Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Bladder Cancer Biomarkers: Review and Update

  • Ghafouri-Fard, Soudeh (Department of Medical Genetics, Shahid Beheshti University of Medical Sciences) ;
  • Nekoohesh, Leili (Department of Medical Biotechnology, School of Advanced Medical Technologies, Tehran University of Medical Sciences) ;
  • Motevaseli, Elahe (Department of Medical Biotechnology, School of Advanced Medical Technologies, Tehran University of Medical Sciences)
  • Published : 2014.03.30
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Abstract

As the recurrence and mortality rates of bladder cancer are high, research is needed to find suitable biomarkers for early detection, evaluation of prognosis, and surveillance of drug responses. We performed a computerized search of the Medline/PubMed databases with the key words bladder cancer, biomarker, early detection, prognosis and drug response. Several markers were identified at DNA, RNA and protein levels with different sensitivities and specificities. Only a few of the potential bladder cancer biomarkers have been approved for clinical use. Efforts now should be concentrated on finding a panel of markers with acceptable sensitivity and specificity for early detection of bladder cancer.

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