DOI QR코드

DOI QR Code

Successful Treatment of Two Patients with Immune Thrombocytopenic Purpura Using Herbal Decoction

  • Kwon, Soo Young (Department of International Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Jang, Eun Gyeong (Department of International Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Cho, Young Hwan (Department of International Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Jang Hoon (Department of International Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Young Chul (Department of International Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Hong, Jung Woo (Department of International Medicine, College of Korean Medicine, Kyung Hee University)
  • Received : 2013.05.03
  • Accepted : 2013.05.30
  • Published : 2013.06.30

Abstract

Objectives: This case report was conducted to introduce the effectiveness of herbal decoction on patients with chronic immune thrombocytopenic purpura (ITP). Methods: We closely observed two patients who were admitted to the Department of Internal Medicine 1 of Kyung-Hee Korean Medical Hospital due to ITP. We gave a herbal decoction to these patients and then analyzed the changes in their general conditions as well as blood test results. Results and Conclusions: The treatment with herbal decoctions was helpful for ITP patients.

Keywords

References

  1. British Committee for Standards in Haematology General Haematology Task Force. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br J Haematol. 2003; 120:574. https://doi.org/10.1046/j.1365-2141.2003.04131.x
  2. Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002; 346:99 https://doi.org/10.1056/NEJMoa011262
  3. Frederiksen H, Schmidt K. The incidence of idiopathic thrombocytopenic purpura in adults increases with age. Blood. 1999; 94:909.
  4. Zeller B, Rajantie J, Hedlund-Treutiger I, Tedgard U, Wesenberg F, Jonsson OG, et al. Childhood idiopathic thrombocytopenic purpura in the Nordic countries: epidemiology and predictors of chronic disease. Acta Paediatrica. 2005; 94:178. https://doi.org/10.1080/08035250410025294
  5. Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010; 115:168. https://doi.org/10.1182/blood-2009-06-225565
  6. Michel M, Lee K, Piette JC, Fromont P, Schaeffer A, Bierling P, et al. Platelet autoantibodies and lupus-associated thrombocytopenia. Br J Haematol. 2002; 119:354. https://doi.org/10.1046/j.1365-2141.2002.03817.x
  7. Kuwana M, Kaburaki J, Okazaki Y, Miyazaki H, Ikeda Y. Two types of autoantibody-mediated thrombocytopenia in patients with systemic lupus erythematosus. Rheumatology (Oxford). 2006; 45:851. https://doi.org/10.1093/rheumatology/kel010
  8. Zeller B, Rajantie J, Hedlund-Treutiger I, Tedgard U, Wesenberg F, Jonsson OG, et al. Childhood idiopathic thrombocytopenic purpura in the Nordic countries: epidemiology and predictors of chronic disease. Acta Paediatr. 2005; 94:178. https://doi.org/10.1080/08035250410025294
  9. Kühne T, Buchanan GR, Zimmerman S, Michaels LA, Kohan R, Berchtold W, et al. A prospective comparative study of 2540 infants and children with newly diagnosed idiopathic thrombocytopenic purpura (ITP) from the Intercontinental Childhood ITP Study Group. J Pediatr. 2003; 143:605. https://doi.org/10.1067/S0022-3476(03)00535-3
  10. Rosthoj S, Hedlund-Treutiger I, Rajantie J, Zeller B, Jonsson OG, Elinder G, et al. Duration and morbidity of newly diagnosed idiopathic thrombocytopenic purpura in children: A prospective Nordic study of an unselected cohort. J Pediatr. 2003; 143:302. https://doi.org/10.1067/S0022-3476(03)00245-2
  11. Segal JB, Powe NR. Prevalence of immune thrombocytopenia: analyses of administrative data. J Thromb Haemost. 2006; 4:2377. https://doi.org/10.1111/j.1538-7836.2006.02147.x
  12. Stasi R, Stipa E, Masi M, Cecconi M, Scimo MT, Oliva F, et al. Long-term observation of 208 adults with chronic idiopathic thrombocytopenic purpura. Am J Med. 1995; 98:436. https://doi.org/10.1016/S0002-9343(99)80342-8
  13. Portielje JE, Westendorp RG, Kluin-Nelemans HC, Brand A. Morbidity and mortality in adults with idiopathic thrombocytopenic purpura. Blood. 2001; 97:2549. https://doi.org/10.1182/blood.V97.9.2549
  14. Neylon AJ, Saunders PW, Howard MR, Proctor SJ, Taylor PR. Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population-based cohort of 245 patients. Br J Haematol. 2003; 122:966. https://doi.org/10.1046/j.1365-2141.2003.04547.x
  15. Lacey JV, Penner JA. Management of idiopathic thrombocytopenic purpura in the adult. Semin Thromb Hemost. 1977; 3:160.
  16. George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996; 88:3.
  17. Rodeghiero F, Stasi R, Gernsheimer T, Michel M, Provan D, Arnold DM, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood. 2009; 113:2386. https://doi.org/10.1182/blood-2008-07-162503
  18. Toltl LJ, Arnold DM. Pathophysiology and mana gement of chronic immune thrombocytopenia: fo cusing on what matters. Br J Haematol. 2011; 152:52. https://doi.org/10.1111/j.1365-2141.2010.08412.x
  19. Guidry JA, George JN, Vesely SK, Kennison SM, Terrell DR. Corticosteroid side-effects and risk for bleeding in immune thrombocytopenic purpura: patient and hematologist perspectives. Eur J Haematol. 2009; 83:175. https://doi.org/10.1111/j.1600-0609.2009.01265.x
  20. British Committee for Standards in Haematology General Haematology Task Force. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br J Haematol. 2003; 120:574. https://doi.org/10.1046/j.1365-2141.2003.04131.x
  21. Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010; 115:168. https://doi.org/10.1182/blood-2009-06-225565
  22. Neunert C, Lim W, Crowther M, Cohen A, Solberg L Jr, Crowther MA. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood 2011; 117:4190. https://doi.org/10.1182/blood-2010-08-302984
  23. George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996; 88:3.
  24. Hujun. Donguibogam. Seoul; Bubinmunhwasa. 2007:799.
  25. Korean Medicine College Hepatology faculty. Hepato-internal medicine. Seoul: Dongyang medical Publishing Company. 2013;616,620-21.
  26. Choi MY, Lee SB, Kim SH, Kim YC, Lee JH, Woo HJ. A case report of ITP in a child patient. The Society of Korean Oriental Internal Medicine. 2007;200-206
  27. Han CW, Kim CW, Lee JE, Rhy KR, Kim YC, Lee JH, et al. Therapeutic response of herbal medicine in 8 adult patients with idiopathic thrombocytopenic purpura. The Society of Korean Oriental Internal Medicine. 2004;82-94
  28. Park SM, Seong HS, Han CW, Kim DW, Kim YC, Lee JH, et al. A clinical report on 5 cases of ITP in adults administered herbal medicine. The Korean Society for Oriental Internal Medicine. 2002; 187-192.