References
- Ajuebor, M.N., Hogaboam, C.M., Le, T., and Swain, M.G. (2003). CC chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse. J. Immunol. 170, 5252-5259. https://doi.org/10.4049/jimmunol.170.10.5252
- Austenaa, L.M., Carlsen, H., Hollung, K., Blomhoff, H.K., and Blomhoff, R. (2009). Retinoic acid dampens LPS-induced NFkappaB activity: results from human monoblasts and in vivo imaging of NF-kappaB reporter mice. J. Nutr. Biochem. 20, 726-734. https://doi.org/10.1016/j.jnutbio.2008.07.002
- Bruhl, H., Cihak, J., Schneider, M.A., Plachy, J., Rupp, T., Wenzel, I., Shakarami, M., Milz, S., Ellwart, J.W., Stangassinger, M., et al. (2004). Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells. J. Immunol. 172, 890-898. https://doi.org/10.4049/jimmunol.172.2.890
- Choi, Y.S., Lee, J., Lee, H.W., Chang, D.Y., Sung, P.S., Jung, M.K., Park, J.Y., Kim, J.K., Lee, J.I., Park, H., et al. (2014). Liver injury in acute hepatitis A is associated with decreased frequency of regulatory T cells caused by Fas-mediated apoptosis. Gut 64, 1303-1313.
- Chou, H.S., Hsieh, C.C., Yang, H.R., Wang, L., Arakawa, Y., Brown, K., Wu, Q., Lin, F., Peters, M., Fung, J.J., et al. (2011). Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice. Hepatology 53, 1007-1019. https://doi.org/10.1002/hep.24162
- Ding, Y., Xu, J., and Bromberg, J.S. (2012). Regulatory T cell migration during an immune response. Trends Immunol. 33, 174-180. https://doi.org/10.1016/j.it.2012.01.002
- Dunham, R.M., Thapa, M., Velazquez, V.M., Elrod, E.J., Denning, T.L., Pulendran, B., and Grakoui, A. (2013). Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid. J. Immunol. 190, 2009-2016. https://doi.org/10.4049/jimmunol.1201937
- Erhardt, A., Biburger, M., Papadopoulos, T., and Tiegs, G. (2007). IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice. Hepatology 45, 475-485. https://doi.org/10.1002/hep.21498
- Fu, H., Kishore, M., Gittens, B., Wang, G., Coe, D., Komarowska, I., Infante, E., Ridley, A.J., Cooper, D., Perretti, M., et al. (2014). Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation. Nat. Commun. 5, 3436. https://doi.org/10.1038/ncomms4436
- Fujimoto, M., Nakano, M., Terabe, F., Kawahata, H., Ohkawara, T., Han, Y., Ripley, B., Serada, S., Nishikawa, T., Kimura, A., et al. (2011). The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells. J. Immunol. 186, 32-40. https://doi.org/10.4049/jimmunol.0903314
- Geubel, A.P., De Galocsy, C., Alves, N., Rahier, J., and Dive, C. (1991). Liver damage caused by therapeutic vitamin A administration: estimate of dose-related toxicity in 41 cases. Gastroenterology 100, 1701-1709. https://doi.org/10.1016/0016-5085(91)90672-8
- Hall, J.A., Grainger, J.R., Spencer, S.P., and Belkaid, Y. (2011). The role of retinoic acid in tolerance and immunity. Immunity 35, 13-22. https://doi.org/10.1016/j.immuni.2011.07.002
- Haribhai, D., Lin, W., Relland, L.M., Truong, N., Williams, C.B., and Chatila, T.A. (2007). Regulatory T cells dynamically control the primary immune response to foreign antigen. J. Immunol. 178, 2961-2972. https://doi.org/10.4049/jimmunol.178.5.2961
