Journal of Korean Foot and Ankle Society (대한족부족관절학회지)

Korean Foot & Ankle Society (대한족부족관절학회)
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Pyridoxine in the Treatment of Peripheral Nerve Related Foot Pain

족부의 말초 신경 병변으로 인한 통증에서 피리독신의 사용

  • Bae, Su-Young (Department of Orthopedic Surgery, Sanggye Paik Hospital, Inje University) ;
  • Jung, Eui Yub (Department of Orthopedic Surgery, Sanggye Paik Hospital, Inje University) ;
  • Oh, Su Chan (The 3rd Artillery Brigade, 5882 Unit)
  • 배서영 (인제대학교 상계백병원 정형외과학교실) ;
  • 정의엽 (인제대학교 상계백병원 정형외과학교실) ;
  • 오수찬 (대한민국 육군 5882 부대 3포병여단)
  • Received : 2013.07.14
  • Accepted : 2013.08.20
  • Published : 2013.09.15
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Abstract

Purpose: We analyzed retrospectively the effect of pyridoxine in the treatment of peripheral nerve related foot pain because we have seen favorable clinical results from it as a monotherapy. Materials and Methods: We analyzed the clinical results of 200 cases of peripheral nerve related foot pain, treated with pyridoxine from March 2009 to February 2012. We devided them into three groups, peripheral neuritis, Morton's neuroma and posttraumatic neuralgia and recorded percentage of improvement of pain, compared to initial pain level at 2 weeks and 6 weeks. Results: There were 127 peripheral neuritis cases, 22 Morton's neuroma and 51 posttraumatic neuralgia. At 2 weeks after treatment, 135 cases(67.5%) showed pain relief. At 6 weeks, 36 cases(21%) showed complete improvement of pain, 81 cases(47%) showed more than 50 % of improvement, 22 cases(13%) showed less than 50% of improvement and 33 cases(19%) showed no improvement. There are 4 cases of gastrointestinal discomfort and 2 cases of aggravation of nervy pain. Conclusion: Pyridoxine was effective drug in the treatment of peripheral neuropathic pain in terms of pain relief, safety and cost effectiveness. So it can be an available first line drug before adding other drugs.

Keywords

References

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