Study of Relationship between Metabolic Syndrome and Bone Mineral Density on Post Menopausal Chronic Low Back Pain Patients Under Oriental Medicine Treatment

요통으로 한방치료중인 폐경 후 여성의 대사증후군 요인이 골밀도에 미치는 영향에 관한 연구

  • Lee, Jong Deok (Department of Radiology, College of Korean Medicine, Wonkwang University) ;
  • Kim, Dong Woung (Department of Radiology, College of Korean Medicine, Wonkwang University)
  • 이종덕 (원광대학교 광주한방병원 영상의학과) ;
  • 김동웅 (원광대학교 광주한방병원 영상의학과)
  • Received : 2013.01.14
  • Accepted : 2013.02.21
  • Published : 2013.02.25

Abstract

This study was performed from April, 2007 to August, 2012 with female patients who were being treated for and suffering from chronic lumbar pain for periods of 6 months and over. The 53 female patients were diagnosed with osteoporosis by having a T-Score of <-2.5 in a bone mineral density(BMD), as well as showing signs of metabolic syndrome. This was deduced by taking measurements of blood pressure, carrying out blood-chemical examinations and physical measurements such as weight, height, waist measurement and body mass index(BMI). After 5 minutes rest, the patient's blood pressure, height and weight were measured. BMI was calculated using the equation BMI = weight (Kg)/height ($m^2$). The patients had their blood taken in a fasted state(more than 12hours), the fasting blood sugar, total cholesterol, triglyceride, HDL-cholesterol were measured. The average BMD and T-score were calculated by measuring BMD(mg/cc) of L1-L3 using QCT. In a correlation analysis of the physical examinations, clinical character of metabolic syndrome and T-score, the result showed that age and T-score had a negative correlation(r=-0.699, p<0.01) as did triglyceride and T-score (r=-0.047, p<0.01), where as weight(r=0.239, p<0.05) and height(r-=0.329, p<0.01) and T-score had a positive correlation. There was no significant correlation with total cholesterol, HDL cholesterol, blood sugar, blood pressure and T-score. This study showed that there are significant correlations with age, weight, height and T-score. But there are no significant correlations with total cholesterol, HDL cholesterol, blood sugar, blood pressure and T-score and that these did not influence bone density. Further research with more subjects is required to determine whether there is a correlation of clinical character of metabolic syndrome and T-score.

Keywords

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