Journal of Preventive Medicine and Public Health

  • 제49권5호
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  • Pages.329-341
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  • 2016
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  • 1975-8375(pISSN)
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  • 2233-4521(eISSN)
대한예방의학회 (The Korean Society for Preventive Medicine)
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Short-term Effects of Ambient Air Pollution on Emergency Department Visits for Asthma: An Assessment of Effect Modification by Prior Allergic Disease History

  • Noh, Juhwan (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Sohn, Jungwoo (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Cho, Jaelim (Department of Occupational and Environmental Medicine, Gachon University Gil Hospital) ;
  • Cho, Seong-Kyung (Department of Medical Informatics and Biostatistics, Yonsei University College of Medicine) ;
  • Choi, Yoon Jung (Health Insurance Review and Assessment Service) ;
  • Kim, Changsoo (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Shin, Dong Chun (Department of Preventive Medicine, Yonsei University College of Medicine)
  • 투고 : 2016.04.09
  • 심사 : 2016.09.08
  • 발행 : 2016.09.30
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초록

Objectives: The goal of this study was to investigate the short-term effect of ambient air pollution on emergency department (ED) visits in Seoul for asthma according to patients' prior history of allergic diseases. Methods: Data on ED visits from 2005 to 2009 were obtained from the Health Insurance Review and Assessment Service. To evaluate the risk of ED visits for asthma related to ambient air pollutants (carbon monoxide [CO], nitrogen dioxide [$NO_2$], ozone [$O_3$], sulfur dioxide [$SO_2$], and particulate matter with an aerodynamic diameter <$10{\mu}m$ [$PM_{10}$]), a generalized additive model with a Poisson distribution was used; a single-lag model and a cumulative-effect model (average concentration over the previous 1-7 days) were also explored. The percent increase and 95% confidence interval (CI) were calculated for each interquartile range (IQR) increment in the concentration of each air pollutant. Subgroup analyses were done by age, gender, the presence of allergic disease, and season. Results: A total of 33 751 asthma attack cases were observed during the study period. The strongest association was a 9.6% increase (95% CI, 6.9% to 12.3%) in the risk of ED visits for asthma per IQR increase in $O_3$ concentration. IQR changes in $NO_2$ and $PM_{10}$ concentrations were also significantly associated with ED visits in the cumulative lag 7 model. Among patients with a prior history of allergic rhinitis or atopic dermatitis, the risk of ED visits for asthma per IQR increase in $PM_{10}$ concentration was higher (3.9%; 95% CI, 1.2% to 6.7%) than in patients with no such history. Conclusions: Ambient air pollutants were positively associated with ED visits for asthma, especially among subjects with a prior history of allergic rhinitis or atopic dermatitis.

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참고문헌

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