- Hong, F., Jaruga, B., Kim, W.H., Radaeva, S., El-Assal, O.N., Tian, Z., Nguyen, V.A., and Gao, B. (2002). Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. J. Clin. Invest. 110, 1503-1513. https://doi.org/10.1172/JCI0215841
- Ichikawa, S., Mucida, D., Tyznik, A.J., Kronenberg, M., and Cheroutre, H. (2011). Hepatic stellate cells function as regulatory bystanders. J. Immunol. 186, 5549-5555. https://doi.org/10.4049/jimmunol.1003917
- Ichiki, Y., He, X.S., Shimoda, S., Ishibashi, H., Keeffe, E.B., Rossaro, L., and Gershwin, M.E. (2005). T cell immunity in hepatitis B and hepatitis C virus infection: implications for autoimmunity. Autoimmun. Rev. 4, 82-95. https://doi.org/10.1016/j.autrev.2004.12.003
- Jaruga, B., Hong, F., Kim, W.H., Sun, R., Fan, S., and Gao, B. (2004). Chronic alcohol consumption accelerates liver injury in T cell-mediated hepatitis: alcohol disregulation of NF-kappaB and STAT3 signaling pathways. Am. J. Physiol. Gastrointest Liver Physiol. 287, G471-479. https://doi.org/10.1152/ajpgi.00018.2004
- Jeong, W.I., Park, O., Suh, Y.G., Byun, J.S., Park, S.Y., Choi, E., Kim, J.K., Ko, H., Wang, H., Miller, A.M., et al. (2011). Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice. Hepatology 53, 1342-1351. https://doi.org/10.1002/hep.24190
- Kita, H., Mackay, I.R., Van De Water, J., and Gershwin, M.E. (2001). The lymphoid liver: considerations on pathways to autoimmune injury. Gastroenterology 120, 1485-1501. https://doi.org/10.1053/gast.2001.22441
- Kubota, N., Ebihara, T., Matsumoto, M., Gando, S., and Seya, T. (2010). IL-6 and IFN-alpha from dsRNA-stimulated dendritic cells control expansion of regulatory T cells. Biochem. Biophys. Res. Commun. 391, 1421-1426. https://doi.org/10.1016/j.bbrc.2009.12.081
- Lafdil, F., Wang, H., Park, O., Zhang, W., Moritoki, Y., Yin, S., Fu, X.Y., Gershwin, M.E., Lian, Z.X., and Gao, B. (2009). Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production. Gastroenterology 137, 2125-2135 e2121-2122. https://doi.org/10.1053/j.gastro.2009.08.004
- Leifeld, L., Cheng, S., Ramakers, J., Dumoulin, F.L., Trautwein, C., Sauerbruch, T., and Spengler, U. (2002). Imbalanced intrahepatic expression of interleukin 12, interferon gamma, and interleukin 10 in fulminant hepatitis B. Hepatology 36, 1001-1008. https://doi.org/10.1053/jhep.2002.35532
- Leo, M.A., and Lieber, C.S. (1982). Hepatic vitamin A depletion in alcoholic liver injury. N Engl. J. MedM 307, 597-601. https://doi.org/10.1056/NEJM198209023071006
- Li, J., Qiu, S.J., She, W.M., Wang, F.P., Gao, H., Li, L., Tu, C.T., Wang, J.Y., Shen, X.Z., and Jiang, W. (2012). Significance of the balance between regulatory T (Treg) and T helper 17 (Th17) cells during hepatitis B virus related liver fibrosis. PLoS One 7, e39307. https://doi.org/10.1371/journal.pone.0039307
- Lopez-Valencia, V., Rangel, P., Rodriguez, S., and Hernandez-Munoz, R. (2007). Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. Biochem. Pharmacol. 73, 586-596. https://doi.org/10.1016/j.bcp.2006.10.021
- Marra, F., Valente, A.J., Pinzani, M., and Abboud, H.E. (1993). Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines. J. Clin. Invest. 92, 1674-1680. https://doi.org/10.1172/JCI116753
