Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Effect of Anti-Skin Wrinkle and Antioxidant of Agastache rugosa Kentz through Fermentation Process of the lactic acid

유산균 발효 배초향 추출물의 항산화 활성과 주름개선 효능

  • Kim, Nam Young (Department of Medical Biomaterials Engineering, Kangwon National University) ;
  • Park, Dae Su (Department of Food Science and Engineering, Seowon University) ;
  • Lee, Hyeon Yong (Department of Food Science and Engineering, Seowon University)
  • 김남영 (강원대학교 생물의소재공학과) ;
  • 박대수 (서원대학교 식품공학과) ;
  • 이현용 (서원대학교 식품공학과)
  • Received : 2014.11.10
  • Accepted : 2015.01.22
  • Published : 2015.02.28
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Abstract

This study was to investigate anti-skin wrinkle effect of Agastache rugosa Kentz extracts by extraction processes. In the comparison of the effect of the solvent extraction, the extracts by 70% ethanol (EE) showed better biological activities that those by hot water. Therefore, further fermented Agastache rugosa was applied to 70% ethanol extraction process (FEE). FEE showed higher DPPH scavenging activity of 62.98% than EE's 62.71% at $1.0mg/m{\ell}$, but there was no significant. Elastase inhibition was measured 23.0% from FEE at $1.0mg/m{\ell}$. Cytotoxicity showed the highest 16.26% from FEE, this value is safe in the cell experiment. Collagen production showed $113.1ng/m{\ell}$ from FEE, on the other hand EE was measured $77.4ng/m{\ell}$ in adding $1.0mg/m{\ell}$. MMP-1 production was observed $1398pg/m{\ell}$ from FEE and EE was measured $1632pg/m{\ell}$. These results were found the highest antioxidant and anti-wrinkle effect. As a result, it was also confirmed that anti-skin wrinkle activities of the Agastache rugosa Kentz extract was correlated with anti-oxidant activities.

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References

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