Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Temperature-Range-Dependent Optimization of Noninvasive MR Thermometry Methods

온도범위에 따른 비침습적 자기공명 온도측정방법의 최적화

  • 김종민 (고려대학교 전자 및 정보공학과) ;
  • ;
  • 조영승 (고려대학교 전자 및 정보공학과) ;
  • ;
  • 김정희 (한국기초과학지원연구원) ;
  • 이철현 (한국기초과학지원연구원) ;
  • 오창현 (고려대학교 전자 및 정보공학과)
  • Received : 2015.10.22
  • Accepted : 2015.12.08
  • Published : 2015.12.31
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Abstract

Noninvasive temperature monitoring is feasible with Magnetic Resonance Imaging (MRI) based on temperature sensitive MR parameters such as $T_1$ and $T_2$ relaxation times, Proton Resonance Frequency shift (PRFs), diffusion, exchange process, magnetization transfer contrast, chemical exchange saturation transfer, etc. While the temperature monitoring is very useful to guide the thermal treatment such as RF hyperthermia or thermal ablation, the optimization of the MR thermometry method is essential because the range of temperature measurement depends on the choice of the measurement methods. Useful temperature range depends on the purpose of treatment methods, for example, $42^{\circ}C$ to $45^{\circ}C$ for RF hyperthermia and over $50^{\circ}C$ for thermal ablation. In this paper, MR thermometry methods using $T_1$ and $T_2$ relaxation times and PRFs-based MR thermometry are tried on a 3.0 T MRI system and their results are reported and compared. In addition, the scanning protocol and temperature calculation algorithms from $T_1$ and $T_2$ relaxation times and PRFs are optimized for the different temperature ranges for the purpose of RF hyperthermia and/or thermal ablation.

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References

  1. C.J. Lewa, and Z. Majewska, "Temperature relationships of proton spin-lattice relaxation time T1 in biological tissues," Bulletin Du Cancer, vol. 67, no. 5, pp. 525-530, 1979.
  2. S.J. Graham, M.J. Bronskill, and M. Henkelman, "Time and temperature dependence of MR parameters during thermal coagulation of ex vivo rabbit muscle," Magn Reson Med, vol. 39, no. 2, pp. 198-203, 1998. https://doi.org/10.1002/mrm.1910390206
  3. Y. Ishihara, A. Calderon, H. Watanabe, K. Okamoto, Y. Suzuki, K. Kuroda, and Y. Suzuki, "A precise and fast temperature mapping using water proton chemical shift," Magn Reson Med, vol. 34, no. 6, pp. 814-823, 1995. https://doi.org/10.1002/mrm.1910340606
  4. M.E. Moseley, Y. Cohen, J. Mintorovitc, L. Chileuitt, H. Shimizu, J. Kucharczyk, M.F. Wendlan, and P.R. Weinstein, "Early detection of regional cerebral ischemia in cats: comparison of diffusion?and T2?weighted MRI and spectroscopy," Magn Reson Med, vol. 14, no. 2, pp. 330-346, 1990. https://doi.org/10.1002/mrm.1910140218
  5. I.R. Young, J.W. Hand, A. Oatridge, and M.V. Prior, "Modeling and observation of temperature changes in vivo using MRI," Mag Reson Med, vol. 32, no. 3, pp. 358-369, 1994. https://doi.org/10.1002/mrm.1910320311
  6. V. Rieke, and K.B. Pauly, "MR thermometry," J Magn Reson Imag, vol. 27, no. 2, pp. 376-390, 2008. https://doi.org/10.1002/jmri.21265
  7. S. Oh, Y.C. Ryu, G. Carluccio, C.T. Sica, and C.M. Collins, "Measurement of SAR?induced temperature increase in a phantom and in vivo with comparison to numerical simulation," Magn Reson Med, vol. 71, no. 5, pp. 1923-1931, 2014. https://doi.org/10.1002/mrm.24820
  8. R.M. Goldstein, H.A. Zebker, and C.L. Werner, "Satellite radar interferometry: Two-dimensional phase unwrapping," Radio Sci, vol. 23, no. 4, pp. 713-720, 1988. https://doi.org/10.1029/RS023i004p00713
  9. J.D. Poorter, "Noninvasive MRI thermometry with the proton resonance frequency method: study of susceptibility effects," Mag Reson Med, vol. 34, no. 3, pp. 359-367, 1995. https://doi.org/10.1002/mrm.1910340313
  10. P.A. Bottomley, T.H. Foster, R.E Argersinger, and L.M. Pfeifer, "A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100 MHz: dependence on tissue type, NMR frequency, temperature, species, excision, and age," Med Phys, vol. 11, pp. 425-448, 1984. https://doi.org/10.1118/1.595535
  11. A.P. Crawley, and R.M. Henkelman, "A Comparison of One-Shot and Recovery Methods in T1 Imaging," Magn Reson Med, vol. 7, no. 1, pp. 23-24, 1988. https://doi.org/10.1002/mrm.1910070104
  12. I. Kay, and R.M. Henkelman, "Practical Implementation and Optimization of One-Shot T1 Imaging," Magn Reson Med, vol. 22, no. 2, pp. 414-424, 1991. https://doi.org/10.1002/mrm.1910220249
  13. E.K. Fram, R.J. Herfkens, G.A. Johnson, G.H. Glover, J.P. Karis, A. Shimakawa, T.G. Perkins, and N.J. Pelc, "Rapid calculation of T1 using variable flip angle gradient refocused imaging," Magn Reson Imag, vol. 5, no. 3, pp. 201-208, 1987. https://doi.org/10.1016/0730-725X(87)90021-X
  14. N. Stikov, C.L. Tardif and J.K. Barral, "T1 mapping: Methods and challenges," in Proc. ISMRM 19th Annual meeting and exhibition 2011, Montreal, Canada, May 2011, p. 4684.
  15. H.-J. Kim, S. Kumar, J.-H. Han, J.-M. Kim, J.-S. Yoon, S.-K. Lee, C. Lee and C.-H. Oh, "MR compatible electrode for RF hyperthermia with capacitive coupling: Feasibility demonstration," in Proc. ISMRM 23rd Annual meeting and exhibition 2015, Toronto, Canada, Jun. 2015, p. 537-551.