Biomaterials and Biomechanics in Bioengineering

  • 제1권2호
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  • Pages.73-79
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  • 2014
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  • 2465-9835(pISSN)
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  • 2465-9959(eISSN)
테크노프레스 (Techno-Press)
권호 표지
DOI QR코드

DOI QR Code

Polyvinyl butyral DMN-conjugates for the controlled release of singlet oxygen in medical and antimicrobial applications

  • Posavec, Damir (Institute of Inorganic Chemistry, Johannes Kepler University Linz (JKU)) ;
  • Muller, Rainer (Institute of Physical and Theoretical Chemistry, University of Regensburg) ;
  • Bogner, Udo (Institute of Physical and Theoretical Chemistry, University of Regensburg) ;
  • Bernhardt, Gunther (Institute of Pharmacy, University of Regensburg) ;
  • Knor, Gunther (Institute of Inorganic Chemistry, Johannes Kepler University Linz (JKU))
  • 투고 : 2013.12.17
  • 심사 : 2014.06.17
  • 발행 : 2014.06.25
⟨ 이전 논문 다음 논문 ⟩

초록

Covalent attachment of 1, 4-dimethylnaphthalene (DMN) based endoperoxide forming subunits to a polyvinyl butyral (PVB) backbone has been achieved. The functionalized polymer materials prepared and characterized here can serve as biocompatible carrier systems for studying cellular uptake, intermediate storage and delayed release of singlet oxygen, which opens up new doors for optimizing a variety of medical applications of photogenerated DMN-endoperoxides such as antiviral, antibacterial, antiplasmodial and antitumor activity.

키워드

과제정보

연구 과제번호 : Sensory Photoreceptors in Natural and Artificial Systems

연구 과제 주관 기관 : DFG

참고문헌

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