Respiratory-gated Radiotherapy,” Korean Journal of Medical Physics, Vol. 21, No. 2, pp. 127-136, 2010.
  12. K. M. Langen, D. T. Jones, “Organ motion and its management,” International Jounal of Radiation Oncology.Biology.Physics, Vol. 50, No. 1, pp. 265-78, 2001. https://doi.org/10.1016/S0360-3016(01)01453-5
  13. S. S. Kang, I. H. Go, G. J. Kim, S. H. Kim, Y. S. Kim, Radiation Therapeutics, 3rd edition, Cheong-gumunhwasa, Seolu, 2014.
  14. G. J. Kutcher, L. Coia, M. Gillin, W. F. Hanson, S. Leibel, R. J. Morton, J. R. Palta, J. A. Purdy, L. E. Reinstein, G. K. Svensson, M. Weller, L. Wingfield, “Comprehensive QA for radiation oncology: Report of AAPM Radiation Therapy Committee Task Group 40,” Medical Physics, Vol. 21, No. 4, pp. 581-618, 1994. https://doi.org/10.1118/1.597316
  15. R. D. Timmerman, “An overview of hypofractionatio n and introduction to this issue of seminars in radiation oncology,” Seminars in Radiation Oncology, Vol. 18, No. 4, pp. 215-222, 2008. https://doi.org/10.1016/j.semradonc.2008.04.001
  16. B. R. Lee, S. Y. Lee, M. G. Yoon, “Dosimetrci Comparison of Radiation Treatment Techniques for Breast Cancer: 3D-CRT, IMRT and VMAT,” Journal of Radiological Science and Technology, Vol. 36, No. 3, pp. 237-244, 2013.
  17. H. S. Jeon, J. H. Nam, D. Park, Y. H. Kim, W. T. Kim, D. W. Kim, Y. K. Ki, D. H. Kim, J. H. Lee, "Reading Deviations of Glass Rod Dosimeters Using Different Pre-processing Methods for Radiotherapeutic in-vivo Dosimetry," Progress in Medical Physics, Vol. 24. No. 2, pp. 92-98, 2013. https://doi.org/10.14316/pmp.2013.24.2.92
  18. T. D. L. F. Herman, E. Schnell, J. Young, H. Kim, O. Algan, E. Syzek, T. Herman, S. Ahmad, “Dosimetric comparison between IMRT delivery modes: Stepand-shoot, sliding window, and volumetric modulated arc therapy-for whole pelvis radiation therapy of intermediate-to-high risk prostate adenocarcinoma,” Jounal of Medical Physics, Vol. 38, No. 4, pp. 165-17 2, 2013. https://doi.org/10.4103/0971-6203.121193
  19. S. S. Jang, G. J. Huh, S. Y. Park, P. S. Yang, E. Y. Cho, "The impact of respiratory gating on lung dosimetry in stereotactic body radiotherapy for lung cancer," European Jounal of Medical physics, Vol. 30, pp. 682-689, 2014.

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