- Mucida, D., Park, Y., Kim, G., Turovskaya, O., Scott, I., Kronenberg, M., and Cheroutre, H. (2007). Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 317, 256-260. https://doi.org/10.1126/science.1145697
- Murai, M., Turovskaya, O., Kim, G., Madan, R., Karp, C.L., Cheroutre, H., and Kronenberg, M. (2009). Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat. Immunol. 10, 1178-1184. https://doi.org/10.1038/ni.1791
- Natarajan, S.K., Thomas, S., Ramachandran, A., Pulimood, A.B., and Balasubramanian, K.A. (2005). Retinoid metabolism during development of liver cirrhosis. Arch. Biochem. Biophys. 443, 93-100. https://doi.org/10.1016/j.abb.2005.09.008
- Nollevaux, M.C., Guiot, Y., Horsmans, Y., Leclercq, I., Rahier, J., Geubel, A.P., and Sempoux, C. (2006). Hypervitaminosis A-induced liver fibrosis: stellate cell activation and daily dose consumption. Liver Int. 26, 182-186. https://doi.org/10.1111/j.1478-3231.2005.01207.x
- Radaeva, S., Wang, L., Radaev, S., Jeong, W.I., Park, O., and Gao, B. (2007). Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1. Am. J. Physiol. Gastrointest Liver Physiol. 293, G809-816. https://doi.org/10.1152/ajpgi.00212.2007
- Saiman, Y., and Friedman, S.L. (2012). The role of chemokines in acute liver injury. Front. Physiol. 3, 213.
- Schuppan, D., and Kim, Y.O. (2013). Evolving therapies for liver fibrosis. J. Clin. Invest. 123, 1887-1901. https://doi.org/10.1172/JCI66028
- Tiegs, G., Hentschel, J., and Wendel, A. (1992). A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J. Clin. Invest 90, 196-203. https://doi.org/10.1172/JCI115836
- Wei, H.X., Chuang, Y.H., Li, B., Wei, H., Sun, R., Moritoki, Y., Gershwin, M.E., Lian, Z.X., and Tian, Z. (2008). CD4+ CD25+ Foxp3+ regulatory T cells protect against T cell-mediated fulminant hepatitis in a TGF-beta-dependent manner in mice. J. Immunol. 181, 7221-7229. https://doi.org/10.4049/jimmunol.181.10.7221
- Xie, C., Wei, W., Zhang, T., Dirsch, O., and Dahmen, U. (2014). Monitoring of systemic and hepatic hemodynamic parameters in mice. J. Vis. Exp. 4, e51955.
- Yang, H.R., Chou, H.S., Gu, X., Wang, L., Brown, K.E., Fung, J.J., Lu, L., and Qian, S. (2009). Mechanistic insights into immunomodulation by hepatic stellate cells in mice: a critical role of interferon-gamma signaling. Hepatology 50, 1981-1991. https://doi.org/10.1002/hep.23202
- Yi, H.S., Lee, Y.S., Byun, J.S., Seo, W., Jeong, J.M., Park, O., Duester, G., Haseba, T., Kim, S.C., Park, K.G., et al. (2014). Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice. Hepatology 60, 1044-1053. https://doi.org/10.1002/hep.27137
- Zhang, N., Schroppel, B., Lal, G., Jakubzick, C., Mao, X., Chen, D., Yin, N., Jessberger, R., Ochando, J.C., Ding, Y., et al. (2009). Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. Immunity 30, 458-469. https://doi.org/10.1016/j.immuni.2008.12.022
- Ziouzenkova, O., Orasanu, G., Sharlach, M., Akiyama, T.E., Berger, J.P., Viereck, J., Hamilton, J.A., Tang, G., Dolnikowski, G.G., Vogel, S., et al. (2007). Retinaldehyde represses adipogenesis and diet-induced obesity. Nat. Med. 13, 695-702. https://doi.org/10.1038/nm1587
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