Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Adult Intracranial Gliofibroma : A Case Report and Review of the Literature

  • Kang, Ho (Department of Neurosurgery, Seoul National University Hospital) ;
  • Kim, Jin Wook (Department of Neurosurgery, Seoul National University Hospital) ;
  • Se, Young-Bem (Department of Neurosurgery, Seoul National University Hospital) ;
  • Park, Sung-Hye (Department of Pathology, Seoul National University Hospital)
  • Received : 2015.03.11
  • Accepted : 2015.08.21
  • Published : 2016.05.01
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Abstract

Gliofibroma is an extremely rare biphasic tumor with an astrocytic and benign mesenchymal component, which commonly occurs within the first two decades of life. The exact biological behavior of the tumor is not fully understood. Therefore, it is not listed as a distinct entity in the current World Health Organization classification of central nervous system tumors. Here, we describe a rare case of gliofibroma, which was located on the medial temporal lobe in a 61-year-old woman. Preoperatively, we misdiagnosed it as a meningioma because it was a well-demarcated and well-enhanced extra-axial mass with calcification and bony destruction. On the histopathological and immunohistochemical examination, the tumor consisted of a mixture of glial tissue and mesenchymal tissue and it was finally diagnosed as a gliofibroma. To our knowledge, this case of intracranial gliofibroma is in the oldest patient ever reported.

Keywords

References

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