Journal of the Institute of Electronics and Information Engineers (전자공학회논문지)

The Institute of Electronics and Information Engineers (대한전자공학회)
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Measurement of Neuromagentic Evoked Fields Using Korean Magnetoencephalography system and Its Clinical Application

한국형 뇌자도 시스템을 이용한 유발 자계 측정 및 임상 응용

  • Kim, Bong Soo (EIT/LOFUS R&D Center, International St Mary's Hospital, Catholic Kwandong University) ;
  • Chang, Won Seok (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Hwang, Su-Jeong (Graduate School of Medical Science, Yonsei University) ;
  • Kim, Kiwoong (Center for Biosignals, Division of Convergence Technology, Korea Research Institute of Standards and Science) ;
  • Kwon, Hyukchan (Center for Biosignals, Division of Convergence Technology, Korea Research Institute of Standards and Science) ;
  • Yu, Kwon-Kyu (Center for Biosignals, Division of Convergence Technology, Korea Research Institute of Standards and Science) ;
  • Kim, Jin-Mok (Center for Biosignals, Division of Convergence Technology, Korea Research Institute of Standards and Science) ;
  • Lee, Yong-Ho (Center for Biosignals, Division of Convergence Technology, Korea Research Institute of Standards and Science) ;
  • Chang, Jin Woo (Department of Neurosurgery, Yonsei University College of Medicine)
  • 김봉수 (가톨릭관동대학교 국제성모병원 EIT/LOFUS 연구센터) ;
  • 장원석 (연세대학교 의과대학 신경외과학교실) ;
  • 황수정 (연세대학교 대학원 의과학전공) ;
  • 김기웅 (한국표준과학연구원 미래융합기술본부 생체신호센터) ;
  • 권혁찬 (한국표준과학연구원 미래융합기술본부 생체신호센터) ;
  • 유권규 (한국표준과학연구원 미래융합기술본부 생체신호센터) ;
  • 김진목 (한국표준과학연구원 미래융합기술본부 생체신호센터) ;
  • 이용호 (한국표준과학연구원 미래융합기술본부 생체신호센터) ;
  • 장진우 (연세대학교 의과대학 신경외과학교실)
  • Received : 2014.08.25
  • Accepted : 2014.10.06
  • Published : 2014.10.25
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Abstract

Korean magnetoencephalography (MEG) system had been developed and installed to hospital. The Korean MEG system contains helmet-shaped arrays of 152 first-order double relaxation oscillation SQUID (DROS) sensor. As a clinical application we have measured and analyzed evoked responses in patients with functional brain disease by outer stimulation as follows; 1) auditory evoked field in patients with hemifacial spasm, 2) somatosensory evoked fields in patients with tumor. We confirm that neuromagnetic data by Korean MEG system can provide useful information for pre-surgical planning or functional brain research.

시공간 분해능이 우수하고 비침습적으로 대뇌 신경활동의 측정이 가능한 뇌자도는 뇌기능 연구 및 뇌질환 진단에 유용한 진단용 의료기기이다. 순수 국내기술로 개발한 한국형 뇌자도 시스템을 임상시설(병원)에 설치하고 뇌질환 환자를 대상으로 유발자계를 측정, 분석하여 한국형 뇌자도 시스템의 임상 응용 가능성을 검토하였다. 1) 반측성 안면 경련 환자를 대상으로 소리자극에 대한 청각유발자계를 측정, 분석하여 안면신경과 청신경의 상호작용 여부 및 이명과의 연관성 검토, 2)뇌종양 환자의 정중신경 자극에 대한 체성감각 유발자계를 측정하여 뇌전증 유무에 따른 연관성 검토. 뇌자도 데이터의 분석 결과로부터 한국형 뇌자도 시스템이 뇌기능 연구 및 뇌질환 진단에 유용한 시공간적인 분석 정보를 제공할 수 있음을 시사하고 있다.

Keywords

References

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