DOI QR코드

DOI QR Code

Exposure to Formaldehyde of Ambulatory Care Nurses in University Hospital

대학병원 내 외래간호사의 포름알데히드 노출 평가

  • Gu, Dongchul (Department of Occupational & Environmental Medicine, Pusan National University Yangsan Hospital) ;
  • Lee, Chaekwan (Institute of Environmental and Occupational Medicine & Department of Occupational and Environmental Medicine, Pusan Paik Hospital, Inje University) ;
  • Lee, Jaewan (Department of Occupational & Environmental Medicine, Pusan National University Yangsan Hospital) ;
  • Lee, Suyeon (Department of Occupational & Environmental Medicine, Pusan National University Yangsan Hospital) ;
  • Yun, Soonyoung (Department of Occupational & Environmental Medicine, Pusan National University Yangsan Hospital) ;
  • Han, Areum (Department of Occupational & Environmental Medicine, Pusan National University Yangsan Hospital) ;
  • Kim, Hyunju (Department of Occupational & Environmental Medicine, Pusan National University Yangsan Hospital) ;
  • Park, Yeongbeom (Department of Food Processing and Bakery, Gangwon Provincial College) ;
  • Jeong, Seongwook (Institute of Environmental and Occupational Medicine & Department of Occupational and Environmental Medicine, Pusan Paik Hospital, Inje University) ;
  • Moon, Chanseok (Department of Industrial Health, Pusan Catholic University)
  • 구동철 (양산부산대학교병원 직업환경의학과) ;
  • 이채관 (인제대학교 부산백병원 직업환경의학과 환경.산업의학연구소) ;
  • 이재환 (양산부산대학교병원 직업환경의학과) ;
  • 이수연 (양산부산대학교병원 직업환경의학과) ;
  • 윤순영 (양산부산대학교병원 직업환경의학과) ;
  • 한아름 (양산부산대학교병원 직업환경의학과) ;
  • 김현주 (양산부산대학교병원 직업환경의학과) ;
  • 박영범 (강원도립대학 식품가공제과제빵과) ;
  • 정성욱 (인제대학교 부산백병원 직업환경의학과 환경.산업의학연구소) ;
  • 문찬석 (부산가톨릭대학교 산업보건학과)
  • Received : 2014.10.14
  • Accepted : 2014.12.12
  • Published : 2014.12.31

Abstract

Objective: This study aimed to evaluate the exposure status of formaldehyde(FA) among the nurses in ambulatory care departments of university hospital. Methods: Two university hospitals were surveyed. The FA concentration in air were measured to target 62 nurses in 8 ambulatory care departments(89 samples). Air sampling and analysis of FA were carried out according to the OSHA Method ID-205. The survey was conducted with questionnaire asking about how to control FA and whether the nurses use the formaldehyde protectors or not. Results: FA was detected in all samples. The maximum concentration of FA was 0.258 ppm and the geometric mean was 0.023 ppm. There was no sample that exceeded any of exposure standards by OSHA-TWA whereas there were 54 samples(60.7%) that exceeded the standards by NOISH-TWA. Among 62 nurses handling FA, 13 nurses(21.0%) used the protective gloves while nobody used a gas mask. It was assessed that any of 8 common ambulatory care departments did not use a safety cabinet for FA in which local exhaust ventilation was fixed. Conclusions: Nurses in ambulatory care departments were exposed to FA. Therefore, the environment management of a workplace, the health management of a nurses, FA handling education and installing a FA cabinet with a local exhaust ventilation were needed because FA as a carcinogen was able to cause any cancer to a human body if it was emitted in air for long time.

