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Use of Natural Halloysite as a Functional Cosmetics Carrier

기능성 화장품의 캐리어로서 천연 할로이사이트의 활용

  • Suh, Yong Jae (Mineral Resources Research Division, Korea Institute of Geoscience and Mineral Resources, Nanomaterials Science and Engineering, Korea University of Science and Technology)
  • 서용재 (한국지질자원연구원 광물자원연구본부, 과학기술연합대학원대학교 나노재료공학전공)
  • Received : 2015.06.23
  • Accepted : 2015.06.27
  • Published : 2015.06.28

Abstract

Natural halloysite is mostly found in the form of a tubular structure with a 15-125 nm internal lumen. This kaolin clay can be used for encapsulating a liquid ingredient of cosmetics and for immobilizing an inorganic solid-phase ingredient. In this paper, the encapsulation and immobilization procedures are introduced and two example applications are reviewed to demonstrate the usefulness of halloysite as a cosmetics substrate. It may help attract more interest in cosmetic applications of halloysite and thus spur more research on the utilization of natural clays.

천연 할로이사이트는 대부분 지름 15-125 nm범위의 내강으로 이루어진 튜브 구조의 형태를 가진다. 이러한 튜브형 할로이사이트는 액체 성분의 화장품을 내부에 담지하거나 고체상의 무기물 성분을 고정화하는데 사용될 수 있다. 이 논문에서는 기능성 화장품 성분의 담지기술과 고정화기술을 소개하고 할로이사이트가 화장품용 기재로 유용하게 활용된 두 가지 연구 사례를 기술하였다. 이 논문이 천연 할로이사이트를 응용한 화장품 연구에 많은 관심을 불러모을 수 있기를 기대한다.

