Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Study on the Effects of the Extracts from Sophora Japonica L. Flowers, Fruits and Branches on Improvements in Skin Condition

회화나무 꽃, 열매, 가지 추출물의 피부개선 효과에 관한 연구

  • Song, Hang Sun (Department of Oriental Medical and Herbal Cosmetic Sciences, Semyung University) ;
  • Jang, Hye In (Department of Oriental Medical and Herbal Cosmetic Sciences, Semyung University)
  • 송행선 (세명대학교 한방화장품과학과) ;
  • 장혜인 (세명대학교 한방화장품과학과)
  • Received : 2016.09.16
  • Accepted : 2016.11.10
  • Published : 2016.12.30
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Abstract

The purpose of this research was to examine the effect of the ehanol extracts of Sophora japonica L. (S. japonica). flowers, fruits and branches on skin enhancement with assessing anti-oxidative, whitening, and wrinkle enhancement effects. Results showed that l,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging activities were $17.68{\pm}1.59{\sim}51.40{\pm}1.04$, $27.48{\pm}0.22{\sim}50.89{\pm}0.13$ and $30.79{\pm}0.55{\sim}45.17{\pm}0.83%$, respectively, in 50~1,000 mg/L of concentrations. The capacities of inhibiting tyrosinase of ethanol extracts from S. japonica. flowers, fruits and branches were $0.27{\pm}0.12{\sim}11.38{\pm}0.57$, $0.27{\pm}0.02{\sim}0.82{\pm}0.27$ and $0.09{\pm}0.16{\sim}0.55{\pm}0.27%$, respectively. The capacities of preventing porcine pancreatic elastase (PPE) were $3.70{\pm}1.23{\sim}7.28{\pm}1.01$, $3.06{\pm}2.13{\sim}13.03{\pm}2.99$ and $6.00{\pm}0.96{\sim}9.71{\pm}0.44%$, respectively, in the case of 50~1,000 mg/L of concentrations. It is concluded that the effects of S. japonica. flowers, fruits and branches on skin improvement are varied significantly.

본 연구에서는 Sophora japonica L. (S. japonica)학명의 콩과 식물 낙엽교목인 회화나무의 꽃, 열매, 가지 에탄올 추출물의 총 폴리페놀 함량 및 l,1-diphenyl-2-picryl-hydrazyl (DPPH) 라디칼 소거능 측정, 티로시나제 활성 저해력 측정 및 porcine pancreatic elastase (PPE) 저해력 측정을 통하여 기능성 화장품 소재로서의 활용 가능성을 확인하였다. 그 결과 총 폴리페놀 함량은 평균 각각 261.37 mg/g, 187.49 mg/g, 81.26 mg/g이며, DPPH 라디칼 소거능을 조사한 결과 50~1,000 mg/L 농도에서 회화나무 꽃 추출물은$17.68{\pm}1.59{\sim}51.40{\pm}1.04%$, 열매 추출물은 $27.48{\pm}0.22{\sim}50.89{\pm}0.13%$, 가지 추출물은 $30.79{\pm}0.55{\sim}45.17{\pm}0.83%$ 범위의 소거 활성을 나타내었다. 또한 같은 농도에서 티로시나제 저해능과 PPE 저해능을 실험한 결과 회화나무 꽃 추출물은 $0.27{\pm}0.12{\sim}11.38{\pm}0.57%$, $3.70{\pm}1.23{\sim}7.28{\pm}1.01%$ 열매 추출물은 $0.27{\pm}0.02{\sim}0.82{\pm}0.27%$, $3.06{\pm}2.13{\sim}13.03{\pm}2.99%$, 가지 추출물은 $0.09{\pm}0.16{\sim}0.55{\pm}0.27%$, $6.00{\pm}0.96{\sim}9.71{\pm}0.44%$ 범위로 티로시나제 저해능은 꽃 추출물이 높게 나타났다. 본 연구에서 회화나무의 피부개선에 미치는 효능, 효과를 살펴본 결과 꽃, 열매, 가지 추출물이 각 부위별로 효과가 상이하게 나타남을 알 수 있었다.

