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Study on the Development of Two-Stage Centrifugal Blood Pump for Cardiopulmonary Support System

  • Received : 2014.05.02
  • Accepted : 2014.06.02
  • Published : 2014.12.31

Abstract

In the cardiopulmonary support system with an ECMO (extracorporeal membrane oxygenation), a higher pump head is demanded for a blood pump. In order to realize a blood pump with higher pump head, higher anti-hemolysis and thrombosis performances, a study on the development of unprecedented multistage blood pump was conducted. In consideration of the application of the blood pump for pediatric patients, a miniature two-stage centrifugal blood pump with the impeller's diameter of 40mm was designed and the performance was examined in experiments and computations. Some useful knowledge for a design of the blood pump with higher anti-hemolysis and thrombosis performances was obtained.

Keywords

References

  1. Horiguchi, H., Tsukiya, T., Takemika, T., Nomoto, T., and Tsujimoto, Y., 2013, "Improvement of Two-Stage Centrifugal Blood Pump for Cardiopulmonary Support System and Evaluation of Anti-Hemolysis Performance (in Japanese)," Transactions of the JSME, Series B, Vol. 79, No. 800, pp. 11-23.
  2. Lou, S., MacLaren, G., Best D., Delzoppo, C., and Butt, W., 2014, "Hemolysis in Pediatric Patients Receiving Centrifugal-Pump Extracorporeal Membrane Oxygenation: Prevalence, Risk Factors, and Outcomes," Critical Care Medicine, Vol. 42, No. 5, pp. 1213-1220. https://doi.org/10.1097/CCM.0000000000000128
  3. Takeda, H., 2005, "Basic Design on Pumps (in Japanese)," Dengyosha Technical Review, Vol. 29, No. 2, pp. 7-14. ( http://www.dmw.co.jp/technical/pdf/no57.pdf)
  4. Schima, H., Muller, M. R., Papantonis, D., Schlusche, C., Huber, L., Schmidt, C., Trubel, W., Thoma, H., Losert, U., and Wolner, E., 1993, "Minimization of Hemolysis in Centrifugal Blood Pumps: Influence of Different Geometries," The International Journal of Artificial Organs, Vol. 16, No. 7, pp. 521-529.
  5. Miyazoe, Y., Sawairi, T., Ito, K., Konishi, Y., Yamane, T., Nishida, M, Masuzawa, T., Takiura, K., and Taenaka, Y., 1998, "Computational Fluid Dynamic Analysis to Establish Design Process of Centrifugal Blood Pumps," Artificial Organs, Vol. 22, No. 5, pp. 381-385. https://doi.org/10.1046/j.1525-1594.1998.06169.x
  6. Masuzawa, T., Tsukiya, T., Endo, S., Tatsumi, E., Taenaka, Y., Yamane, T., Nishida, M., Asztalos, B., Miyazoe, Y., Ito, K., Sawairi, T., and Konishi, Y., 1998, "Effect of Gaps Between Impeller Tip and Casing Wall upon Hemolysis Property of a Centrifugal Blood Pump (in Japanese)," Journal of Life Support Engineering, Vol. 10, No. 3, pp. 102-105. (https://www.jstage.jst.go.jp/article/lifesupport1996/10/3/10_3_102/_pdf)
  7. ANSYS, Inc., 2006, "Modeling Flow Near the Wall", ANSYS CFX-Solver Modeling Guide, Release 11, pp.125-127.
  8. ANSYS, Inc., 2006, "Modeling Flow Near the Wall", ANSYS CFX-Solver Theory Guide, Release 11, pp.110-111.
  9. Kameneva, M. V., Burgreen, G. W., Kono, K., Repko, B., Antaki, J. F., and Umezu, M., 2004, "Effects of Turbulent Stresses upon Mechanical Hemolysis: Experimental and Computational Analysis," ASAIO Journal, Vol. 50, No. 5, pp. 418-423. https://doi.org/10.1097/01.MAT.0000136512.36370.B5
  10. Kurokawa, J., Choi, Y-D., Ishii, M., Matsui, J., and Imamura, H., 2003, "Theoretical Head of Semi-Open Impeller," Proceedings of the 7th Asian International Conference on Fluid Machinery, No. 40030, pp. 1-7.

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  2. Principle and basic property of the sequential flow pump vol.20, pp.3, 2017, https://doi.org/10.1007/s10047-017-0959-4