Clinical Factors Associated with Recurrence of Nasopharyngeal Carcinoma

비인두암의 재발에 연관된 임상적 지표

  • Ok, Sohea (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Lee, Soo-Hyung (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Hwang, Sunjin (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Park, Min-Woo (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Cho, Jae-Gu (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Baek, Seung-Kuk (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Kwon, Soon-Young (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Jung, Kwang-Yoon (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine) ;
  • Woo, Jeong-Soo (Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine)
  • 옥소혜 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 이수형 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 황선진 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 박민우 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 조재구 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 백승국 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 권순영 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정광윤 (고려대학교 의과대학 이비인후-두경부외과학교실) ;
  • 우정수 (고려대학교 의과대학 이비인후-두경부외과학교실)
  • Received : 2014.01.11
  • Accepted : 2014.02.07
  • Published : 2014.05.31

Abstract

Background and Objectives : The objective of this study was to investigate clinical factors associated with recurrence of nasopharyngeal carcinoma(NPC). Materials and Methods : We performed a retrospective review of 112 diagnosed as nasopharyngeal carcinoma, treated concurrent chemo-radiotherapy(CCRT) and had complete response from March 1, 1995, to March 31, 2012. Results : Of the recurrent NPC patients, patients received 2nd line chemotherapy had more recurrence within 2 years(p=0.010). Especially, patients received 2nd line chemotherapy longer than 4 months tend to have recurrence early(p=0.035). Other factors are not different between recurrent and non-recurrent NPC patients. Conclusion : The presence and the duration of 2nd line chemotherapy are associated with early recurrence.

Keywords

References

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