Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)

Korean Academy of Pediatric Dentistry (대한소아치과학회)
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Irritation Fibroma Associated with Ectopic Eruption of the Maxillary Incisor

상악 중절치의 이소맹출로 인해 발생한 자극성 섬유종

  • Jeong, Younwook (Department of Pediatric Dentistry, College of Dentistry, Yonsei University) ;
  • Kang, Chungmin (Department of Pediatric Dentistry, College of Dentistry, Yonsei University) ;
  • Kim, Seunghye (Division of Pediatric Dentistry, Department of Dentistry, Ajou University School of Medicine) ;
  • Lee, Jaeho (Department of Pediatric Dentistry, College of Dentistry, Yonsei University)
  • 정연욱 (연세대학교 치과대학 소아치과학교실) ;
  • 강정민 (연세대학교 치과대학 소아치과학교실) ;
  • 김승혜 (아주대학교병원 치과학교실 소아치과) ;
  • 이제호 (연세대학교 치과대학 소아치과학교실)
  • Received : 2015.05.14
  • Accepted : 2015.06.23
  • Published : 2016.05.31
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Abstract

Irritation fibroma is a common hyperplastic lesion of the oral mucosa that can occur in response to chronic irritation or trauma. This report presents an unusual case of irritation fibroma associated with ectopic eruption of the maxillary left central incisor in a patient with Angelman syndrome. Considering the patient's medical history and cooperative ability, excisional biopsy under intramuscular sedation using midazolam was performed. The patient exhibited successful healing without lesion recurrence. It is important to perform histopathological examination followed by excisional biopsy, because other benign or malignant tumors may mimic the clinical appearance of an irritation fibroma.

자극성 섬유종은 만성적인 자극 또는 외상에 의해 발생하는 구강 내의 흔한 섬유증식성 병소이다. 자극성 섬유종과 유사한 형태의 다른 양성 또는 악성 연조직종양의 감별진단을 위해서는 병리조직학적 검사가 필요하다. 본 증례는 엔젤만 증후군 환아에서 상악 좌측 중절치의 이소맹출로 인해 자극성 섬유종이 발생하여 미다졸람을 이용한 근육내 진정 하에 절제생검을 시행한 뒤, 병소의 재발 없이 양호한 치유 결과를 나타내고 있기에 보고하는 바이다.

Keywords

References

  1. Neville BW, Damm DD, Bouquot JE, et al. : Oral and maxillofacial pathology, 3rd ed., Saunders, 507-552, 2009.
  2. Sapp JP, Eversole LR, Wysocki GP : Contemporary oral and maxillofacial pathology, 2nd ed., Mosby, 164-206, 1997.
  3. Gross GE, Pfister H, Mittermayer C : Papilloma virus particles in a fibroma of the tongue. Acta Derm Venereol, 60:315-8, 1980.
  4. Marx RE, Stern D : Oral and maxillofacial pathology: a rationale for diagnosis and treatment, 2nd ed., Quintessence Publishing Co, Inc., 399-466, 2012.
  5. Korean academy of orofacial pain and oral medicine (Ed.) : Oral medicine Vol. III, Shinhung International, Inc., 121-9, 2010.
  6. Pembrey M, Fennell SJ, Super M, et al. : The association of Angelman’s syndrome with deletions within 15q11-13. J Med Genet, 26:73-7, 1989.
  7. Williams CA, Beaudet AL, Wagstaff J, et al. : Angelman syndrome 2005: updated consensus for diagnostic criteria. Am J Med Genet A, 140:413-8, 2006.
  8. Marshall RI, Bartold PM : A clinical review of drug-induced gingival overgrowths. Aust Dent J, 44:219-32, 1999. https://doi.org/10.1111/j.1834-7819.1999.tb00224.x
  9. Thompson AL, Herman WW, Konzelman J, Collins MA : Treating patients with drug-induced gingival overgrowth. J Dent Hyg, 78:1-13, 2004.
  10. Prasad VN, Chawla HS, Singhi P, et al. : Folic acid and phenytoin induced gingival overgrowth-is there a preventive effect. J Indian Soc Pedod Prev Dent, 22:82-91, 2004.
  11. Murakami C, Nahas Pires Correa MS, Nahas Pires Correa JP, et al. : Dental treatment of children with Angelman syndrome: a case report. Spec Care Dentist, 28:8-11, 2008. https://doi.org/10.1111/j.1754-4505.2008.00003.x
  12. Kim BS, Yeo JS, Kim SO : Anesthesia of a dental patient with Angelman syndrome-A case report-. Korean J Anesthesiol, 58:207-10, 2010. https://doi.org/10.4097/kjae.2010.58.2.207
  13. Bernick S : Growths of the gingiva and palate; chronic inflammatory lesions. Oral Surg Oral Med Oral Pathol, 1:1029-41, 1948. https://doi.org/10.1016/0030-4220(48)90221-7
  14. Maryam S, Mohammadtaghi H, Soodabeh B : Localized lesions of oral cavity: a clinicopathological study of 107 cases. Research journal of medical sciences, 5:67-72, 2011. https://doi.org/10.3923/rjmsci.2011.67.72
  15. Bouquot JE, Gundlach KK : Oral exophytic lesions in 23,616 white Americans over 35 years of age. Oral Surg Oral Med Oral Pathol, 62:284-91, 1986. https://doi.org/10.1016/0030-4220(86)90010-1
  16. Buchner A, Calderon S, Ramon Y : Localized hyperplastic lesions of the gingiva: a clinicopathological study of 302 lesions. J Periodontol, 48:101-4, 1977. https://doi.org/10.1902/jop.1977.48.2.101
  17. Ntomouchtsis A, Karakinaris G, Antoniades K, et al. : Benign lip lesions. A 10-year retrospective study. Oral Maxillofac Surg, 14:115-8, 2010. https://doi.org/10.1007/s10006-009-0196-y
  18. Christopoulos P, Sklavounou A, Patrikiou A : True fibroma of the oral mucosa: a case report. Int J Oral Maxillofac Surg, 23:98-9, 1994. https://doi.org/10.1016/S0901-5027(05)80601-0
  19. Rotaru H, Choi JY, Kim SG, et al. : Transforming growth factor-alpha and oral fibroma: immunohistochemical and in situ hybridization study. J Oral Maxillofac Surg, 61:1449-54, 2003. https://doi.org/10.1016/j.joms.2003.02.001
  20. Ryu MH, Kim BI, Kim J, et al. : Expression of TGF-${\beta}1$, MMP-1 and TIMP-1 in irritation fibroma. Kor J Oral Maxillofac Pathol, 33:61-8, 2009.
  21. Dayan D, Bodner L, Wolman M, et al. : Histochemical characterization of collagen fibers in fibrous overgrowth (irritation fibroma) of the oral mucosa: effect of age and duration of lesion. Arch Gerontol Geriatr, 18:53-7, 1994. https://doi.org/10.1016/0167-4943(94)90047-7
  22. Mandel L, Baurmash H : Irritation fibroma. Report of a case. NY State Dent J, 36:344-7, 1970.
  23. Toida M, Murakami T, Tatematsu N, et al. : Irritation fibroma of the oral mucosa: a clinicopathological study of 129 lesions in 124 cases. Oral Medicine and Pathology, 6:91-4, 2001. https://doi.org/10.3353/omp.6.91