Natural Product Sciences

  • 제19권3호
  • /
  • Pages.227-230
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  • 2013
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  • 1226-3907(pISSN)
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  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

Iridoid Compounds from the Whole Plant of Galium verum var. asiaticum

  • 투고 : 2013.05.07
  • 심사 : 2013.06.14
  • 발행 : 2013.09.30
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초록

One new iridoid glycoside, 10-p-dihydrocoumaroyl-6-${\alpha}$-hydroxygeniposide (1), and six known iridoid glycoside derivatives, 10-p-dihydrocoumaroyl deacetylasperuloside (2), asperulosidic acid methylester (3), asperuloside (4), asperulosidic acid (5), deacetylasperuloside (6), and scandoside (7) were isolated from the methanolic extract of the whole plant of Galium verum var. asiaticum Nakai (Rubiaceae) through repeated column chromatography. Their chemical structures were characterized by spectroscopic analysis. This is the first report of the characterization of compounds 1 - 7 from this plant.

키워드

참고문헌

  1. Bojthe-Horvath, K., Hetenyi, F., Kocsis, A., Szabo, L., Varga-Balazs, M., MatheJr., I., and Tetenyi, P., Iridoid glycosides from Galium verum. Phytochemistry 21, 2917-2919 (1980). https://doi.org/10.1016/0031-9422(80)85068-0
  2. Chaudhuri, R.K., Afifi-Yazar, F.U., and Sticher, O., 13CNMR spectroscopy of naturally occurring iridoid glucosides and their acylated derivatives. Tetrahedron 36, 2317-2326 (1980). https://doi.org/10.1016/0040-4020(80)80128-1
  3. El-Gamal, A.A., Takeya, K., Itokawa, H., Halim, A.F., Amer, M.M., Saad, H.E.A., and Awad S.A., Anthraquinones from Galium sinaicum. Phytochemistry 40, 245-251 (1995). https://doi.org/10.1016/0031-9422(95)00145-W
  4. El-Naggar, L.J. and Beal, J.L., Iridoids. A review. J. Nat. Prod. 43, 649- 706 (1980). https://doi.org/10.1021/np50012a001
  5. Handjieva, N., Mitova, M., Ancev, M., and Popov, S., Iridoid glucosides from Galium album and G. lovcense. Phytochemistry 43, 625-628 (1996). https://doi.org/10.1016/0031-9422(96)00328-7
  6. Kang, B.H., Hanguksaengyakjawonsaengtaedogam Vol. II. Geobook, Seoul, pp. 393, 2008.
  7. Kim, D.K., Superoxide quenching actitity of phenolic compounds from the whole plant of Galium verum var. asiaticum. Nat. Prod. Sci., 17, 261-266 (2011).
  8. Lee, J.H., Ku, C.H., Baek, N.I., Kim, S.H., Park, H.W. and Kim, D.K., Phytochemical constituents from Diodia teres. Arch. Pharm. Res. 27, 40-43 (2004). https://doi.org/10.1007/BF02980043
  9. Lee, T.B., In Coloured flora of Korea. Hyangmunsa, Seoul, pp. 696, 2003.
  10. Lee, W.T., In Coloured standard illustration of Korean plants. Academy Publishing Co., Seoul, pp. 691, 1996.
  11. Morimoto, M., Tanimoto, K., Sakatani, A., and Komai, K., Antifeedant activity of an anthraquinone aldehyde in Galium aparine L. against Spodoptera litura F. Phytochemistry 60, 163-166 (2002). https://doi.org/10.1016/S0031-9422(02)00095-X
  12. Myagoshi, M., Amagaya, S., and Ogihara, Y., The structure transformation of gardenoside and its related iridoids compounds by acid and $\beta$-glucosidase. Planta Med. 53, 462-464 (1987). https://doi.org/10.1055/s-2006-962773
  13. Peng, J.N., Feng, X.Z., Li, G.Y., and Liang, X.T., Chemical investigation of genus hedyotis II. Isolation and identification of iridoids from Hedyotis chrysotrichaq. Acta Pharmaceutica Sinica 32, 908-913 (1997).
  14. de Rosa, S., Iodice, C., Mitova, M., Handjieva, N., Popov, S., and Anchev, M., Triterpene saponins and iridoid glucosides from Galium rivale. Phytochemistry 54, 751-756 (2000). https://doi.org/10.1016/S0031-9422(00)00149-7
  15. Takeda, Y., Shimidzu, H., Mizuno, K., Inouchi S., Masuda, T., Hirata, E., Shinzato, T., Aramoto, M., and Otsuka, H., An iridoid glucoside dimer and non-glycosidic iridoid from the leaves of Lasianthus wallichii. Chem. Pharm. Bull. 50, 1395-1397 (2002). https://doi.org/10.1248/cpb.50.1395
  16. Uesato, S., Ueda, M., Inouye, H., Kuwajima, H., Yatsuzuka, M., and Takaishi, K., Iridoids from Galium mollugo. Phytochemistry 23, 2535- 2537 (1984). https://doi.org/10.1016/S0031-9422(00)84093-5