Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
권호 표지
DOI QR코드

DOI QR Code

Quality of life following surgical treatment of oral cancers

  • Received : 2014.07.05
  • Accepted : 2014.11.21
  • Published : 2015.02.28
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: Quality of life (QoL) studies provide information about the impact of disease, the treatment of symptoms, and outcomes following treatment. The present study aims to evaluate the postoperative QoL of patients treated for oral cancer in a Nigerian government tertiary hospital. Materials and Methods: A prospective study on consenting patients with oral cancer was undertaken at Aminu Kano Teaching Hospital, Kano, Nigeria. The subjects completed the University of Washington QoL (UW-QoL) questionnaire one day prior to surgery and postoperatively after 7 days, 1 month, 3 months, and 6 months. Results: Sixty-eight patients with oral cancer were recruited. Of these, 38 were males, and 30 were females (male : female, 1.3 : 1). Twenty-four patients (12 males and 12 females) underwent surgery and completed postoperative QoL assessment using the UW-QoL questionnaire. Preoperative QoL mean score was 2.21, while postoperative mean scores after 1 week, 1 month, 3 months, and 6 months were 3.67, 3.46, 2.82, and 2.61, respectively. Conclusion: An improvement in QoL following surgical treatment for patients with oral cancer was observed. 'Appearance,' 'recreation,' and 'chewing' were identified as the most important determinants of postoperative QoL in patients with oral cancer in our study.

Keywords

References

  1. Marx RE, Stern D. Oral and maxillofacial pathology: a rationale for diagnosis and treatment. Chicago: Quintessence Publishing; 2003:283-93.
  2. Tang XH, Knudsen B, Bemis D, Tickoo S, Gudas LJ. Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. Clin Cancer Res 2004;10:301-13. https://doi.org/10.1158/1078-0432.CCR-0999-3
  3. Hotary K, Allen E, Punturieri A, Yana I, Weiss SJ. Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol 2000;149:1309-23. https://doi.org/10.1083/jcb.149.6.1309
  4. Kaplan RN, Rafii S, Lyden D. Preparing the "soil": the premetastatic niche. Cancer Res 2006;66:11089-93. https://doi.org/10.1158/0008-5472.CAN-06-2407
  5. Carnelio S, Rodrigues G. Oral cancer at a glance. Internet J Dent Sci [Internet]. 2003;1(2) [cited 2013 Mar 21]. Available from: https://ispub.com/IJDS/1/2/5720.
  6. SEER cancer statistics review, 1975-2005 [Internet]. Bethesda (MD): National Cancer Institute [cited 2009 Jan 26]. Available from: http://seer.cancer.gov/archive/csr/1975_2005.
  7. World Health Organization (WHO). International statistical classification of diseases and related health problems. 10th revision. Geneva: WHO; 1992:42-57.
  8. Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 1993;54:594-606. https://doi.org/10.1002/ijc.2910540413
  9. The Oral Cancer Foundation [Internet]. Newport Beach (CA): The Oral Cancer Foundation [cited 2006 May 28]. Available from: http://www.oralcancerfoundation.org.
  10. Levi F, Lucchini F, La Vecchia C. Worldwide patterns of cancer mortality, 1985-89. Eur J Cancer Prev 1994;3:109-43.
  11. Rogers SN, Laher SH, Overend L, Lowe D. Importance-rating using the University of Washington quality of life questionnaire in patients treated by primary surgery for oral and oro-pharyngeal cancer. J Craniomaxillofac Surg 2002;30:125-32. https://doi.org/10.1054/jcms.2001.0273
  12. Goldspiel BR, Green L, Calis KA. Human gene therapy. Clin Pharm 1993;12:488-505.
  13. Arotiba GT, Ladeinde AL, Oyeneyin JO, Nwawolo CC, Banjo AA, Ajayi OF. Malignant orofacial neoplasms in Lagos, Nigeria. East Afr Med J 2006;83:62-8.
  14. Ajayi OF, Adeyemo WL, Ladeinde AL, Ogunlewe MO, Effiom OA, Omitola OG, et al. Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital. Int J Oral Maxillofac Surg 2007;36:403-8. https://doi.org/10.1016/j.ijom.2007.01.007
  15. Adekeye EO, Asamoa E, Cohen B. Intraoral carcinoma in Nigeria: a review of 137 cases. Ann R Coll Surg Engl 1985;67:180-2.
  16. Ugboko V, Ajike S, Olasoji H, Pindiga H, Adebiyi E, Omoniyi-Esan G, et al. Primary orofacial squamous cell carcinoma: a multicenter Nigerian study. Internet J Dent Sci [Internet]. 2003;1(2) [cited 2013 May 5]. Available from: https://ispub.com/IJDS/1/2/10778.
  17. Arotiba JT, Obiechina AE, Fasola OA, Fawole OI, Ajagbe HA. Oral squamous cell carcinoma: a review of 246 Nigerian cases. Afr J Med Med Sci 1999;28:141-4.
  18. Lippman SM, Sudbo J, Hong WK. Oral cancer prevention and the evolution of molecular-targeted drug development. J Clin Oncol 2005;23:346-56. https://doi.org/10.1200/JCO.2005.09.128
  19. Kanatas AN, Rogers SN. A national survey of health-related quality of life questionnaires in head and neck oncology. Ann R Coll Surg Engl 2004;86:6-10.
  20. Rogers SN, Ahad SA, Murphy AP. A structured review and theme analysis of papers published on 'quality of life' in head and neck cancer: 2000-2005. Oral Oncol 2007;43:843-68. https://doi.org/10.1016/j.oraloncology.2007.02.006
  21. Atchison KA, Shetty V, Belin TR, Der-Martirosian C, Leathers R, Black E, et al. Using patient self-report data to evaluate orofacial surgical outcomes. Community Dent Oral Epidemiol 2006;34:93-102. https://doi.org/10.1111/j.1600-0528.2006.00260.x

Cited by

  1. Assessment of oral cancer pain, anxiety, and quality of life of oral squamous cell carcinoma patients with invasive treatment procedure vol.22, pp.1, 2015, https://doi.org/10.1007/s10006-018-0672-3
  2. Clinical Profile and Quality of Life Assessment of Oral Cancer Patients Following Nasolabial Flap Reconstruction Surgery vol.72, pp.2, 2020, https://doi.org/10.1007/s12070-019-01760-5
  3. Clinical yoga trial aim to improve quality of life at advanced stages of oral cancer vol.17, pp.3, 2015, https://doi.org/10.1007/s11332-021-00732-z