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A Case of Complete Recovery from Late Insidious Type of Acute Phosphate Nephropathy

지연 발현형 급성 인산염 신병증에서 완전 회복된 환자 1예

  • Kwak, Choong Hwan (Daegu Hospital) ;
  • Park, Ha Yeon (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Kim, Yae Rim (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Paek, Jin Hyuk (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Hwang, Eun Ah (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Park, Sung Bae (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Han, Seungyeup (Department of Internal Medicine, Keimyung University School of Medicine)
  • 곽충환 (대구병원) ;
  • 박하연 (계명대학교 의과대학 내과학교실) ;
  • 김예림 (계명대학교 의과대학 내과학교실) ;
  • 백진혁 (계명대학교 의과대학 내과학교실) ;
  • 황은아 (계명대학교 의과대학 내과학교실) ;
  • 박성배 (계명대학교 의과대학 내과학교실) ;
  • 한승엽 (계명대학교 의과대학 내과학교실)
  • Received : 2013.07.16
  • Accepted : 2013.09.09
  • Published : 2014.04.01

Abstract

The widespread use of colonoscopy for early detection of colorectal pathology has increased the use of osmotic laxatives for colonic cleansing. Among these, oral sodium phosphate preparations can cause renal insufficiency through the development of acute phosphate nephropathy. Acute phosphate nephropathy can be distinguished as early symptomatic and late insidious patterns. Patients whose presentation is insidious are easily overlooked and can progress to chronic kidney disease. We report a case of complete recovery from the late insidious type of acute phosphate nephropathy.

대장내시경 검사 시 경구용 인산염은 폴리에틸렌 글리콘에 비하여 적은 용량으로 더 효과적인 장세척이 가능하나 전해질 이상 및 칼슘-인 결정의 침착에 의한 급성 인산염 신병증이 보고되고 있다. 급성 인산염 신병증의 경우 많은 수의 환자들이 만성 콩팥병으로 진행하고 일부는 말기 신부전으로 진행한다고 알려져 있다. 저자들은 조직 검사에서 진단된 급성 인산염 신병증에서 완전 회복된 환자를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

  1. Markowitz GS, Perazella MA. Acute phosphate nephropathy. Kidney Int 2009;76:1027-1034. https://doi.org/10.1038/ki.2009.308
  2. Gonlusen G, Akgun H, Ertan A, Olivero J, Truong LD. Renal failure and nephrocalcinosis associated with oral sodium phosphate bowel cleansing: clinical patterns and renal biopsy findings. Arch Pathol Lab Med 2006;130:101-106.
  3. Joo WC, Lee SW, Yang DH, Han JY, Kim MJ. A case of biopsy-proven chronic kidney disease on progression from acute phosphate nephropathy. Kidney Res Clin Pract 2012;31:124-127. https://doi.org/10.1016/j.krcp.2012.04.320
  4. Chang KJ, Chang HJ, Kim BG, et al. A case of chronic renal failure after exposure to oral sodium phosphate bowel purgatives. Korean J Med 2012;83:659-663. https://doi.org/10.3904/kjm.2012.83.5.659
  5. Kim HJ, LEE BH, Kwon SH, et al. A case of acute phosphate nephropathy after sodium phosphate preparation. Korean J Nephrol 2008;27:374-377.
  6. Desmeules S, Bergeron MJ, Isenring P. Acute phosphate nephropathy and renal failure. N Engl J Med 2003;349:1006-1007. https://doi.org/10.1056/NEJM200309043491020
  7. Markowitz GS, Nasr SH, Klein P, et al. Renal failure due to acute nephrocalcinosis following oral sodium phosphate bowel cleansing. Hum Pathol 2004;35:675-684. https://doi.org/10.1016/j.humpath.2003.12.005
  8. Sayer JA, Carr G, Simmons NL. Nephrocalcinosis: molecular insights into calcium precipitation within the kidney. Clin Sci (Lond) 2004;106:549-561. https://doi.org/10.1042/CS20040048
  9. Dipalma JA, Buckley SE, Warner BA, Culpepper RM. Biochemical effects of oral sodium phosphate. Dig Dis Sci 1996;41:749-753. https://doi.org/10.1007/BF02213131
  10. Casais MN, Rosa-Diez G, Perez S, Mansilla EN, Bravo S, Bonofiglio FC. Hyperphosphatemia after sodium phosphate laxatives in low risk patients: prospective study. World J Gastroenterol 2009;15:5960-5965. https://doi.org/10.3748/wjg.15.5960