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Effects of Sunsik Prepared through Steaming-Drying Cycles on Blood Glucose and Inflammatory Marker in Rats Fed High Fat

증포 횟수를 달리하여 만든 선식을 첨가한 고지방식이가 비만 쥐의 혈당과 염증지표에 미치는 영향

  • Hwang, Kyung-Hee (Dept. of Herbal Food Science, Graduate School, Daegu Haany University) ;
  • Kong, Hyun-Joo (Dept. of Herbal Food Science, Graduate School, Daegu Haany University) ;
  • Lee, Eon-Hee (Dept. of Food Science and Nutrition, Kyungpook National University) ;
  • Choi, Eun-Mi (Dept. of Food Science and Nutrition, Kyungpook National University) ;
  • Hwang, Su-Jung (Faculty of Herbal Food Cuisine and Nutrition, Daegu Haany University) ;
  • Jang, Jung-Hyeon (Division of Cosmetology, Dong-Eui Institute of Technology) ;
  • Yang, Kyung-Mi (Faculty of Herbal Food Cuisine and Nutrition, Daegu Haany University)
  • 황경희 (대구한의대학교 일반대학원 한방식품학과) ;
  • 공현주 (대구한의대학교 일반대학원 한방식품학과) ;
  • 이언희 (영남대학교 일반대학원 식품영양학과) ;
  • 최은미 (영남대학교 일반대학원 식품영양학과) ;
  • 황수정 (대구한의대학교 한방식품조리영양학부) ;
  • 장정현 (부산동의과학대학교 피부미용계열) ;
  • 양경미 (대구한의대학교 한방식품조리영양학부)
  • Received : 2014.10.28
  • Accepted : 2015.02.28
  • Published : 2015.02.27

Abstract

This study was conducted to evaluate the effects of Sunsik prepared by steaming -drying cycles- on blood glucose and inflammatory markers in high fat diet-induced obese rats. The experimental animals were divided into five groups and subjected to diets for 8 weeks; normal diet (control), high fat diet (HF), and high fat diet+10% supplementation of Sunsik (1HF, 3HF, 7HF, 9HF). The results showed body weight, food efficiency ratio, blood glucose and insulin levels of high fat diet groups were significantly higher than those of the control group. Increased glucose levels by high fat diet were reduced to normal levels by the four Sunsik supplementations. Insulin resistance (HOMA-IR) of the HF group was significantly higher than those of the control group, whereas supplementation with the four types of Sunsik reduced insulin resistance to similar levels as the control group. Increased insulin secretion and leptin levels of high fat diet-induced obese rats were significantly reduced by supplementation with the four types of Sunsik. C-reactive protein (CRP) of inflammation related components was significantly higher than the control group. However, increased CRP concentration by high fat diet was significantly reduced by supplementation with Sunsik.

Keywords

References

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