DOI QR코드

DOI QR Code

생간건비탕가미방(生肝健脾湯加味方)을 이용한 갑상선기능저하증 치험1예(例)

A clinical study on a patient with hypothyroidism

  • 구진숙 (안동대학교 자연과학대학 생약자원학과) ;
  • 김봉현 (부부한의원) ;
  • 서부일 (대구한의대학교 한의과대학)
  • 투고 : 2014.08.08
  • 심사 : 2014.09.15
  • 발행 : 2014.09.30

초록

Objectives : Hypothyroidism is a common endocrine disorder in which the thyroid gland does not produce enough thyroid hormone. It can cause a number of symptoms, such as tiredness, poor ability to tolerate cold, and weight gain. The purpose of this study was to report the clinical effects of herbal medicine on hypothyroidism. Methods : We employed oriental medical treatments; herbal-medication (Saenggangeonbi - tang gamibang), acupuncture and moxibustion. At the same time, the patient started to exercise. We treated the patient two or three times a week with oriental therapy method. She took medicine three times a day after a meal. During taking medicine, we let the patient avoid fatty food, flour based food, and alcohol. The symptoms and normalization of the thyroxine and TSH levels are important points of evaluating the patient's condition. So the patient measured the body weight and took a blood test a time per two months and compared the results with previous results. Results : After taking treatment - acupuncture and moxibustion during 6 months - and taking herbal-medicine, the level of TSH, fT4, T4 and T3 became normalized. The body weight was decreased about 18 pounds. In advance, the symptom of tiredness, edema was much improved. Conclusion : Herbal medicine (Saenggangeonbi-tang gamibang) was effective in the treatment of hypothyroidism and it helped to normalize the level of TSH, fT4, T4 AND T3.

키워드

참고문헌

  1. Song YG. Diagnosis and treatment for hypothyroidism. J Korean Acad Farm Med. 2001 ; 22(3) : 269-74.
  2. Lee JS. Hypothyroidism. Diagnosis and Treatment. 1999 ; 19(9) : 2426-35.
  3. Choi DS. Diagnosis and treatment for hypothyroidism. dCUBE Digital Document Delivery. Drug information. 1996 ; 5 : 19-23.
  4. Doo HK. The sixth internal medicne of oriental medicine. Seoul : Oriental Medicine Research Institute. 1993 : 729, 867-74, 1042, 1059-65.
  5. Choi IG, Chae EY, Chang SK, Cho CS, Kim CJ. Effects of Jinmutang(JMT) on Hypothyroidism in Rats. J Korean Orient Int Med. 2006 ; 27(4) : 879-87.
  6. Cho CS, Kim DB, Kim CJ. The Effects of Dangfwisaeyeoktang(당귀사역탕) on the Hypothyroidism of Rats. Kor J Herbology. 2007 ; 22(1) : 95-102.
  7. Kim DH, Choi JS, Kim CJ, Cho CS. The Effects of Daeyoungjeon(DYJ) on the Hypothyroidism in Rats. The Kor J Herbology. 2007 ; 22(4) : 35-43.
  8. Kim SJ, Kim DC. Effects of Jaeumkanghwa-tang on the Rat Hypothyroidism induced by Propylthiouracil (PTU). J Orient Obstet Gynecol. 2014 ; 27(1) : 41-64. https://doi.org/10.15204/jkobgy2014.27.1.041
  9. Hong MJ, Lee BC, Ahn YM, Ahn SY. The Effects of Epimedii Herba on a Hypothyroidism Rat Model induced by PTU(6-Prophyl, 2-thiouracil). J Pharmacopuncture. 2011 ; 14(4) : 13-22. https://doi.org/10.3831/KPI.2011.14.4.013
  10. Lee SJ, Baek SH, Ahn SY, Lee BC, Ahn YM. Effects of Cistanche Deserticola on Thyroid Function in Hypothyroidism Rat Model induced by PTU (6-Prophyl, 2-thiouracil). Korean J Orient Physiol Pathol. 2011 ; 25(6) : 989-95.
  11. Kim SM, Ku SK, Cho SY, Park SJ. Effects of Bupleuri Radix on the Rat Hypothyroidism induced by PTU(6-Prophyl, 2-thiouracil). Kor J Orient Physiol Pathol. 2012 ; 26(5) : 714-23.
  12. Kim YS, Kang SK. A study of the effect of Ginseng Radix aqua-acupuncture on the hypothyroidism induced by thiourea in rats. J Kyung Hee Univ Med Cent. 1990 ; 6(2) : 202-10.
  13. Yang HT, Yoon JW, Kim KS, Song CH, Ahn CB. Study of effect of cervus nippon temminck aqua-acupuncture on the hypothyroidism induced by thiourea in rats, J Korean Acupuncture Moxibustion Med Soc. 1992 ; 9(1) : 215-27.
  14. Kim BW. The effect of Saengkankeonbi-tang and clinical analysis on 3,136 patients suffering from chronic hepatitis. J Korean Oriental Med. 1999 ; 20(2) : 427-34.
  15. Hong ND, Kim JW, Kim BW, Shon JG. Studies on the efficacy of the combined preparation of crude drugs(VI)-Effect of "Saengkankunbi-tang" on activities of the liver enzyme, protein contents and the excretory action of bile juice in the serum CCl4-intoxicated rabbits. Kor J Pharmacogn. 1982 ; 13(1) : 33-8.
  16. Kwak KK, Kim YJ, Cho CK. The effect of Saengkankeonbi-tang on 35 patients suffering from chronic hepatitis. J Korean Med Inst Daejeon Univ. 1997 ; 6(1) : 313-6.
  17. Devdhar M, Ousman YH, Burman KD. Hypothyroidism. Endocrinol Metab Clin North Am. 2007 ; 36 : 595-615. https://doi.org/10.1016/j.ecl.2007.04.008
  18. Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, Franklyn JA, Hershman JM, Burman KD, Denke MA, Gorman C, Cooper RS, Weissman NJ. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA. 2004 ; 291(2) : 228-38. https://doi.org/10.1001/jama.291.2.228
  19. Cho BY. The clinical thyroidology. the 3rd editoin. Seoul : Korea Medicine. 2010 : 437-76.
  20. Wiersinga WM. Thyroid hormone replacement therapy. Horm Res. 2001 ; 56 : 74-81. https://doi.org/10.1159/000048140
  21. Lanxiuping. Ziniziyinjianghuotang zhiliao gengnianqibumeiliaoxiao guancha. Shanxizhigong yixueyuanxuebao. 2003 ; 13(3) : 25.
  22. Sanocka D, Miesel R, Jedrzejczak P, Kurpisz MK. Oxidative stress and male infertility. J Androl. 1996 ; 17(4) : 449-54.
  23. Sahoo DK, Roy A, Chainy GB. Protective effects of vitamin E and curcumin on L-thyroxine-induced rat testicular oxidative stress. Chem Biol Interact. 2008 ; 176 : 121-8. https://doi.org/10.1016/j.cbi.2008.07.009
  24. The textbook compilation committee of Korean herbology. Korean herbology. Seoul : Younglimsa. 2012 : 155, 335, 339, 341, 351, 353, 396, 399, 411, 415, 417, 487, 657, 686.