Journal of Food Hygiene and Safety (한국식품위생안전성학회지)

The Korean Society of Food Hygiene and Safety (한국식품위생안전성학회)
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Antimicrobial Activity of Lactobacillus plantarum LP2 against Helicobacter pylori

Lactobacillus plantarum LP2 균주의 Helicobacter pylori 억제효과

  • Kim, Tae-Jung (Department of Biotechnology, Korea National University of Transportation) ;
  • Moon, Gi-Seong (Department of Biotechnology, Korea National University of Transportation)
  • 김태중 (한국교통대학교 생명공학과) ;
  • 문기성 (한국교통대학교 생명공학과)
  • Received : 2015.11.09
  • Accepted : 2015.11.25
  • Published : 2015.12.30
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Abstract

A lactic acid bacterium LP2 strain, which was previously isolated from a natural cheese, was confirmed to produce 1,4-dihydroxy-2-naphthoic acid (DHNA), a bifidogenic growth factor. The strain was identified as Lactobacillus plantarum (99% identity) by a homology search of the 16S rRNA gene sequence and named Lactobacillus plantarum LP2. The culture supernatant of the strain presented an antimicrobial activity against Helicobacter pylori KCTC 12083, where the DHNA might have influenced on the activity.

비피도박테리아 증식인자인 1,4-dihydroxy-2-naphthoic acid 생산 유산균주 LP2가 선행연구에서 자연치즈로부터 분리되었다. LP2 균주는16S rRNA 유전자 염기서열 분석에 의한 균주동정에서 Lactobacillus plantarum(99% 일치율)과 가장 높은 상동성을 나타내어 Lactobacillus plantarum LP2 균주로 명명하였다. LP2 균주의 배양 상등액은 Helicobacter pylori KCTC 12083 균주에 대하여 항균활성을 나타내었으며 이는 생산된 DHNA에 기인하는 것으로 추측되었다.

Keywords

References

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