Keywords

References

  1. American Conference of Governmental Industrial Hygienists (ACGIH). 2013 TLVs$^{(R)}$ and BEIs$^{(R)}$: Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. 2013.
  2. Alexandersson R, Hedenstiena G. Pulmonary function in wood workers exposed to formaldehyde: a prospective study. Arch Environ Health 1989;44(1):5-11 https://doi.org/10.1080/00039896.1989.9935865
  3. ASTDR(Agency for Toxic Substances and Disease Registry). Formadehyde, ToxFAQs; 1999. Available from: URL:http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=219&tid=39
  4. Bouraoui S, Mouqou S, Brahem A, Tabka F, Ben Khelifa H et al. A combination of micronucleus assay and fluorescence in situ hybridization analysis to evaluate the genotoxicity of formaldehyde. Arch Environ Contam Toxicol 2013;64(2):337-344 https://doi.org/10.1007/s00244-012-9828-6
  5. CDC-NIOSH Pocker Guide to Chemical Hazards-Formaldehyde. 2013. Available from: URL:http://www.cdc.gov/niosh/npg/npgd0293.html
  6. Costa S, Coelho P, Costa C, Silva S, Mayan O et al. Genotoxic damage in pathology anatomy laboratory workers exposed to formaldehyde. Toxicology 2008;252(1-3): 40-48 https://doi.org/10.1016/j.tox.2008.07.056
  7. Costa S, Garcia-Leston J, Coelho P, Costa C, Siva S et al. Cytogenetic and immunological effects associated with occupational formaldehyde exposure. J Toxicol Environ Health A 2013;76(4-5):217-229 https://doi.org/10.1080/15287394.2013.757212
  8. EPA(Environmental Protection Agency) office of compliance sector notebook project. Profile of the healthcare industry; 2005. p. 48
  9. Freeman LEB, Blair A, Lubin JH, Stewart PA, Hayes RB et al. Mortality From Lymphohematopoietic Malignancies Among Workers in Formaldehyde Industries: The National Cancer Institute Cohort. JNCI J Natl Cancer Inst 2009;101(10):751-761 https://doi.org/10.1093/jnci/djp096
  10. Gannon PF, Bright P, Campbell M, O'Hickey SP, Burge PS. Occupational astnam due to glutaraldehyde and formaldehyde in endoscopy and x ray departments. Thorax 1995;50(2):156-159 https://doi.org/10.1136/thx.50.2.156
  11. Gerald MJ, Jeffrey L, John IKJ. Formaldehyde esposure and asthma in children: A systematic review. Environ Health Perspect 2010;118(3):313-317
  12. Ghasemkhani M, Jahanpeyma F, Azam K. Formaldehyde exposure in some educational hospitals of tehran. Ind Health 2004;43(4):703-707
  13. Hildesheim A, Dosemeci M, Chan CC, Chen CJ, Cheng YJ et al. Occupational exposure to wood, formaldehyde, and solvents and risk of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 2001;10(11): 1145-1153
  14. IARC(International Agency for Research on Cancer) Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. 2013. Available from: URL:http://monographs.iarc.fr/ENG/Classification/index.php
  15. Ministry of Employment and Labor(MoEL). Occupational safety and health Act. 2013
  16. Occupational Safefy and Health Administration. Analytical Method Manual, ID-205: OSHA 1989.
  17. Occupational Safefy and Health Administration(OSHA): Toxic and hazadous substances. In Formaldehyde. Code of Federal Regulations: Occupational Safety and Health Administration; 2013:1910-1048. 29 CFR. Available from: URL:https://www.osha.gov/pls/oshaweb/owadisp.show_document?p_table=STANDARDS&p_id=10075
  18. Orsiers T, Sari-Minodier I, Iarmarcovai G, Bott A. Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in peripheral lymphocytes. Mutat Res 2006;605(1-2):30-41 https://doi.org/10.1016/j.mrgentox.2006.01.006
  19. Perdelli F, Spagnolo AM, Cristina ML, Sartini M, Dallera M et al. Occupational exposure to formaldehyde in three pathology departments. Ann Iq 2006;18(6):481-490
  20. Romanazzi V, Munnia A, Piro S, Allione A, Ricceri A.Malondialdehyde-deoxyguanosine adduct formation in workers of pathology wards: the role of air formaldehyde exposure. Chem Res Toxicol 2010;23(8):1342-1348 https://doi.org/10.1021/tx100083x
  21. Shaham J, Gurvich R, Kaufman Z. Sister chromatid exchange in pathology staff occupationally exposed to formaldehyde. Mutat Res 2002;514(1-2):115-123 https://doi.org/10.1016/S1383-5718(01)00334-5
  22. Viegas S, Labeira C, Nunes C, Malta-Vacas J, Gomes M et al. Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy and pathology laboratories and formaldehyde-resins production. J Occup Med Toxicol 2010;5(1):25 https://doi.org/10.1186/1745-6673-5-25
  23. Vimercati L, Carrus A, Martino T, Galise I, Minunni V et al. Formaldehyde exposure and irritative effects on medical examiners, pathologic anatomy post-graduate students and technicians. Ira J Public Health 2010; 39(4):26-36
  24. Vimercati L, Carrus A, Dell'Erba A, Assennato G. Occupational exposure to frormaldehyde in autopsy room and in pathologic anatomy laboratories. G Ital Med Lav Ergon 2007;29(3):266-268
  25. William B, Donald E, David A, Edward A, Kasmer A et al. Occupational Hazards to Hospital Personnel. Ann Intern Med 1985;102(5):658-680 https://doi.org/10.7326/0003-4819-102-5-658

Cited by

  1. Does formaldehyde have a causal association with nasopharyngeal cancer and leukaemia? vol.30, pp.1, 2018, https://doi.org/10.1186/s40557-018-0218-z