Radiation Oncology Journal

The Korean Society for Radiation Oncology (대한방사선종양학회)
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Radiation recall dermatitis induced by tamoxifen during adjuvant breast cancer treatment

  • Rhee, Jiyoung (Department of Internal Medicine, Jeju National University Hospital) ;
  • Kim, Gwi Eon (Department of Radiation Oncology, Jeju National University Hospital) ;
  • Lee, Chang Hyun (Department of General Surgery, Jeju National University Hospital) ;
  • Kwon, Jung-Mi (Department of Internal Medicine, Jeju National University Hospital) ;
  • Han, Sang-Hoon (Department of Internal Medicine, Jeju National University Hospital) ;
  • Kim, Young Suk (Department of Radiation Oncology, Jeju National University Hospital) ;
  • Kim, Woo-Kun (Department of Internal Medicine, Jeju National University Hospital)
  • Received : 2014.06.09
  • Accepted : 2014.09.29
  • Published : 2014.12.31
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Abstract

Tamoxifen and radiotherapy are used in breast cancer treatment worldwide. Radiation recall dermatitis (RRD), induced by tamoxifen, has been rarely reported. Herein, we report a RRD case induced by tamoxifen. A 47-year-old woman had a right quadrantectomy and an axillary lymph node dissection due to breast cancer. The tumor was staged pT2N0; it was hormone receptor positive, and human epidermal growth factor receptor 2 negative. The patient received adjuvant chemotherapy followed by tamoxifen and radiotherapy. After 22 months of tamoxifen, the patient developed a localized heating sensation, tenderness, edema, and redness at the irradiated area of the right breast. The symptoms improved within 1 week without treatment. Three weeks later, however, the patient developed similar symptoms in the same area of the breast. She continued tamoxifen before and during dermatitis, and symptoms resolved within 1 week.

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References

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