Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Quantitative Analysis of Aucklandia Lappa Using Costunolide and Dehydrocostuslactone

Costunolide와 Dehydrocostuslactone을 이용한 목향의 함량분석

  • Eom, Min Rye (Department of Medical Biomaterials Engineering, College of Biomedical Science, Kangwon National University) ;
  • Weon, Jin Bae (Department of Medical Biomaterials Engineering, College of Biomedical Science, Kangwon National University) ;
  • Yun, Bo-Ra (Department of Medical Biomaterials Engineering, College of Biomedical Science, Kangwon National University) ;
  • Lee, Jiwoo (Department of Medical Biomaterials Engineering, College of Biomedical Science, Kangwon National University) ;
  • Ma, Choong Je (Department of Medical Biomaterials Engineering, College of Biomedical Science, Kangwon National University)
  • 엄민례 (강원대학교 생물의소재공학과) ;
  • 원진배 (강원대학교 생물의소재공학과) ;
  • 윤보라 (강원대학교 생물의소재공학과) ;
  • 이지우 (강원대학교 생물의소재공학과) ;
  • 마충제 (강원대학교 생물의소재공학과)
  • Received : 2013.08.01
  • Accepted : 2013.08.19
  • Published : 2013.09.30
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Abstract

Aucklandia lappa Decne (Compositae) has been used for treatment of abdominal pain, vomiting, diarrhea, chronic inflammation, and antibacterial effect. The quality of these herbs has been affected by many factors such as collection time, place, temperature, cultivation environment and manufacturing process. We used costunolide and dehydrocostuslactone as marker compounds for quality evaluation of rhizome of Aucklandia lappa. 66 samples of Aucklandia lappa were collected from those habitats in Korea and China. The developed HPLC-DAD method was applied to investigate for quality control of Aucklandia lappa samples. The average contents of the costunolide and dehydrocostuslactone were 2.3895% and 0.9258%, respectively. The principal component analysis (PCA) exhibited that classification of Aucklandia lappa according to origin not separated. Results of this study may be satisfactory applied to determination of content criteria of Aucklandia lappa.

Keywords

References

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