Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Treatment of Lymphocytic Gastritis with Cyclosporine in a Cat

고양이 림프구성 위염에서 싸이클로스포린을 이용한 치료 증례

  • Lee, Hwajoon (College of Veterinary Medicine, Chungbuk National University) ;
  • Park, So-Young (College of Veterinary Medicine, Chungbuk National University) ;
  • Ahn, Byeongwoo (College of Veterinary Medicine, Chungbuk National University) ;
  • Yang, Mhan-Pyo (College of Veterinary Medicine, Chungbuk National University) ;
  • Kang, Ji-Houn (College of Veterinary Medicine, Chungbuk National University)
  • Accepted : 2014.02.15
  • Published : 2014.04.30
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Abstract

A 7-year-old spayed female domestic shorthair cat was referred for chronic intermittent vomiting. The frequency of vomiting increased recently, and the cat showed anorexia at presentation. There were no remarkable abnormalities on the blood analyses and diagnostic imaging. However, the endoscopic examination revealed focal erosions of the gastric body mucosa, and subsequent multiple biopsies were obtained. Histopathologic examination indicated mild to moderate lymphocytic gastritis. The vomiting was completely disappeared 7 days after the administration with prednisolone (PDS). However, because of side effects caused by the long-term PDS administration, cyclosporine was added on the prescription with tapered dose of PDS. The dog's condition improved with continued cyclosporine treatment, and no further vomiting and anorexia episodes have been noted. This case describes the successful management with administration of cyclosporine in feline lymphocytic gastritis.

7세 중성화된 암컷 고양이가 3개월 동안 지속된 간헐적인 구토 증상으로 진료 의뢰되었다. 혈액 검사와 진단영상학적 검사에서 비정상적인 소견은 관찰되지 않았다. 내시경 검사에서 위 동체 점막에 국소적인 미란이 관찰되었고, 해당 병변들에 대한 조직병리학적 검사를 통해 림프구성 위염으로 진단하였다. 프레드니솔론 투약 7일 후에 구토 및 식욕 부진 증상은 소실되었지만, 장기간 투약에 의한 부작용 발생 때문에 프레드니솔론 대신에 싸이클로스포린을 처방하였다. 환자의 상태는 개선되었고, 구토와 식욕부진은 더 이상 관찰되지 않았다. 본보는 만성 구토를 보이는 고양이 림프구성 위염에 있어 싸이클로스포린은 치료 약물로 적용 가능함을 시사한다.

Keywords

References

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