Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Effects of Low Level Laser Treatment Applied to KI 1 on the Gait Behavior in the Rat Model of CFA-Induced Arthritis

흰쥐 관절염 모델에서 용천 저출력 레이저 자극이 보행행동에 미치는 영향

  • Ji, Byeong Uk (Division of Meridian and Structural Medicine, School of Korean Medicine, Pusan National University) ;
  • Li, Chengjin (Division of Meridian and Structural Medicine, School of Korean Medicine, Pusan National University) ;
  • Lee, Ji Eun (Division of Meridian and Structural Medicine, School of Korean Medicine, Pusan National University) ;
  • Koo, Sungtae (Division of Meridian and Structural Medicine, School of Korean Medicine, Pusan National University)
  • 지병욱 (부산대학교 한의학전문대학원 경락구조의학부) ;
  • 이성금 (부산대학교 한의학전문대학원 경락구조의학부) ;
  • 이지은 (부산대학교 한의학전문대학원 경락구조의학부) ;
  • 구성태 (부산대학교 한의학전문대학원 경락구조의학부)
  • Received : 2015.03.06
  • Accepted : 2015.03.17
  • Published : 2015.03.27
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Abstract

Objectives : The aim of the study is to investigate the effects of low level laser treatment (LLLT) on the gait behavior in the rat model of arthritis. Methods : Knee arthritis was induced by the injection of $125{\mu}l$ of Complete Freund's Adjuvant(CFA) into the right hind knee joint cavity. Arthritic rats were divided 3 groups; arthritis group was used for control(CON), 10 min of laser treated group(LSR10), and 30 min of laser treated group(LSR30). LLLT was applied to KI 1 for 11 times under gaseous anesthesia. We performed several analyses under catwalk test including stand and swing time, duty cycle of paw steps, intensity and print area of steps, and stride length. Results : Stand and duty cycle of paw steps were increased significantly at 12 days after arthritis induction in LSR30 group. Swing time was decreased significantly at 12 days after arthritis induction in LSR10 group. In the analysis of intensity, print area and stride length, however, results did not show statistical significance during the time point of experiments. Conclusions : The data suggest that LLLT on the rat model of CFA induced arthritis showed beneficial effects by increase of stand time and duty cycle of paw steps and decrease of swing time. Therefore, LLLT could be useful option to improve gait discomfort in arthritis patients.

Keywords

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