대한방사성의약품학회지 (Journal of Radiopharmaceuticals and Molecular Probes)
- 제1권1호
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- Pages.9-14
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- 2015
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- 2384-1583(pISSN)
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- 2508-3848(eISSN)
DOI QR Code
Synthetic approaches toward [18F]Fluoromisonidazole as a hypoxia imaging maker
- Kwon, Young-Do (Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Cyclotron Research Center, Biomedical Research Institute, Chonbuk National University Medical School and Hospital) ;
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Lim, Seok Tae
(Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Cyclotron Research Center, Biomedical Research Institute, Chonbuk National University Medical School and Hospital) ;
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Jeong, Hwan-Jeong
(Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Cyclotron Research Center, Biomedical Research Institute, Chonbuk National University Medical School and Hospital) ;
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Sohn, Myung-Hee
(Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Cyclotron Research Center, Biomedical Research Institute, Chonbuk National University Medical School and Hospital) ;
- Kim, Hee-Kwon (Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Cyclotron Research Center, Biomedical Research Institute, Chonbuk National University Medical School and Hospital)
- 투고 : 2015.02.17
- 심사 : 2015.03.31
- 발행 : 2015.04.30
초록
Hypoxia has been shown in many tumors because of a reduced oxygen condition. A useful approach to detect hypoxia is to use molecular imaging. Positron emission tomography (PET), one of the biomedical molecular imaging tools, is the most common non-invasive technique for providing information about physiological and biological events such as diseases. In order to use the PET technique for healthcare, promising molecular probes such as PET tracers required. [