The Korean Journal of Medicine

  • 제86권4호
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  • Pages.519-522
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  • 2014
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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패혈증 비브리오균에 의한 위장관염에 이은 급성 화농성 척추염 1예

Vertebral Osteomyelitis Resulting from Hematogenous Spread of Vibrio Vulnificus Gastroenteritis

  • 옥혜성 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 김병기 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 김기훈 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 박만제 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 이현수 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 위유미 (성균관대학교 의과대학 삼성창원병원 내과) ;
  • 강철인 (성균관대학교 의과대학 삼성서울병원 감염내과)
  • Ok, Hea Sung (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Byeong Ki (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Ki Hoon (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Park, Man Je (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Lee, Hyoun Soo (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Wi, Yu Mi (Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Kang, Cheol-In (Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 투고 : 2013.04.14
  • 심사 : 2013.08.12
  • 발행 : 2014.04.01
⟨ 이전 논문 다음 논문 ⟩

초록

본 저자들은 문헌에 보고된 바가 없는 패혈증 비브리오균에 의한 위장관염에 이은 급성 화농성 척추염을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Vibrio vulnificus is a halophilic gram-negative bacillus capable of causing severe to life-threatening infections in high-risk populations. Osteomyelitis caused by V. vulnificus is extremely rare, and a previously reported case had been associated with an adjacent soft-tissue infection. Herein we report the first case of vertebral osteomyelitis resulting from hematogenous spread of V. vulnificus gastroenteritis. The patient was successfully treated with a combination of cefotaxime and ciprofloxacin.

키워드

참고문헌

  1. Hlady WG, Klontz KC. The epidemiology of Vibrio infections in Florida, 1981-1993. J Infect Dis 1996;173:1176-1183. https://doi.org/10.1093/infdis/173.5.1176
  2. Kim DM, Hong SJ. Vibrio vulnificus sepsis. Korean J Med 2012;82:671-679. https://doi.org/10.3904/kjm.2012.82.6.671
  3. Vartian CV, Septimus EJ. Osteomyelitis caused by Vibrio vulnificus. J Infect Dis 1990;161:363. https://doi.org/10.1093/infdis/161.2.363
  4. Park KH, Jung SI, Jung YS, Shin JH, Hwang JH. Marine bacteria as a leading cause of necrotizing fasciitis in coastal areas of South Korea. Am J Trop Med Hyg 2009;80:646-650.
  5. Kim DM, Jung SI, Jang HC, et al. Vibrio vulnificus DNA load and mortality. J Clin Microbiol 2011;49:413-415. https://doi.org/10.1128/JCM.01913-09
  6. Zimmerli W. Clinical practice: vertebral osteomyelitis. N Engl J Med 2010;362:1022-1029. https://doi.org/10.1056/NEJMcp0910753
  7. Gouliouris T, Aliyu SH, Brown NM. Spondylodiscitis: update on diagnosis and management. J Antimicrob Chemother 2010;65(Suppl 3):iii11-24.
  8. Centers for Disease Control and Prevention. Vibrio vulnificus general information: how is V. vulnificus treated? [Internet]. Atlanta (GA): Centers for Disease Control and Prevention, c2010 [cited 2010 Jun 5]. Available from: http://www.cdc.gov/nczved/divisions/dfbmd/diseases/vibriov/#treatment.
  9. Tang HJ, Chang MC, Ko WC, Huang KY, Lee CL, Chuang YC. In vitro and in vivo activities of newer fluoroquinolones against Vibrio vulnificus. Antimicrob Agents Chemother 2002;46:3580-3584. https://doi.org/10.1128/AAC.46.11.3580-3584.2002
  10. Neupane GP, Kim DM, Yun NR, Shin SH, Lim SC, Choi CH. Quantitative PCR and in vivo efficacy of antibiotics in the treatment of Vibrio vulnificus infection in a mouse model. Eur J Clin Microbiol Infect Dis 2012;31:2461-2467. https://doi.org/10.1007/s10096-012-1592-z

피인용 문헌

  1. Vibrio vulnificus infection: a persistent threat to public health vol.33, pp.6, 2014, https://doi.org/10.3904/kjim.2018.159