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Influence of Hazy Weather on Patient Presentation with Respiratory Diseases in Beijing, China

  • Ping, Jie (Department of Neurology, The 263th Hospital of Chinese PLA)
  • Published : 2015.02.25

Abstract

Background: Chronic respiratory disease is an important factor for development of lung cancer. To explore the influence of hazy weather on respiratory diseases and its variation the present study was conducted. Materials and Methods: Data from air pollution surveillance from January to October 2014 and case records of visiting patients in the $263^{th}$ Hospital of Chinese PLA in the corresponding period were collected to analyze the relevance between different degrees of air pollution (hazy weather) and the number of visiting patients in Department of Respiratory Disease. Results: Air quality index (AQI) of hazy weather had significantly positive association with particulate matter 2.5 ($PM_{2.5}$) and the number of patients with 5 kinds of respiratory diseases i and different pollutants had distinct influences on various respiratory diseases. Conclusions: The degree of air pollution in Beijing City is in close association with the number of patients with respiratory diseases, in which $PM_{2.5}$ and $SO_2$ are in more significant influences on all respiratory diseases. This could have essential implications for lung cancer development in China.

Keywords

References

  1. Annesi-Maesano I, Moreau D, Caillaud D, et al (2007). Residential proximity fine particles related to allergic sensitisation and asthma in primary school children. Respir Med, 101, 1721-9. https://doi.org/10.1016/j.rmed.2007.02.022
  2. Bargagli E, Olivieri C, Bennett D, et al (2009). Oxidative stress in the pathogenesis of diffuse lung diseases: a review. Respir Med, 103, 1245-56. https://doi.org/10.1016/j.rmed.2009.04.014
  3. Brook RD, Rajagopalan S, Pope CA 3rd, et al (2010). Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American heart association. Circulation, 121, 2331-78. https://doi.org/10.1161/CIR.0b013e3181dbece1
  4. Brauer M1, Amann M, Burnett RT, et al (2012). Exposure assessment for estimation of the global burden of disease attributable to outdoor air pollution. Environ Sci Technol, 46, 652-60. https://doi.org/10.1021/es2025752
  5. Deng X, Zhang F, Rui W, et al (2013). PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells. Toxicol In Vitro, 27, 1762-70. https://doi.org/10.1016/j.tiv.2013.05.004
  6. Deng X, Rui W, Zhang F, et al (2013). PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells. Cell Biol Toxicol, 29, 143-57. https://doi.org/10.1007/s10565-013-9242-5
  7. Denholm R, Schuz J, Straif K, et al (2014). Is previous respiratory disease a risk factor for lung cancer? Am J Respir Crit Care Med, 190, 549-59. https://doi.org/10.1164/rccm.201402-0338OC
  8. Guo LJ, Zhao A, Chen RJ, et al (2014). Association between Ambient Air Pollution and Outpatient Visits for Acute Bronchitis in a Chinese City. Biomed Environ Sci, 27, 833-40.
  9. Jassal MS (2014). Pediatric asthma and ambient pollutant levels in industrializing nations. Int Health, [Epub ahead of print].
  10. Katanoda K, Sobue T, Satoh H, et al (2011). An association between long-term exposure to ambient air pollution and mortality from lung cancer and respiratory diseases in Japan. J Epidemiol, 21, 132-43. https://doi.org/10.2188/jea.JE20100098
  11. Kaur S, Gill MS, Gupta K, et al (2013). Effect of occupation on lipid peroxidation and antioxidant status in coal-fired thermal plant workers. Int J Appl Basic Med Res, 3, 93-7. https://doi.org/10.4103/2229-516X.117065
  12. Lippmann M, Gordon T, Chen LC (2005). Effects of subchronic exposures to concentrated ambient particles in mice. IX. Integral assessment and human health implications of subchronic exposures of mice to CAPs. Inhal Toxicol, 17, 255-61. https://doi.org/10.1080/08958370590912941
  13. Lundborg M, Dahlen SE, Johard U, et al (2006). Aggregates of ultrafine particles impair phagocytosis of microorganisms by human alveolar macrophages. Environ Res, 100, 197-204. https://doi.org/10.1016/j.envres.2005.08.007
  14. Laumbach RJ (2010). Outdoor air pollutants and patient health. Am Fam Physician, 81, 175-80.
  15. Lim SS, Vos T, Flaxman AD, et al (2012). A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380, 2224-60. https://doi.org/10.1016/S0140-6736(12)61766-8
  16. McClellan RO (2012). Role of science and judgment in setting national ambient air quality standards: how low is low enough? Air Qual Atmos Health, 5, 243-58. https://doi.org/10.1007/s11869-011-0147-2
  17. Meng X, Ma Y, Chen R, et al (2013). Size-fractionated particle number concentrations and daily mortality in a Chinese city. Environ Health Perspect, 121, 1174-8.
  18. Oyana TJ, Rivers PA (2005). Geographic variations of childhood asthma hospitalization and outpatient visits and proximity to ambient pollution sources at a U.S.-Canada border crossing. Int J Health Geogr, 4, 14. https://doi.org/10.1186/1476-072X-4-14
  19. Petroeschevsky A, Simpson RW, Thalib L, et al (2001). Associations between outdoor air pollution and hospital admissions in Brisbane, Australia. Arch Environ Health, 56, 37-52. https://doi.org/10.1080/00039890109604053
  20. Rouse RL, Murphy G, Boudreaux MJ, et al (2008). Soot nanoparticles promote biotransformation, oxidative stress, and inflammation in murine lungs. Am J Respir Cell Mol Biol, 39, 198-207. https://doi.org/10.1165/rcmb.2008-0057OC
  21. Ruckerl R, Hampel R, Breitner S, et al (2014). Associations between ambient air pollution and blood markers of inflammation and coagulation/fibrinolysis in susceptible populations. Environ Int, 70, 32-49. https://doi.org/10.1016/j.envint.2014.05.013
  22. Rizzo AM, Corsetto PA1, Farina F, et al (2014). Repeated intratracheal instillation of PM10 induces lipid reshaping in lung parenchyma and in extra-pulmonary tissues. PLoS One, 9, 106855. https://doi.org/10.1371/journal.pone.0106855
  23. Traversi D, Cervella P, Gilli G (2014). Evaluating the genotoxicity of urban PM2.5 using PCR-based methods in human lung cells and the Salmonella TA98 reverse test. Environ Sci Pollut Res Int, [Epub ahead of print].
  24. Wagner U, Staats P, Fehmann HC, et al (2006). Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD). J Occup Med Toxicol, 1, 12. https://doi.org/10.1186/1745-6673-1-12
  25. Wang KY, Chau TT (2013). An association between air pollution and daily outpatient visits for respiratory disease in a heavy industry area. PLoS One, 8, 75220. https://doi.org/10.1371/journal.pone.0075220

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