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Verification of anti-oxidative activity of Aruncus dioicus, a native plant of Ulleungdo

울릉도 자생식물 삼나물(Aruncusdioicus)의 항산화 활성 검증

  • Kim, Dong-Hee (Team of Herbal Product Development, Korea Promotion Institute for Traditional Medicine Industry) ;
  • Moon, Yong-Sun (Department of Horticulture & Life Science, Yeungnam University) ;
  • Son, Jun-Ho (Team of Herbal Product Development, Korea Promotion Institute for Traditional Medicine Industry)
  • Received : 2015.03.09
  • Accepted : 2015.03.18
  • Published : 2015.03.31

Abstract

The extracts of Aruncus dioicus were investigated for anti-oxidant and biological activities in order to verify its potential as functional ingredients of cosmetic products. The ethyl acetate (EtOAc) extract of A. dioicus showed excellent scavenging activity using DPPH and ABTS anti-oxidant analysis at the $1,000{\mu}g/mL$ concentration. While tyrosinase inhibitory effect was measure for whitening assay and showed 59.2%, the suppression levels of elastase and collagenase were 56% and 90% respectively for anti-wrinkle activity. Therefore, it is plausible to conclude that A. dioicus extract, especially EtOAc fraction which has outstanding whitening, anti-oxidant, and anti-wrinkle activities, could be used as a new functional materials for cosmetics.

삼나물 추출물의 항산화 및 생리활성 효과를 검증하여 화장품의 기능성 소재로서의 가능성을 검증하였다. 항산화 실험 결과 삼나물의 ethyl acetate (EtOAc) 분획물 $1,000{\mu}g/mL$ 농도에서 DPPH, ABTS와 같은 전자 공여능 실험에서 가장 높은 활성을 나타났다. 미백효과 측정을 위한 tyrosinase 활성 억제도 삼나물 EtOAc 분획물에서 59.2%의 효과를 나타내었고, elastase 활성은 56% 그리고 collagenase 활성은 90% 저해효과로 항주름 효과가 검증되었다. 따라서 삼나물 추출물 특히 EtOAc 분획물은 우수한 항산화, 항주름 및 미백 생리활성으로 화장품의 새로운 기능성 소재로서 응용이 가능함을 확인하였다.

Keywords

References

  1. An BJ, Lee CE, Son JH, Lee JY, Choi CH, Park TS (2005) Antioxidant, anticancer and tyrosinase inhibition activities of extracts from Rhododendron mucronulatum T. J Kor Soc Appl Biol Chem 48:280-284
  2. Blois MS (1958) Antioxidant determination by the use of a stable free radical. Nature 181:1199-1120 https://doi.org/10.1038/1811199a0
  3. Cannell RJP, Kellan SJ, Owsianks AM, Walker JM (1988) Results of a large scale screen of microalgae for the production of protease inhibitors. Planta Media 54:10-14 https://doi.org/10.1055/s-2006-962319
  4. Invengar R, Mcevily AJ (1992) Anti-browning agents: alternatives to the use of sulfites in foods. Trends Food Sic Technol 3:60-63 https://doi.org/10.1016/0924-2244(92)90131-F
  5. Jeroma SP, Gabrielle L, Raul F (1998) Identification of collagen fibrils in scleroderma skin. J Invest Dermatol 90:48-54
  6. Kang KS (2007) The Evaluation of Anti-wrinkle Effects in Oriental Herb Extract. J Life sci 17:1147-1151 https://doi.org/10.5352/JLS.2007.17.8.1147
  7. Kim DH, Moon YS, AN BJ, Son JH (2012) Potent anti-aging activity of Aruncus dioicus, a native plant of Ulleung-do, South Korea, in CCD-986sk fibroblsts via suppression of matrix metalloproteinases. J Nat Med 66:631-636 https://doi.org/10.1007/s11418-012-0633-3
  8. Kim DH, Moon YS, Park TS, Son JH (2013) Potent whitening activity of Aruncus dioicus extract in B16F10 melanoma cell by suppression of melanin biosynthesis. Kor J Kort Sci Technol 31:813-820
  9. Kim HK, Kim YE, Do JR, LEE YC, Lee BY (1995) Antioxidative activity and physiological activity of some Korean medicinal plants. J Food Sci Technol 27:80-86
  10. Kim MJ, Kim JY, Choi SW, Hong JT, Yoon KS (2004) Anti-wrinkle effect of safflower (Cathamus tinctorius) seed extract. J Soc Cosmet Sci Kor 30:15-22
  11. Kwak YJ, Lee DH, Kim NM, Lee JS (2005) Screening and extraction condition of anti-skin aging elastase inhibitor from medicinal plants. Kor J Medi Crop Soc 13:213-216
  12. Kwon HN, Park JR, Jeon JR (2008) Antioxidative and hepatoprotective effects of Acer tegmentosum M. extracts. J Kor Soci Food Sci Nutri 37:1389-1394 https://doi.org/10.3746/jkfn.2008.37.11.1389
  13. Lee BB, Park SR (2008) Antioxidant activity and inhibition activity against a glucosidase of Viola mandshurica extracts. J Kor Soci Food Sci Nutri 37:405-409 https://doi.org/10.3746/jkfn.2008.37.4.405
  14. Lee CB (2003) Coloured flora of Korea. (Ed 1st) Hyangmoonsa, Seoul, Korea
  15. Lee JY, An BJ (2012) Whitening and Anti-wrinkling Effects of Fractions from Prunus persica Flos. Kor J Microbiol Biotechnol 40:364-370 https://doi.org/10.4014/kjmb.1207.07007
  16. Lee JY, Yu MR, An BJ (2010) Comparison of biological activity between Nelumbo nucifera G. extracts and cosmetics adding Nelumbo nucifera G. J Life Sci 20:1241-1248 https://doi.org/10.5352/JLS.2010.20.8.1241
  17. Lee NH, Yang HC, Bu HJ, Jung DS, Lee SJ, Riu KZ (2001) Screening of the tyrosinase inhibition and hyaluronidase inhibition activities and radical scavenging effects using plants in Cheju. Kor J Pharma 32:175-180
  18. Lee SY, An JH, Cho HY (2003) Isolation and characterization of MMP-1 inhibitor peptide from Crataegus pinnatifida Bunge in fibroblast cell line HS68 cells. J Kor Soc Agric Chem Biotechnol 46:60-65
  19. Oh HI, Park HB, Ju MS, Jung SY, Oh MS (2010) Comparative study of anti-oxidant and anti-inflammatory activities between Curcumae longae radix and Curcumae longae rhizoma. Kor J Herbol 25:83-91
  20. Park K, Lee JP (2008) Protective effects of resveratrol on UVB-irradiated HaCaT cells through attenuation of the caspase pathway. Oncol Rep 19:413-417
  21. Roberta R, Nicoletta P, Anna P, Ananth P, Min Y, Catherine RE (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free radical boil Medi 26:1231-1237 https://doi.org/10.1016/S0891-5849(98)00315-3
  22. Shin JW, Lee SI, Woo MH Kim SD (2008) Effect of Ethanol Extracts of Goat's beard on streptoxotocin induced diabetic symptoms and oxidative stress in rats. J East Asian Soc Die Life 18:939-948
  23. Voegeli R (1996) Elastase and tryptase determination on human skin surface. Cos Toil 111:51-58
  24. Yagi A, Kanbara T, Morinobu N (1986) The effect of tyrosinase inhibition for aloe. Planta Media 3981:517-519

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