Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Changes in Ginsenosides Composition of Ginseng Leaf and Stem after an Ultrasonication Process

초음파 처리에 의한 인삼 잎과 줄기의 진세노사이드 성분 변화

  • Nam, Yun Min (The Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Shin, Ho June (The Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Yang, Byung Wook (Korean Ginseng Research Co. Ltd) ;
  • Park, Jong Dae (Korean Ginseng Research Co. Ltd) ;
  • Cho, Soon Hyun (Department of Pharmaceutical Quality Control, Daewon University College) ;
  • Kim, Hyoung Chun (College of Pharmacy, Kangwon National University) ;
  • Ko, Sung Kwon (The Department of Oriental Medical Food & Nutrition, Semyung University)
  • Received : 2016.11.06
  • Accepted : 2016.12.19
  • Published : 2016.12.30
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Abstract

The purpose of this study is to develop a new preparation process of ginseng leaf and stem extracts having high concentrations of ginsenoside Rg2, Rg3, Rg5, Rh1, a special component of red and black ginseng. Chemical transformation from ginseng saponin glycosides to prosapogenin was analyzed by the HPLC. Extracts of ginseng (Panax ginseng) leaf and stem were processed under several treatment conditions including ultrasonication treatments. The content of total saponin reached their heights at 17 hr (UGL-17) of ultrasonication treatment, followed by 16 hr (UGL-16) and 7 hr (UGL-7) of ultrasonication treatment at $100^{\circ}C$. UGL-17 findings show that the ginseng leaf and stem that had been processed with ultrasonication for 17 hours peaked in the level of Rg2, Rg3 and Rh1. In addition, UGL-16 contained ginsenoside Rg5 at high concentrations. It is thought that such results provide basic information in preparing ginseng leaf and stem extracts with functionality enhanced.

Keywords

References

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