Keywords

References

  1. K. S. Kim, Ph. D. Dissertation, Seoul Venture Univ., Seoul, Korea (2009).
  2. O. Wiedow, J. M. Schroder, H. Gregory, J. A. Young, and E. Christophers, An elastase specific inhibition of human skin, J. Biol. Chem., 265(25), 14791 (1990).
  3. H. Y. Jung, J. K. Han, J. H. Ha, Y. Kim, S. H. Oh, S. S. Kim, M. H. Jung, K. P. Choi, U. Y. Park, and H. Y. Lee, Antioxidant activities and skin-whitening effects of nano-encapsuled water extract from Rubus coreanus Miquel, Korean J. Med. Crop Sci., 17(2), 83 (2009).
  4. J. S. Hwang, Y. K. Cho, J. I. Kim, W. J. Park, and J. S. Lee, The effect of retinoids on crabp II mRNA induction and collagen synthesis in human dermal fibroblast, J. Soc. Cosmet. Sci. Korea, 23(3), 9 (1997).
  5. C. W. Lee, H. B. Pyo, Y. H. Cho, and S. M. Park, Effect of Korean black soybean seed on the cellular proliferation and the production of type III collagen in skin fibroblast, J. Soc. Cosmet. Sci. Korea, 24(3), 31 (1998).
  6. B. J. Kim, B. K. Jo, and J. H. Kim, A promising new antiwrinkle ingredient: pericarpium castaneae extracts, J. Soc. Cosmet. Sci. Korea, 25(4), 57 (1999).
  7. J. J. Cho, K. K. Lee, B. K. Cho, and J. D. Choi, Isolation and characterization of elastase inhibitor from Areca catechu, J. Soc. Cosmet. Sci. Korea, 35(1), 163 (2000).
  8. 생활한방민속약, 한국자연의학연구회, 36, 동부문화사, 대전 (1985).
  9. 동의보감, 동의보감국역위원회, 136, 법인문화사, 서울 (1999).
  10. K. J. Jung, Master's Thesis Dissertation, Suncheon Univ., Suncheon, Korea (2012).
  11. Y. J. Kim, J. A. Jung, S. H. Kwon, and H. W. Cho, 27th International Horticultural Congress & Exhibition, Seoul, 97 (2006).
  12. K. I. Moon, Master's Thesis Dissertation, Donshin Univ., Busan, Korea (2006).
  13. J. H. Lee, Master's Thesis Dissertation, Kangwon Univ., Chuncheon, Korea (2013).
  14. S. J. Park, E. S. Kim, Y. S. Choi, and J. D. Kim, Effcts of sophorae fructus on antioxidative activities and lipid levels in rats, J. Korean Soc. Food Sci. Nutr., 37(9), 1120 (2008). https://doi.org/10.3746/jkfn.2008.37.9.1120
  15. S. Y. Choi, S. H. Youn, and B. K. Min, Rexflavone (sophorae fructus extract) for menopausal symptoms in postmenopausal women and new aspects of isoflavones, Food Industry and Nutrition, 18(2), 17 (2013).
  16. O. Folin and W. Denis, On phosphotungastic phosphomolybdic compounds as color regents, J. Biol. Chem., 12(2), 239 (1912).
  17. Y. Fujita, I. Uehara, Y. Morimoto, M. Nakashima, and T. Hatano, Studies on inhibition mechanism of autoxidation by tannins and flavonoids. II. Inhibition mechanism of caffeetannins isolated from leaves of Artemisia species on lipoxygenase dependent lipid peroxidation, Yakugaku Zasshi, 108(2), 129 (1988). https://doi.org/10.1248/yakushi1947.108.2_129
  18. K. Tomita, N. Oda, M. Ohbayashi, H. Kamei, T. Miyaki, and T. Oki, A new screening method for melanin biosynthesis inhibitors using Streptomyces bikiniensis, J. Antibiot., 43(12), 1601 (1990). https://doi.org/10.7164/antibiotics.43.1601
  19. R. M. Facino, M. Carini, R. Stefani, G. Aldini, and L. Saibene, Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency, Arch. Pharm., 328(10), 720 (1995). https://doi.org/10.1002/ardp.19953281006
  20. C. H. Kang, Master's Thesis Dissertation, Kyemyung Univ., Daegu, Korea (2011).
  21. M. R. Han, N. W. Kim, and Y. S. Lee, Regular articles : anti-wrinkle and antioxidative effects of ethanolic extracts of inula flos, chrysanthemi flos and carthami flos, Journal of Investigative Cosmetology, 9(4), 361 (2013).
  22. E. A. Cho, Master's Thesis Dissertation, Seoul Univ., Seoul, Korea (2012).
  23. J. H. Jung and K. J. Kim, Experimental studies about the inhibitory effect on tyrosinase and elastase activities by various herb medicines, J. Korean Orient. Med. Ophthalmol. Otolaryngol. Dermato., 22(2), 82 (2009).
  24. E. J. Noh, Y. S. Kim, and B. K. Kim, Anti-wrinkle effect of Ligularia stenocephala, J. Korean Oil Chem. Soc., 26(2), 186 (2009).
  25. J. S. Lee, Y. J. Kwak, D. H. Lee, and N. M. Kim, Screening and extraction condition of anti-skin aging elastase inhibitor from medicinal plants, Korean J. Med. Crop Sci., 13(6), 213 (2005).