Keywords

References

  1. Barnard, A.S. (2010) One-to-one comparison of sunscreen efficacy, aesthetics and potential nanotoxicity. Nat. Nanotechnol., v.5, p.271-274. https://doi.org/10.1038/nnano.2010.25
  2. Barnard, A.S. (2011) Mapping the photocatalytic activity or potential free radical toxicity of nanoscale titania. Energy Environ. Sci., v.4, p.439-443. https://doi.org/10.1039/C0EE00287A
  3. Barry, B.W. (2001) Novel mechanisms and devices to enable successful transdermal drug delivery. Eur. J. Pharm. Sci., v.14, p.101-114. https://doi.org/10.1016/S0928-0987(01)00167-1
  4. Bennat, C. and Muller-Goymann, C. (2000) Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter. Int. J. Cosmet. Sci., v.22, p.271-283. https://doi.org/10.1046/j.1467-2494.2000.00009.x
  5. Byrne, R.S. and Deasy, P.B. (2005) Use of porous aluminosilicate pellets for drug delivery. J. Microencapsulation, v.22, p.423-437. https://doi.org/10.1080/02652040500100196
  6. Dunford, R., Salinaro, A., Cai, L., Serpone, N., Horikoshi, S., Hidaka, H. and Knowland, J. (1997) Chemical oxidation and DNA damage catalysed by inorganic sunscreen ingredients. FEBS Lett., v.418, p.87-90. https://doi.org/10.1016/S0014-5793(97)01356-2
  7. Hirakawa, T. and Nosaka, Y. (2002) Properties of $O_2$-and OH formed in $TiO_2$ aqueous suspensions by photocatalytic reaction and the influence of $H_2O_2$ and some ions. Langmuir, v.18, p.3247-3254. https://doi.org/10.1021/la015685a
  8. Hirakawa, T., Yawata, K. and Nosaka, Y. (2007) Photocatalytic reactivity for $O_2$ and OH radical formation in anatase and rutile $TiO_2$ suspension as the effect of $H_2O_2$ addition. Appl. Catal., A, v.325, p.105-111. https://doi.org/10.1016/j.apcata.2007.03.015
  9. Jiang, J., Oberdorster, G., Elder, A., Gelein, R., Mercer, P. and Biswas, P. (2008) Does nanoparticle activity depend upon size and crystal phase? Nanotoxicology, v.2, p.33-42. https://doi.org/10.1080/17435390701882478
  10. Joussein, E., Petit, S., Churchman, J., Theng, B., Righi, D. and Delvaux, B. (2005) Halloysite clay minerals-A review. Clay Miner., v.40, p.383-426. https://doi.org/10.1180/0009855054040180
  11. Kelly, H.M., Deasy, P.B., Ziaka, E. and Claffey, N. (2004) Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis. Int. J. Pharm., v.274, p.167-183. https://doi.org/10.1016/j.ijpharm.2004.01.019
  12. Lademann, J., Richter, H., Schanzer, S., Knorr, F., Meinke, M., Sterry, W. and Patzelt, A. (2011) Penetration and storage of particles in human skin: Perspectives and safety aspects. Eur. J. Pharm. Biopharm., v.77, p.465-468. https://doi.org/10.1016/j.ejpb.2010.10.015
  13. Lademann, J., Weigmann, H.-J., Rickmeyer, C., Barthelmes, H., Schaefer, H., Mueller, G. and Sterry, W. (1999) Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacology and Physiology, v.12, p.247-256. https://doi.org/10.1159/000066249
  14. Levis, S.R. and Deasy, P.B. (2002) Characterisation of halloysite for use as a microtubular drug delivery system. Int. J. Pharm., v.243, p.125-134. https://doi.org/10.1016/S0378-5173(02)00274-0
  15. Levis, S.R. and Deasy, P.B. (2003) Use of coated microtubular halloysite for the sustained release of diltiazem hydrochloride and propranolol hydrochloride. Int. J. Pharm., v.253, p.145-157. https://doi.org/10.1016/S0378-5173(02)00702-0
  16. Lvov, Y.M. and Price, R.R., 2007. Halloysite Nanotubules, a Novel Substrate for the Controlled Delivery of Bioactive Molecules, Bio-inorganic Hybrid Nanomaterials.
  17. Lvov, Y.M., Shchukin, D.G., Mohwald, H. and Price, R.R. (2008) Halloysite Clay Nanotubes for Controlled Release of Protective Agents. ACS Nano, v.2, p.814-820. https://doi.org/10.1021/nn800259q
  18. Menzel, F., Reinert, T., Vogt, J. and Butz, T. (2004) Investigations of percutaneous uptake of ultrafine $TiO_2$ particles at the high energy ion nanoprobe LIPSION. Nucl. Instrum. Methods Phys. Res., Sect. B, v.219-220, p.82-86. https://doi.org/10.1016/j.nimb.2004.01.032
  19. Murphy, G. (1999) Sunblocks: Mechanisms of action. Photodermatology, photoimmunology & photomedicine, v.15, p.34-36. https://doi.org/10.1111/j.1600-0781.1999.tb00051.x
  20. Nel, A., Xia, T., Madler, L. and Li, N. (2006) Toxic potential of materials at the nanolevel. Science, v.311, p.622-627. https://doi.org/10.1126/science.1114397
  21. Newman, M.D., Stotland, M. and Ellis, J.I. (2009) The safety of nanosized particles in titanium dioxide-and zinc oxide-based sunscreens. Journal of the American Academy of Dermatology, v.61, p.685-692. https://doi.org/10.1016/j.jaad.2009.02.051
  22. Oberdorster, G., Maynard, A., Donaldson, K., Castranova, V., Fitzpatrick, J., Ausman, K., Carter, J., Karn, B., Kreyling, W. and Lai, D. (2005) Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part. Fibre Toxicol., v.2, p.8. https://doi.org/10.1186/1743-8977-2-8
  23. Price, R.R., Gaber, B.P. and Lvov, Y. (2001) In-vitro release characteristics of tetracycline HCl, khellin and nicotinamide adenine dineculeotide from halloysite; a cylindrical mineral. J. Microencapsulation, v.18, p.713-722. https://doi.org/10.1080/02652040010019532
  24. Schueller, R. and Romanowski, P. (2003) Beginning Cosmetic Chemistry. Second ed. Allured Publishing Corporation, Carol Stream.
  25. Serpone, N., Dondi, D. and Albini, A. (2007) Inorganic and organic UV filters: Their role and efficacy in sunscreens and suncare products. Inorg. Chim. Acta, v.360, p.794-802. https://doi.org/10.1016/j.ica.2005.12.057
  26. Shchukin, D.G., Sukhorukov, G.B., Price, R.R. and Lvov, Y.M. (2005) Halloysite nanotubes as biomimetic nanoreactors. Small, v.1, p.510-513. https://doi.org/10.1002/smll.200400120
  27. Suh, Y., Kil, D., Chung, K., Abdullayev, E., Lvov, Y. and Mongayt, D. (2011) Natural nanocontainer for the controlled delivery of glycerol as a moisturizing agent. J. Nanosci. Nanotechnol., v.11, p.661-665. https://doi.org/10.1166/jnn.2011.3194
  28. Suh, Y.J. and Cho, K. (2015) Immobilization of nanoscale sunscreening agents onto natural halloysite micropowder. Mater. Trans., v.56, p.899-904. https://doi.org/10.2320/matertrans.M2015086
  29. Tadros, T.F., 2008. Colloids in Cosmetics and Personal Care, in: Tadros, T.F. (Ed.), Colloids and Interface Science Series. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
  30. Tinkle, S.S., Antonini, J.M., Rich, B.A., Roberts, J.R., Salmen, R., DePree, K. and Adkins, E.J. (2003) Skin as a route of exposure and sensitization in chronic beryllium disease. Environ. Health Perspect., v.111, p.1202-1208. https://doi.org/10.1289/ehp.5999
  31. van de Hulst, H.C. (1981) Light Scattering by Small Particles. Dover Publications, Mineola.
  32. Veerabadran, N.G., Mongayt, D., Torchilin, V., Price, R.R. and Lvov, Y.M. (2009) Organized shells on clay nanotubes for controlled release of macromolecules. Macromol. Rapid Commun., v.30, p.99-103. https://doi.org/10.1002/marc.200800510
  33. Veerabadran, N.G., Price, R.R. and Lvov, Y.M. (2007) Clay nanotubes for encapsulation and sustained release of drugs. Nano, v.02, p.115-120. https://doi.org/10.1142/S1793292007000441

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