Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Incidence and Characteristics of Frey's Syndrome after Parotidectomy by Minor's Starch-Iodine Test

이하선 절제술 후 요오드-녹말 검사를 이용한 Frey 증후군의 발생 빈도 및 임상 양상

  • Kang, Tae Wook (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Song, Chang Myeon (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Kim, Hong Dae (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Ko, Seok Hwa (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Jang, Youn Il (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Ji, Yong Bae (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Tae, Kyung (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine)
  • 강태욱 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 송창면 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 김홍대 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 고석화 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 장연일 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 지용배 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 태경 (한양대학교 의과대학 이비인후-두경부외과학교실)
  • Received : 2016.03.29
  • Accepted : 2016.04.25
  • Published : 2016.05.30
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Abstract

Objectives: Frey's syndrome is an infrequent complication after parotidectomy and its incidence varies from 23.5% to 50.8% in the literature. The objective of this study was to evaluate the actual incidence and clinical characteristics of Frey's syndrome. Methods: We analyzed 31 patients who underwent parotidectomy and serial Minor's starch-iodine test. The mean follow-up period was $66{\pm}26.1$ months (range, 24-118 months). The Frey's syndrome was analyzed using a questionnaire for the assessment of the subjective symptom and Minor's starch-iodine test for the objective measurement at 1, 3, 6, and 12 months after the surgery and then every 6 or 12 months. Minor's starch-iodine test was graded from 0 to 3 according to the area of discolorization. Results: Frey's syndrome occurred in 11 patients (35.5%) on the Minor's starch-iodine test. The mean onset of Frey's syndrome on the starch-iodine test was $13.6{\pm}10.4$ months after parotidectomy. Sixteen patients (51.6%) complained about gustatory sweating and flushing. The onset of the subjective symptom was $11.27{\pm}6.96$ months after the surgery. There was a significant correlation between the grade of the starch-iodine test and the severity of subjective symptoms (P <0.001). Various factors including size and location of tumor, incision method, and extent of parotidectomy did not correlate with the Frey's syndrome. Conclusion: The incidence of Frey's syndrome was 35.5% on the Starch-Iodine test, and the onset was about postoperative 13.6 months.

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References

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